Results 71 to 80 of about 4,977 (213)

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the same dose of ICS alone for adults with asthma. [PDF]

, 2015
BACKGROUND: Despite the availability of several evidence-based therapies and non-pharmacological strategies to improve control of symptoms and prevent exacerbations of asthma, patients with asthma continue to be at risk for mortality and morbidity ...
Allison, Barnes, Bateman, Beeh, Befekadu, Casale, Casale, Chauhan, Chauhan, Corren, Ducharme, Gosens, Karner, Kerstjens, Kew, Ohta, Paggiaro, Paggiaro, Peters, Rodrigo, Tian, Vandewalker, Vogelberg, World Health Organization   +23 more
core   +2 more sources

Oral hyoscine butylbromide exerts spasmolytic effects in both gastrointestinal and urogenital tissues in rats

British Journal of Pharmacology, Volume 182, Issue 11, Page 2487-2502, June 2025.
Background and Purpose Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond the GI tract to be questioned.
Sara Traserra, Terence Appelqvist, Robert Lange, Maura Corsetti, Marcel Jimenez   +4 more
wiley   +1 more source

Ten years of tiotropium: clinical impact and patient perspectives

International Journal of COPD, 2013
Abebaw M Yohannes,1 Martin J Connolly,2 Nicola A Hanania31Manchester Metropolitan University, Department of Health Professions, Manchester, UK; 2University of Auckland, Freemasons’ Department of Geriatric Medicine, Auckland, New Zealand ...
Yohannes AM, Connolly MJ, Hanania NA
doaj  

COPD: Optimizing Treatment [PDF]

, 2015
A guideline update and an expanded armamentarium have many physicians wondering how best to treat patients with COPD. Chronic obstructive pulmonary disease (COPD) carries a high disease burden. In 2012, it was the 4th leading cause of death worldwide.1,2
Ahmed-Sarwar, Nabila, Holub, David C, Pierce, Deirdre P   +2 more
core   +1 more source

Long-acting beta2-agonists for chronic obstructive pulmonary disease. [PDF]

, 2013
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a respiratory disease that causes progressive symptoms of breathlessness, cough and mucus build-up.
Aalbers, Allegra, Amgott, Anderson, Appleton, Arievich, Bateman, Bateman, Baumgartner, Beeh, Berger, Bleecker, Bleecker, Bogdan, Bogdan, Boyd, Boyd, Briggs, British Medical Association and the Royal Pharmaceutical Society of Great Britain, Brusasco, Brusasco, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Campbell, Campbell, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Chapman, Chapman, Cheyne, Chong, Chong, Corhay, Dahl, Dahl, Dahl, Dahl, Dahl, Dahl, Dal Negro, Dal Negro, Doherty, Doherty, Doherty, Doherty, Donohue, Donohue, Donohue, Donohue, Effing, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Geake, Greefhorst, Greefhorst, Greefhorst, Gross, Hanania, Hanania, Hanrahan, Hanrahan, Hanrahan, Hanrahan, Hanrahan, Higgins, Hogan, Horstman, Hunjan, Hunjan, Hutchinson, Jenkins, Jenkins, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Karner, Karner, Karner, Karner, Karner, Keene, Kerwin, Kerwin, Khamis, Kliber, Kornmann, Kornmann, Kristufek, Kristufek, Kristufek, Lacasse, Laties, Littner, Lofdahl, Lofdahl, Lofdahl, Lofdahl, Mahler, Mahler, Mahler, Mahler, Matiz-Bueno, Matiz-Bueno, McDonough, McGarvey, Meer, Nannini, Nannini, Nannini, Nelson, Nelson, Nelson, Nelson, Nitschmann, Noord, Noord, Puhan, Qaseem, Rennard, Rennard, Rennard, Rennard, Rodrigo, Rossi, Rutten-van Molken, Rutten-van Mölken, Sacchetta, Sciurba, Song, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Stahl, Steffensen, Steffensen, Stockley, Stockley, Szafranski, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Vestbo, Vestbo, Vestbo, Vestbo, Vogelmeier, Vogelmeier, Wadbo, Wang, Watkins, Welsh, Yang   +198 more
core   +1 more source

Clinical Application Guideline of Combination With Traditional Chinese Medicine and Western Medicine in the Prevention and Treatment of Chronic Obstructive Pulmonary Disease (2024)

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Aim Chronic Obstructive Pulmonary Disease (COPD) is a common chronic airway disease that can lead to decreased lung function in patients. It places a heavy economic burden on patients and society. Traditional Chinese medicine (TCM) and Western medicine have played important roles in managing COPD.
Di Wu, Wei Liu, Jianxin Wang, Wei Chen, Mengyao Shi, Lu Zhang, Hui Wang, Huanzhang Ding, Xiao Ma, Yating Gao, Zengtao Sun, Jiangtao Lin, Hongchun Zhang, Suyun Li, Zhuying Li, Zhenhui Lu, Fuqiang Wen, Zegeng Li   +17 more
wiley   +1 more source

Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD [PDF]

, 2015
Objective We performed a review of studies of fluticasone propionate (FP)/salmeterol (SAL) (combination inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA)) in patients with COPD, which measured baseline (pretreatment) blood eosinophil levels, to ...
Barnes, NC, Jones, PW, Lettis, S, Locantore, N, Pascoe, S, Pavord, ID, Wedzicha, JA   +6 more
core   +1 more source

Dose of Inhaled Corticosteroid in Chronic Obstructive Pulmonary Disease and Risks of Osteoporosis or Fracture—A Systematic Review and Meta‐Analysis

The Clinical Respiratory Journal, Volume 19, Issue 5, May 2025.
High‐dose, but not medium‐ and low‐dose, ICS use in COPD is associated with risks of osteoporosis or fractures. ABSTRACT Background Inhaled corticosteroid (ICS) is a major pharmacotherapy for chronic obstructive pulmonary disease (COPD), which is associated with various adverse effects.
Wang Chun Kwok, Chung Ki Tsui, Sze Him Isaac Leung, Shuk Man Ngai, David Chi Leung Lam, Mary Sau Man Ip, James Chung Man Ho   +6 more
wiley   +1 more source

Use of tiotropium in patients with COPD aged 80 years and older [PDF]

, 2013
The purpose of this study was to examine clinical features and treatment modality approaches in patients with chronic obstructive pulmonary disease (COPD), particularly in those aged 80 years and older.
Hizawa Nobuyuki, Kagohashi Katsunori, Kawaguchi Mio, Kurishima Koichi, Miyazaki Kunihiko, Nakazawa Kensuke, Ohara Gen, Sato Shinya, Satoh Hiroaki, Tamura Tomohiro, 佐藤 浩昭, 川口 未央, 栗島 浩一, 檜澤 伸之, 籠橋 克紀   +14 more
core   +1 more source

What is the influence of exacerbations on pulmonary function in pediatric and adolescent patients with severe asthma despite controller therapies?

Clinical and Translational Allergy, Volume 15, Issue 4, April 2025.
Abstract Background Although exacerbations are common in severe asthma, there have been few longitudinal studies evaluating their effect on lung function parameters. This study aimed to evaluate the impact of exacerbations on lung function in children and adolescents with severe asthma in Brazil.
A. Z. P. Brandão, L. M. L. B. F. Lasmar, L. M. A. S. Pertence, M. I. R. Vieira, G. B. Lasmar, V. O. Ganem, E. V. Mancuzo, M. V. N. P. de Queiroz   +7 more
wiley   +1 more source