Results 1 to 10 of about 35,159 (258)

Structural Evolution of TIR-Domain Signalosomes [PDF]

open access: yesFrontiers in Immunology, 2021
TIR (Toll/interleukin-1 receptor/resistance protein) domains are cytoplasmic domains widely found in animals and plants, where they are essential components of the innate immune system.
Surekha Nimma   +13 more
doaj   +5 more sources

Structure and Function of the TIR Domain from the Grape NLR Protein RPV1

open access: yesFrontiers in Plant Science, 2016
The N-terminal Toll/interleukin-1 receptor/resistance protein (TIR) domain has been shown to be both necessary and sufficient for defence signalling in the model plants flax and Arabidopsis.
Simon J Williams   +2 more
exaly   +3 more sources

TIR

open access: yesOpen Respiratory Archives, 2023
doaj   +2 more sources

Associations of time in tight range, time in range, and glycated hemoglobin with albuminuria and diabetic kidney disease in adult type 2 diabetes: a cross-sectional study [PDF]

open access: yesBMC Endocrine Disorders
Aims To evaluate associations of the indicators of glycemic control, HbA1c, continuous glucose monitoring (CGM)-derived time in tight range (TITR; 70–140 mg/dL), and time in range (TIR; 70–180 mg/dL) with albuminuria and diabetic kidney disease (DKD) in ...
Yanling Yang   +8 more
doaj   +2 more sources

Évaluation du temps de réaction chez les tireurs experts et non-experts

open access: yesRéflexions Sportives, 2023
Les tireurs démontrent leur talent en brisant des plateaux qui volent à 100 km/h. Une telle compétence nécessite de nombreuses années de pratique (Ericsson et al., 1993).
Karim Boukallouch
doaj   +1 more source

Continuous glucose monitoring reveals a novel association between duration and severity of hypoglycemia, and small nerve fiber injury in patients with diabetes

open access: yesEndocrine Connections, 2022
Objective: Continuous glucose monitoring (CGM) has revealed that glycemic variability and low time in range are associated with albuminuria and retinopathy.
Hoda Gad   +21 more
doaj   +1 more source

Reconstructing the TIR Side of the Myddosome: a Paradigm for TIR-TIR Interactions [PDF]

open access: yesStructure, 2016
Members of the Toll-like receptor and interleukin-1 (IL-1) receptor families all signal via Toll/IL-1R (TIR) domain-driven assemblies with adaptors such as MyD88. We here combine the mammalian two-hybrid system MAPPIT and saturation mutagenesis to complement and extend crystallographic and nuclear magnetic resonance data, and reveal how TIR domains ...
Laurens Vyncke   +7 more
openaire   +2 more sources

It starts with TIRs [PDF]

open access: yesNature Plants, 2018
The canonical auxin receptor complex mediates gene expression, but it is also necessary for responses far too rapid to be mediated by transcription. An innovative setup that uses advanced microscopy and microfluidics can record auxin-induced changes within 30 seconds during root growth.
Katarzyna, Retzer   +2 more
openaire   +2 more sources

Beneficios económicos de la certificación LEED. Edificio Centro Ático: caso de estudio

open access: yesRevista Ingeniería de Construcción, 2020
En el presente artículo se estudian los beneficios económicos de la aplicación del programa de certificación de construcciones sostenibles LEED, en el Edificio Centro Ático situado en Bogotá - Colombia.
Y. Alvarado   +3 more
doaj   +1 more source

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