Results 51 to 60 of about 6,111 (204)

Subtyping treatment response of tirofiban in acute ischemic stroke based on neuroimaging features

Clinical and Translational Science
In a previously published clinical trial, we demonstrated that tirofiban was effective and safe in acute ischemic stroke (AIS) patients who did not undergo early recanalization treatments.
Bin Han, Xu Man, Jian Ding, Yuzhu Li, Xintao Tian, Xuelian Zhu, Jiang Yu, Jinping Sun   +7 more
doaj   +1 more source

Safety of tirofiban and dual antiplatelet therapy in treating intracranial aneurysms

Stroke and Vascular Neurology, 2019
Background Endovascular treatment of intracranial aneurysms usually involves stent-assisted coiling (SAC) and flow diverters. Glycoprotein IIb/IIIa inhibitors such as tirofiban and dual antiplatelet therapy (DAPT) are required to prevent thromboembolic ...
David M Hasan, Santiago Ortega-Gutierrez, Edgar A Samaniego, Pascal Jabbour, Jorge A Roa, Daichi Nakagawa, Mario Zanaty, Emilee Gibson   +7 more
doaj   +1 more source

Safety of Tirofiban in Acute Ischemic Stroke [PDF]

Stroke, 2011
Background and Purpose— Tirofiban is a highly selective, fast-acting nonpeptide glycoprotein IIb/IIIa platelet receptor antagonist with a short half-life time. Glycoprotein IIb/IIIa antagonists are effective for the treatment of acute coronary syndromes proven in large clinical trials.
Siebler, M., Hennerici, M., Schneider, D., von Reutern , G., Seitz, R., Rother, J., Witte, O., Hamann, G., Junghans, U., Villringer, A., Fiebach, J.   +10 more
openaire   +4 more sources

Efficacy and Safety of Intracoronary versus Intravenous Administration of Tirofiban during Percutaneous Coronary Intervention for Acute Coronary Syndrome: A Meta-Analysis of Randomized Controlled Trials. [PDF]

PLoS ONE, 2015
Percutaneous coronary intervention (PCI) is known as the most effective treatment for acute coronary syndrome (ACS). However, without proper therapy and patient management, stent thrombosis after PCI may lead to another myocardial infarction. In addition
Xiuying Tang, Runjun Li, Quanmin Jing, Yingfeng Liu, Peng Liu   +4 more
doaj   +1 more source

Tirofiban induced diffuse alveolar hemorrhage

IHJ Cardiovascular Case Reports (CVCR), 2018
Alveolar hemorrhage is a dreaded complication which is seen rarely following the use of tirofiban, it is often confused with other respiratory syndromes resulting in inappropriate or delayed treatment. We present a case of acute alveolar hemorrhage following tirofiban infusion following acute coronary syndrome.
Deepak Kadeli, K S Satish, R Keshava, Nagaraj Aithal   +3 more
openaire   +3 more sources

Comparison of antithrombogenic coated and uncoated flow diverters in ruptured and unruptured cerebral aneurysms

Journal of Neuroimaging, Volume 35, Issue 1, January/February 2025.
Abstract Background and Purpose Flow diversion has become a key treatment option for complex intracranial aneurysms. Recent advancements include coated flow diverters (FDs), designed to potentially reduce the need for dual antiplatelet therapy, thereby removing the associated secondary risks while maintaining patency and low complication rates ...
Daniel Weiss, Marius Vach, Vivien L. Ivan, Sajjad Muhammad, Björn B. Hofmann, Milad Neyazi, Bernd Turowski, Marius Kaschner   +7 more
wiley   +1 more source

Blood–brain barrier profile pretreatment is associated with hemorrhagic transformation after endovascular reperfusion

Annals of Clinical and Translational Neurology, Volume 11, Issue 12, Page 3292-3299, December 2024.
Abstract Background While advances in endovascular thrombectomy (EVT) have led to high reperfusion rates, most patients treated with EVT do not avoid disability. Post‐reperfusion hemorrhagic transformation (HT) is a potential target for improving outcomes.
Richard Leigh, Pierre Seners, Vanessa Rousseau, Soren Christensen, Jean‐François Albucher, Amel Drif, Christophe Cognard, Adrien Guenego, Alain Viguier, Agnes Sommet, Nicolas Raposo, Lionel Calviere, Anne‐Christine Januel, Michael Mlynash, Fabrice Bonneville, Brice Gaudilliere, Claire Thalamas, Igor Sibon, Thomas Tourdias, Mikael Mazighi, Jeremy J Heit, Benjamin Maier, Gregory W. Albers, Jean‐Marc Olivot, on behalf of the FRAME Investigators   +24 more
wiley   +1 more source

Influence of TyG Index on Large Vascular Occlusive Stroke Following Endovascular Treatment

CNS Neuroscience &Therapeutics, Volume 30, Issue 12, December 2024.
This single‐center retrospective cohort study indicates that the triglyceride‐glucose index (TyG index), as a marker of insulin resistance, was significantly linked to worse functional outcome, increased mortality at 90 days, and a higher risk of symptomatic intracranial hemorrhage (sICH) in patients with acute ischemic stroke postendovascular ...
Wei Sun, Huixin Shen, Xiao Wu, Aini He, Xuefan Yao, Fei Chen, Haiqing Song, Xiaoqin Huang   +7 more
wiley   +1 more source

Efeito protetor de antagonista das gliproteínas IIb/IIa nas alterações hepáticas e pulmonares secundárias à isquemia e reperfusão do fígado em ratos Protective effects of an inhibitor of glycoprotein IIb/IIIa in the hepatic and pulmonary disturbances secondary to ischemia and reperfusion injury of rat’s liver

Arquivos de Gastroenterologia, 2007
RACIONAL: A lesão de isquemia e reperfusão hepática é um evento comum e responsável por considerável morbidade e mortalidade. OBJETIVO: Avaliar efeitos de inibidor da glicoproteína IIb/IIIa, cloridrato de tirofiban, nas alterações hepáticas e pulmonares ...
Leonardo F. Canedo, Marcel Autran C. Machado, Ana M. M. Coelho, Sandra N. Sampietre, Telesforo Bachella, Marcel C. C. Machado   +5 more
doaj   +1 more source

A case report of cardiac rehabilitation in coronary artery aneurysm combined with acute ST segment elevation myocardial infarction

Clinical Case Reports, Volume 12, Issue 10, October 2024.
Key Clinical Message Coronary artery aneurysm (CAA), marked by diffuse or localized dilation of artery, can cause life‐threatening complications in acute coronary syndrome. This report presents a case of CAA combined with acute ST‐segment elevation myocardial infarction, successfully treated with cardiac rehabilitation exercise therapy, offering ...
Xin‐di Feng, Zi‐lin Ma, Jia‐ying Huang, Jing‐yi Tang, Yi‐hong Wei   +4 more
wiley   +1 more source