Results 61 to 70 of about 11,453 (268)

Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini, Alla Nakonechna, Annick Barbaud, Sevim Bavbek, Gianfranco Calogiuri, Inmaculada Doña, Violeta Kvedariene, Jose Julio Laguna Martinez, Serena Liberati, Mauro Pagani, Antonino Romano   +10 more
wiley   +1 more source

Nomogram for Deep Vein Thrombosis Prediction Post‐Endovascular Thrombectomy in Acute Ischemic Stroke: A Retrospective Multicenter Observational Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Background Deep vein thrombosis (DVT) is a frequent complication following endovascular thrombectomy (EVT) in patients with acute ischaemic stroke (AIS), potentially leading to fatal pulmonary embolism (PE). Identifying patients early at high risk for DVT is clinically important.
Li Han, Teng‐Wei Pan, Li‐Li Yang, Wei‐Yang Qian, Xiao‐Ping Xu, Feng Wang, Wei‐Zhen Wang, Yang Liu, Wei‐Ying Yang   +8 more
wiley   +1 more source

Efeito protetor de antagonista das gliproteínas IIb/IIa nas alterações hepáticas e pulmonares secundárias à isquemia e reperfusão do fígado em ratos Protective effects of an inhibitor of glycoprotein IIb/IIIa in the hepatic and pulmonary disturbances secondary to ischemia and reperfusion injury of rat’s liver

Arquivos de Gastroenterologia, 2007
RACIONAL: A lesão de isquemia e reperfusão hepática é um evento comum e responsável por considerável morbidade e mortalidade. OBJETIVO: Avaliar efeitos de inibidor da glicoproteína IIb/IIIa, cloridrato de tirofiban, nas alterações hepáticas e pulmonares ...
Leonardo F. Canedo, Marcel Autran C. Machado, Ana M. M. Coelho, Sandra N. Sampietre, Telesforo Bachella, Marcel C. C. Machado   +5 more
doaj   +1 more source

CAN3: BASELINE COST OF ILLNESS OF PARKINSON'S DISEASE IN A LARGE HEALTHCARE PLAN [PDF]

, 2000
We present a mixed finite element formulation for the spatial discretization in dynamic analysis of non-isothermal variably saturated porous media using different order of approximating functions for solid displacements and fluid pressures/temperature ...
Cao, Toan Duc, Sanavia, Lorenzo, Schrefler, B. A., Wang, Yongqi   +3 more
core   +1 more source

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2055-2067, October 2025.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source

Efficacy and Safety of Intracoronary versus Intravenous Administration of Tirofiban during Percutaneous Coronary Intervention for Acute Coronary Syndrome: A Meta-Analysis of Randomized Controlled Trials. [PDF]

PLoS ONE, 2015
Percutaneous coronary intervention (PCI) is known as the most effective treatment for acute coronary syndrome (ACS). However, without proper therapy and patient management, stent thrombosis after PCI may lead to another myocardial infarction. In addition
Xiuying Tang, Runjun Li, Quanmin Jing, Yingfeng Liu, Peng Liu   +4 more
doaj   +1 more source

Navigating the Uncertainties of Antithrombotic Therapy After Transcatheter Patent Foramen Ovale Closure: A Comprehensive Review

Catheterization and Cardiovascular Interventions, Volume 106, Issue 3, Page 2037-2047, September 1, 2025.
ABSTRACT The patent foramen ovale (PFO), present in 25% of the population, can cause paradoxical embolism and stroke. Transcatheter PFO closure is the gold standard for recurrent embolism with significant inter‐atrial shunting, with recent trials confirming its superiority in reducing ischemic stroke recurrence over medical therapy.
Eirini Beneki, Kyriakos Dimitriadis, Nikolaos Pyrpyris, Georgios Tzimas, Ioannis Skalidis, David Meier, Panagiotis Antiochos, Panagiotis Kostakis, Efthymia Pavlou, Francesco Perone, Georgios Tsivgoulis, Constantina Aggeli, Ole de Backer, Konstantinos Tsioufis   +13 more
wiley   +1 more source

Low-dose intravenous tirofiban infusion after endovascular recanalization for non-acute middle cerebral artery occlusion

Heliyon, 2022
Background and purpose: Endovascular recanalization for patients with symptomatic non-acute middle cerebral artery occlusion still remines challenging. Postoperative treatment is still controversial.
Zhang Xi, Chen Zhibin, Luo Yun, Duan Guangxin, Zhang He, Li Jingwei, Xu Yun   +6 more
doaj   +1 more source

Activity and Heterogeneity of Astrocytes in Neurological Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 6, Issue 9, September 2025.
Astrocytes display heterogeneity in various neurological disorders and behavioral neuropsychiatric disorders. Astrocytes influence the progression of neurological diseases through neuroinflammation, oxidative stress, metabolic abnormalities, intercellular interactions, and a spectrum of other pathophysiological processes.
Shijie Mao, Rui Qiao, Qi Wang, Ling Shen, Daxing Li, Xinchen Huo, Jindou Wang, Kunxuan Liu, Wenjing Chen, Tianhao Zhu, Beicheng Zhang, Shuo Leng, Ying Bai   +12 more
wiley   +1 more source

Adjunct Intraarterial or Intravenous Tirofiban Versus No Tirofiban After Successful Recanalization of Basilar Artery Occlusion Stroke: The BASILAR Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Approximately half of patients who achieve successful reperfusion do not achieve functional independence. The present study sought to investigate the clinical outcomes and safety of intraarterial or intravenous tirofiban as adjunct therapy in ...
Huagang Li, Dongsheng Ju, Zhaojun Tao, Jiayin Wang, Thanh N. Nguyen, Jeffrey L. Saver, Raul G. Nogueira, Chang Liu, Qingwu Yang, Zhongming Qiu, Congguo Yin, Dong Sun, Shudong Liu   +12 more
doaj   +1 more source