Results 71 to 80 of about 11,453 (268)

Effects of Periprocedural Tirofiban vs. Oral Antiplatelet Drug Therapy on Posterior Circulation Infarction in Patients With Acute Intracranial Atherosclerosis-Related Vertebrobasilar Artery Occlusion

Frontiers in Neurology, 2020
Background and purpose: Tirofiban and oral antiplatelet drugs can be used to inhibit reocclusion and restore microvascular reperfusion during endovascular treatment (EVT).
Xuan Sun, Huijun Zhang, Xu Tong, Feng Gao, Gaoting Ma, Zhongrong Miao   +5 more
doaj   +1 more source

There is no difference in safety and efficacy mechanical thrombectomy alone or mechanical thrombectomy with tirofiban for patients undergoing treatment of large vessel occlusion and underlying intracranial atherosclerosis

Interdisciplinary Neurosurgery, 2022
Background: Mechanical thrombectomy (MT) is a widely proven method to treat acute ischemic stroke (AIS) during mechanical thrombectomy and acute stenting and angioplasty is a topic discussed till this day regarding safety and efficacy.
Hari Movva, Rani Rabah, Wondwossen Tekle, Laurie Preston, Hari Kotta, Ameer E Hassan   +5 more
doaj   +1 more source

Administration of a Glycoprotein IIb/IIIa Receptor Blocker with a Thienopyridine Derivative Does Not Increase the Risk of Thrombocytopenia [PDF]

, 2005
Author Institution: Akron Cardiology Consulltants, OHAuthor Institution: Dept. of Educational Foundations & Leadership, University of Akron, OHAuthor Institution: Summa Health System, University of Akron, OHAuthor Institution: Dept.
Johnson, Jeremy, Josephson, Richard A., Newman, Isadore, Rohr, Susan M., Silver, Kevin H.   +4 more
core  

Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]

, 2005
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen, Heeschen C, James SK, Khaliq A, Luttun A, Mak KH   +5 more
core   +1 more source

Increased Thrombogenicity is Associated With Coronary Microvascular Dysfunction in Patients With STEMI—A Proof‐of‐Concept Study

Catheterization and Cardiovascular Interventions, Volume 106, Issue 2, Page 836-845, August 1, 2025.
ABSTRACT Background Up to 50% of patients with ST‐segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) develop coronary microvascular dysfunction (CMD). Aims This study aims to assess whether a prothrombotic state of coronary blood, defined by thromboelastography (TEG), is associated with post ...
Roberto Scarsini, Denis Leonardi, Andrea Bottardi, Concetta Mammone, Leonardo Portolan, Caterina Butturini, Verdiana Galli, Francesco Della Mora, Alessandro Ruzzarin, Sara Pazzi, Anna Piccoli, Simone Fezzi, Domenico Tavella, Gabriele Pesarini, Leonardo Gottin, Flavio Ribichini   +15 more
wiley   +1 more source

C-reactive protein binds to alphaIIbbeta3. [PDF]

, 2008
C-reactive protein binds to ...
Brennan, Marian P, Chubb, Anthony J, Cox, Dermot, Grennan, S, Moriarty, Roisin D   +4 more
core  

Evaluation of CYP2C19 Clinical Decision Support Alerts to Guide P2Y12 Inhibitor Prescribing

Clinical Pharmacology &Therapeutics, Volume 118, Issue 2, Page 470-479, August 2025.
P2Y12 inhibitor selection involves numerous factors, including CYP2C19 genetics, since evidence demonstrates reduced clopidogrel efficacy in patients with decreased or no function CYP2C19 variants. In 2020, Indiana University health embedded interruptive clinical decision support (CDS) alerts in the electronic health record (EHR) to recommend ...
Ashley N. Springer, Leah A. Alicea, Yemi Gafari, Tayler B. Smith, Sheryl Lynch, Amy M. Breman, Jennelle C. Hodge, Victoria M. Pratt, Nicholas R. Powell, Rolf P. Kreutz, Daniel P. Kobold, Michael T. Eadon, Emma M. Tillman, Tyler Shugg, Todd C. Skaar   +14 more
wiley   +1 more source

Subtyping treatment response of tirofiban in acute ischemic stroke based on neuroimaging features

Clinical and Translational Science
In a previously published clinical trial, we demonstrated that tirofiban was effective and safe in acute ischemic stroke (AIS) patients who did not undergo early recanalization treatments.
Bin Han, Xu Man, Jian Ding, Yuzhu Li, Xintao Tian, Xuelian Zhu, Jiang Yu, Jinping Sun   +7 more
doaj   +1 more source

Association Between Early Spontaneous Post‐Thrombectomy Blood Pressure Reduction and Clinical Outcomes in Large Vessel Occlusion Stroke

Brain and Behavior, Volume 15, Issue 7, July 2025.
Early spontaneous systolic blood pressure (SBP) reduction after thrombectomy—without pharmacologic intervention—was independently associated with favorable outcomes in patients with anterior circulation large vessel occlusion stroke. Combining ΔSBP with nadir SBP within 30 min post‐procedure significantly improved predictive accuracy for 90‐day ...
Jianwen Bu, Guosen Bu, Yang Zhang
wiley   +1 more source

Safety and Efficacy of Tirofiban During Mechanical Thrombectomy for Stroke Patients with Preceding Intravenous Thrombolysis

Clinical Interventions in Aging, 2020
Xiaochuan Huo,1,2,* Ming Yang,1,2,* Ning Ma,1,2 Feng Gao,1,2 Dapeng Mo,1,2 Xiaoqing Li,1,2 Anxin Wang,2,3 Yongjun Wang,2,3 Zhongrong Miao1,2 1Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, Beijing ...
Huo X, Yang M, Ma N, Gao F, Mo D, Li X, Wang A, Wang Y, Miao Z   +8 more
doaj