Results 221 to 230 of about 210,372 (257)
Some of the next articles are maybe not open access.
Cancer Research, 2023
Abstract Immunohistochemistry is the most widely used diagnostic technique in tissue pathology. However, IHC is associated with several limitations including the labeling of just a few markers per tissue section and limited quantification of cell populations.
Karen Kwarta +3 more
openaire +1 more source
Abstract Immunohistochemistry is the most widely used diagnostic technique in tissue pathology. However, IHC is associated with several limitations including the labeling of just a few markers per tissue section and limited quantification of cell populations.
Karen Kwarta +3 more
openaire +1 more source
Joining microelectronics and microionics: Nerve cells and brain tissue on semiconductor chips
ESSCIRC 2007 - 33rd European Solid-State Circuits Conference, 2007The direct electrical interfacing of semiconductor chips with individual nerve cells and with brain tissue is considered. At first, the structure of the cell-chip contact is described and then the electrical coupling is characterized between ion channels, the electrical elements of nerve cells, and transistors and capacitors of silicon chips.
openaire +3 more sources
Volume 3: Biomedical and Biotechnology Engineering, 2014
Physiological tissue-on-a-chip technology is enabled by adapting microfluidics to create micro scale drug screening platforms that replicate the complex drug transport and reaction processes in the human liver. The ability to incorporate three-dimensional (3d) tissue models using layered fabrication approaches into devices that can be perfused with ...
Filippos Tourlomousis, Robert C. Chang
openaire +1 more source
Physiological tissue-on-a-chip technology is enabled by adapting microfluidics to create micro scale drug screening platforms that replicate the complex drug transport and reaction processes in the human liver. The ability to incorporate three-dimensional (3d) tissue models using layered fabrication approaches into devices that can be perfused with ...
Filippos Tourlomousis, Robert C. Chang
openaire +1 more source
SSRN Electronic Journal, 2020
While periodontal (PD) disease is among principal causes of tooth loss worldwide, regulation of concomitant soft and mineralized PD tissues, and PD pathogenesis have not been completely clarified yet. Besides, relevant pre-clinical models and in vitro platforms have limitations in accurately simulating human physiology.
Murat Taner Vurat +5 more
openaire +1 more source
While periodontal (PD) disease is among principal causes of tooth loss worldwide, regulation of concomitant soft and mineralized PD tissues, and PD pathogenesis have not been completely clarified yet. Besides, relevant pre-clinical models and in vitro platforms have limitations in accurately simulating human physiology.
Murat Taner Vurat +5 more
openaire +1 more source
Fabrication of sac-like hydrogel membranes for replicating curved tissue barriers on chips
Lab on a ChipInspired by soap bubble formation, sac-like F127-DA hydrogel membranes that mimic real tissue barriers were created. It was used for the construction of a lung-on-a-chip device, successfully reproducing the pulmonary alveolar-capillary barrier.
Wenqi She +3 more
openaire +2 more sources
2022
The ever-growing need to understand and engineer biological and biochemical mechanisms of cells and materials that aim to study, restore, maintain, and improve the treatment of disease has led to the emergence of in vitro models in the field of tissue engineering.
openaire +1 more source
The ever-growing need to understand and engineer biological and biochemical mechanisms of cells and materials that aim to study, restore, maintain, and improve the treatment of disease has led to the emergence of in vitro models in the field of tissue engineering.
openaire +1 more source
On the Fabrication and Development of Tissue on a Chip Devices with Included Perfused Vasculatures
2019The advent of Tissue-on-a-Chip (TiOC) devices has provided a novel way for researchers to approach biological study and drug development. As a platform that enables human in vivo conditions to be accurately replicated ex vivo, TiOC can accelerate both fundamental biological research to answer basic questions regarding tissue behavior and function (e.g.,
openaire +2 more sources
Harnessing organs-on-a-chip to model tissue regeneration
Cell Stem Cell, 2021Gordana Vunjak-Novakovic +2 more
exaly
2013
The therapeutic potential of human pluripotent stem (hPS) cells is threatened by the difficulty to homogeneously direct cell differentiation into specific lineages. Aims: a) to efficiently derive mature hepatic cells from hPS cells; b) to integrate the specific lineages into a microfluidic platform to obtain a functional liver tissue on a chip. Methods:
GIOBBE, GIOVANNI GIUSEPPE +3 more
openaire +2 more sources
The therapeutic potential of human pluripotent stem (hPS) cells is threatened by the difficulty to homogeneously direct cell differentiation into specific lineages. Aims: a) to efficiently derive mature hepatic cells from hPS cells; b) to integrate the specific lineages into a microfluidic platform to obtain a functional liver tissue on a chip. Methods:
GIOBBE, GIOVANNI GIUSEPPE +3 more
openaire +2 more sources