Results 91 to 100 of about 9,392,969 (335)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Arbuscular mycorrhizal technology for the growth enhancement of micropropagated Spilanthes acmella Murr

open access: yesPlant Protection Science, 2012
Spilanthes acmella (Asteraceae) is an endangered ornamental cum medicinal annual herb. This study reports on the effect of two arbuscular mycorrhizal fungi (Glomus mosseae and Acaulospora laevis) applied either alone or in combination on post ...
Kuldeep YADAV   +2 more
doaj   +1 more source

Tissue culture of oil palm : finding the balance between mass propagation and somaclonal variation [PDF]

open access: yes, 2019
The oil palm (Elaeis guineensis Jacq.) is typically propagated in vitro by indirect somatic embryogenesis, a process in which somatic cells of an explant of choice are, via an intermediate phase of callus growth, induced to differentiate into somatic ...
Inzé, Dirk, Maene, Ludo, Weckx, Sylvie
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Addressing the Instability of DNA Nanostructures in Tissue Culture

open access: yesACS Nano, 2014
DNA nanotechnology is an advanced technique that could contribute diagnostic, therapeutic, and biomedical research devices to nanomedicine. Although such devices are often developed and demonstrated using in vitro tissue culture models, these conditions ...
Jaeseung Hahn   +3 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Development of In vitro Slow Growth Culture for Yam (Dioscorea alata L.)

open access: yesAnnals of Tropical Research, 2012
Germplasm collections, the lifeblood of breeding programs, are traditionally maintained in the field. Field genebanks are expensive, subject to genetic erosion, and require several quarantine measures for safe movement of genetic materials.
Villaluz Z. Acedo, Catherine C. Arradaza
doaj   +1 more source

Effects of FGFR inhibitors TKI258, BGJ398 and AZD4547 on breast cancer cells in 2D, 3D and tissue explant cultures [PDF]

open access: hybrid, 2020
Tiina E. Kähkönen   +12 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

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