Results 91 to 100 of about 1,285,350 (342)

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

Tissue culture: the unrealized potential [PDF]

open access: yesCytotechnology, 2007
Lack of differentiated functions of the tissue of origin in tissue culture thought to be due to dedifferentiation was shown to be due to selective overgrowth of fibroblasts. Enrichment culture techniques, (alternate animal and culture passage), designed to give the functionally differentiated cells selective advantage over the fibroblasts resulted in a
openaire   +2 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

GC–MS analysis underpins ethnomedicinal properties of Rhododendron flower brews from Singalila Himalaya highlighting the anticipated biosynthesis pathways of the bioactives

open access: yesDiscover Food
Guras or Rhododendron wine and its Raksi are popular and therapeutic traditional drinks served in the rhododendron growing regions of the Himalayas; mainly in northern and north eastern part of India, Nepal and Indo-Nepal Singalila ridge.
Soumya Majumder   +2 more
doaj   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Toxicity Effect of Silver Nanoparticles in Brine Shrimp Artemia

open access: yesThe Scientific World Journal, 2014
The present study revealed the toxic effect of silver nanoparticles (AgNPs) in Artemia nauplii and evaluated the mortality rate, hatching percentage, and genotoxic effect in Artemia nauplii/cysts.
Chinnasamy Arulvasu   +3 more
doaj   +1 more source

EFFECT OF AUXINE AND CYTOKININE ON CALLUS INDUCTION IN POTATO (SOLANUM TUBEROSUM L.) EXPLANTS

open access: yesAgricultura, 2009
Effect of growth regulators for callus induction of potato (Solanum tuberosum L.) genotypes (Christian and Roclas) was studied. The best callus induction was for MS medium supplemented with 1mg/L 2,4 D and 0,5 mg/l BAP for both the genotypes.
Andreea Nistor   +3 more
doaj   +1 more source

Rapid prediction of organisation in engineered corneal, glial and fibroblast tissues using machine learning and biophysical models [PDF]

open access: yesarXiv
We present a machine learning approach for predicting the organisation of corneal, glial and fibroblast cells in 3D cultures used for tissue engineering. Our machine-learning-based method uses a powerful generative adversarial network architecture called pix2pix, which we train using results from biophysical contractile network dipole orientation ...
arxiv  

Tissue Culture Models

open access: yes, 2009
The use of tissue cultures as a research tool to investigate the pathophysiological bases of diseases has become essential in the current ag of molecular biomedical research. Although it will always be necessary to translate and validate the observations seen in vitro to the patient or animal, the ability to investigate the role(s) of individual ...
Jeffrey M. Jordan   +3 more
openaire   +2 more sources

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