Results 111 to 120 of about 2,147,918 (389)
Novel design of biplanar electrodes in a multiwell plate for transepithelial electrical resistance measurement in 3D cell cultures [PDF]
Volume 387, 1 June 2025, 116413Recent advances in microphysiological systems have underscored the need for novel sensing and monitoring systems specifically designed for three-dimensional (3D) cell culture. In this article, an original architecture of a cell-culture multiwell plate embedding an impedance spectroscopy monitoring system is presented alongside a fast and ...
arxiv +1 more source
3D Printed TCP-Based Scaffold Incorporating VEGF-Loaded PLGA Microspheres for Craniofacial Tissue Engineering [PDF]
, 2017 Objective Vascularization is a critical process during bone regeneration/repair and the lack of tissue vascularization is recognized as a major challenge in applying bone tissue engineeringmethods for cranial and maxillofacial surgeries.
D. Lobner +7 more
core +2 more sources
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
A model of dissociated cortical tissue [PDF]
Proc. 7th Int. Workshop on Neural Coding, Montevideo, Uruguay,
Nov. 7-12, 2007, pp. 24-27, 2008 A powerful experimental approach for investigating computation in networks of biological neurons is the use of cultured dissociated cortical cells grown into networks on a multi-electrode array. Such preparations allow investigation of network development, activity, plasticity, responses to stimuli, and the effects of pharmacological agents.
arxiv
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Dorsal root ganglion neurons maintained in a 3D culture model exhibit similar electrophysiological properties to fresh explants [PDF]
, 2011 Tissue engineered culture models provide a powerful tool for neuroscience research1. They overcome limitations associated with monolayer cultures of neurons and glia by maintaining cells in a more realistic 3D spatial arrangement, and permit continuous ...
East, E., Murphy, K., Phillips, J.
core
Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]
, 2012 Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Weidenbusch, Marc, Anders, Hans-Joachim
core +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
TISSUE CULTURE STUDIES ON BACTERIAL HYPERSENSITIVITY [PDF]
, 1936 Johannes K. Moen, Homer F. Swift
openalex +3 more sources
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source