Results 71 to 80 of about 2,307,414 (336)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Tissue culture [PDF]

open access: yes, 2017
Activities of the tissue culture section of the Centro Internacional de Agricultura Tropical were focused on the improvement and utilization of meristem culture methods for disease eradication (frog skin), germplasm conservation and international ...
International Center for Tropical Agriculture
core  

Cardiac Specific Gene Expression Changes in Long Term Culture of Murine Mesenchymal Stem Cells [PDF]

open access: yes, 2011
Murine MSCs are a readily available source of adult stem cells enabling extensive in vitro study of this cell population. MSCs have been described as multipotent, and have been proven capable of differentiation into several connective tissue types ...
Argyle, D.J.   +6 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

In vitro propagation and DNA barcode analysis of the endangered Silene schimperiana in Saint Katherine protectorate

open access: yesJournal of Genetic Engineering and Biotechnology, 2020
Background Anthropogenic activity, climate change, pollution, and exploitation of natural resources are some reasons that cause threatening of plant diversity.
Heba El-Sayed Ghareb   +2 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Arbuscular mycorrhizal technology for the growth enhancement of micropropagated Spilanthes acmella Murr

open access: yesPlant Protection Science, 2012
Spilanthes acmella (Asteraceae) is an endangered ornamental cum medicinal annual herb. This study reports on the effect of two arbuscular mycorrhizal fungi (Glomus mosseae and Acaulospora laevis) applied either alone or in combination on post ...
Kuldeep YADAV   +2 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Fabrication, characterisation and performance of hydrophilic and super-hydrophilic silica as cell culture surfaces [PDF]

open access: yes, 2012
We demonstrate a straightforward procedure for the controlled formation of silica films on tissue culture polystyrene (PS) surfaces. The films were formed by sequentially treating PS with polyaniline, glutaric dialdehyde and protein prior to silica ...
Boocock, DJ   +4 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

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