Results 51 to 60 of about 2,255,345 (306)

Zero gravity tissue-culture laboratory [PDF]

, 1972
Hardware was developed for performing experiments to detect the effects that zero gravity may have on living human cells. The hardware is composed of a timelapse camera that photographs the activity of cell specimens and an experiment module in which a ...
Cook, J. E., Montgomery, P. O., Jr., Paul, J. S.   +2 more
core   +1 more source

A microfluidic chip based model for the study of full thickness human intestinal tissue using dual flow [PDF]

, 2016
© 2016 Author(s). The study of inflammatory bowel disease, including Ulcerative Colitis and Crohn's Disease, has relied largely upon the use of animal or cell culture models; neither of which can represent all aspects of the human pathophysiology ...
A. Dawson, Ananthakrishnan A. N., C. Dyer, Itzkowitz S. H., J. Davies, J. Greenman, J. Macfie, L. Karsai, M. Jacobsen, Ponder A., Rodrigues E., Triantafillidis J. K.   +11 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]

, 2012
Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Weidenbusch, Marc, Anders, Hans-Joachim
core   +3 more sources

Elevational adaptation and phenotypic plasticity of Codonopsis clematidea in the trans-Himalaya

Discover Plants
The process of adapting to changing environmental conditions plays a pivotal role in driving plant diversification. Elevational gradients provide a unique opportunity to investigate adaptation to diverse climatic conditions.
Zarina Khatoon, Seema Singh, Kanize Fatima, Mohd Ibrahim, Sajjad Ali, Sharada Mallubhotla   +5 more
doaj   +1 more source

Cell Line Monolayer Tissue Culture FKDL dan Cell Line OL sebagai Media Penumbuh Virus pada Pengembangan Bioteknologi Biomolekuler (Penelitian Eksperimental Laboratoris) [PDF]

, 2012
Cell line sangatlah penting dalam dunia medis, khususnya dibidang diagnosis, produksi vaksin maupun dibidang bioteknologi serta biomolekuler. Berbagai penelitian telah dilakukan untuk tehnik pembuatan Cell Line Monolayer Tissue Culture.
Hasdianah, H. (Hasdianah)
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Uncovering mercury accumulation and the potential for bacterial bioremediation in response to contamination in the Singalila National Park

Scientific Reports
Several recent investigations into montane regions have reported on excess mercury accumulation in high-altitude forest ecosystems. This study explored the Singalila National Park, located on the Singalila ridge of the Eastern Himalayas, revealing ...
Sukanya Acharyya, Soumya Majumder, Sudeshna Nandi, Arindam Ghosh, Sumedha Saha, Malay Bhattacharya   +5 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source