Results 51 to 60 of about 1,501,355 (317)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Production of colchicine by using plant cell culture [PDF]

open access: yes, 2005
Plant cell and tissue culture is an established alternative to the harvest and extraction of whole plant material for the production of valuable secondary metabolites.
Aroud, Gamal
core  

The influence of serum-free culture conditions on skeletal muscle differentiation in a tissue-engineered model [PDF]

open access: yes, 2008
The influence of differentiation medium (DM) components on C2C12 murine myoblast differentiation has only been studied in monolayer cultures. Serum-free formulations have been applied that omit the use of sera with unknown composition.
Baaijens, FPT Frank   +10 more
core   +1 more source

Harnessing in vitro technologies for conservation of Paeonia emodi, a threatened medicinal and ornamental species

open access: yesDiscover Plants
Paeonia emodi Wall. ex Royle, a valuable medicinal and ornamental species native to the north-western Himalayas, is threatened by overharvesting and habitat loss [1, 2].
Munisa Manzoor   +3 more
doaj   +1 more source

Gnotobiotic evaluation of Dalbergia sissoo genotypes for resistance against Fusarium solani via dual culture set up

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background Dalbergia sissoo (shisham), an important multipurpose tree native to the Indian subcontinent and also planted in other countries, has been afflicted with large scale mortality in all age groups due to wilt disease, causing huge economic losses.
Monika Chauhan   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Unfolding phenolics biosynthetic plasticity of Artemisia alba Turra through plant tissue culture techniques [PDF]

open access: yes
Artemisia alba Turra is an essential oil bearing plant, with Euro-Mediterranean and Southeastern European distribution. One of the distinctive characteristics of its essential oil is the variability of its terpenoid profile due to environmental, genetic ...
Todorova, Milka   +5 more
core   +1 more source

Elevational adaptation and phenotypic plasticity of Codonopsis clematidea in the trans-Himalaya

open access: yesDiscover Plants
The process of adapting to changing environmental conditions plays a pivotal role in driving plant diversification. Elevational gradients provide a unique opportunity to investigate adaptation to diverse climatic conditions.
Zarina Khatoon   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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