Results 41 to 50 of about 6,903,081 (310)

INCREASED OSMOLARITY AND CELL CLUSTERING PRESERVES CANINE NOTOCHORDAL CELL PHENOTYPE IN CULTURE [PDF]

open access: yes, 2013
Degeneration of the intervertebral disc (IVD) is associated with a loss of notochordal cells (NCs) from the nucleus pulposus (NP) and their replacement by chondrocyte-like cells.
Arkesteijn, I.   +11 more
core   +1 more source

Single ChAdOx1 nCoV‐19 dose elicits stronger immune response in previously infected individuals than in SARS‐CoV2 naive persons

open access: yesImmunity, Inflammation and Disease
Background Current vaccines against COVID‐19 effectively reduce morbidity and mortality and are vitally important for controlling the pandemic. Between December 2020 and February 2021, adenoviral vector vaccines such as ChAdOx1 (AstraZeneca‐Oxford) were ...
Fawzi Ebrahim   +11 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Harnessing in vitro technologies for conservation of Paeonia emodi, a threatened medicinal and ornamental species

open access: yesDiscover Plants
Paeonia emodi Wall. ex Royle, a valuable medicinal and ornamental species native to the north-western Himalayas, is threatened by overharvesting and habitat loss [1, 2].
Munisa Manzoor   +3 more
doaj   +1 more source

IN VITRO PRESERVATION OF DATE PALM (PHOENIX DACTYLIFERA L.) EMBRYOGENIC CALLUS [PDF]

open access: yesEgyptian Journal of Desert Research, 2014
In vitro medium term conservation of tropical plant germplasm is widely used for most plant species. Changes in the physical or chemical conditions had been used as a strategy for reducing the in vitro plant metabolism and prolonging the cultivation ...
Mohamed Diab   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Gnotobiotic evaluation of Dalbergia sissoo genotypes for resistance against Fusarium solani via dual culture set up

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background Dalbergia sissoo (shisham), an important multipurpose tree native to the Indian subcontinent and also planted in other countries, has been afflicted with large scale mortality in all age groups due to wilt disease, causing huge economic losses.
Monika Chauhan   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Variability in potato tissue culture

open access: yes, 1989
Tissue culture systems in potato (Solanum tuberosum L.) that involve a callus phase, such as regeneration of plants from protoplasts or expiants, can be accompanied by phenotypic variability, or somaclonal variation.
Bright, S. W. J.   +6 more
core   +1 more source

Elevational adaptation and phenotypic plasticity of Codonopsis clematidea in the trans-Himalaya

open access: yesDiscover Plants
The process of adapting to changing environmental conditions plays a pivotal role in driving plant diversification. Elevational gradients provide a unique opportunity to investigate adaptation to diverse climatic conditions.
Zarina Khatoon   +5 more
doaj   +1 more source

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