Results 111 to 120 of about 968,773 (372)

A Functional Human Liver Tissue Model: 3D Bioprinted Co-culture Discoids [PDF]

Biomaterials Advances, Volume 173, 2025, 214288
To reduce costs and delays related to developing new and effective drugs, there is a critical need for improved human liver tissue models. Here we describe an approach for 3D bioprinting functional human liver tissue models, in which we fabricate disc-shaped structures (discoids) 200 {\mu}m in thickness and 1-3 mm in diameter, embedded in a highly ...
arxiv   +1 more source

In vitro Culture of Several Rice Cultivars [PDF]

, 1989
Tissue culture methods have been established to regenerate certain rice (Oryza sativa L) cultivars, but regeneration of the rice cultivars widely grown in Arkansas has not been reported.
Al-Khayri, Jameel M., Dilday, R. H., Huang, Feng H., Mirlohi, A. F., Thompson, Lyell F.   +4 more
core   +2 more sources

Tissue culture: the unrealized potential [PDF]

, 2007
Lack of differentiated functions of the tissue of origin in tissue culture thought to be due to dedifferentiation was shown to be due to selective overgrowth of fibroblasts.
Sato, Gordon
core   +2 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Techniques in Plant Cell and Tissue Culture

, 1989
Publisher Summary Progress in refinement of techniques in the past several years has helped to establish tissue culture and cellular genetic manipulation as valuable tools for the development of new crops. This is an outgrowth of the first commercial use of tissue culture, which was the use of shoot tip propagation, as an alternative to conventional ...
openaire   +2 more sources

Advancements and future prospects in micropropagation techniques for major palm species: Date palm, oil palm, arecanut, and coconut [PDF]

Palms are widely distributed across warm temperate, tropical, and subtropical regions, showcasing their ecological significance and adaptability to diverse environments. Classification schemes play a crucial role in organizing the vast diversity of palms
keerthana, P, Manikanda, B N, Rajasree, V, Rajesh, S, Renuka, R, Suresh, J   +5 more
core   +2 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Tissue culture and biotechnological techniques applied to passion fruit with ornamental potential: an overview

Ornamental Horticulture, 2019
The ornamental flower sector has growing over the past years worldwide with potential for further expansion. Among the ornamental plants, Passiflora species have been gaining ground in the market, mainly in European and North American countries. However,
Andreia Izabel Mikosvki, Nayara Tayane Silva, Claudinei da Silva Souza, Marcelo Dias Machado, Wagner Campos Otoni, Ilio Fealho Carvalho, Diego Ismael Rocha, Maurecilne Lemes Silva   +7 more
doaj   +1 more source

Lattice and Continuum Modelling of a Bioactive Porous Tissue Scaffold

, 2018
A contemporary procedure to grow artificial tissue is to seed cells onto a porous biomaterial scaffold and culture it within a perfusion bioreactor to facilitate the transport of nutrients to growing cells.
Beliaev, Dmitry, Krause, Andrew L., Van Gorder, Robert A., Waters, Sarah L.   +3 more
core