Results 141 to 150 of about 968,773 (372)

Application of Plant Tissue Culture to the Propagation of Forest Trees [PDF]

open access: yes, 1977
Intensive culture of short rotation forest crops or the large scale replanting of forest land with selected, superior trees will depend on techniques for their practical, rapid, clonal, mass propagation.
Thompson, David G.
core   +2 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Tolerance Level of Butterfly Pea (Clitoria ternatea L.) to Stress Acidity Through Tissue Culture Technique [PDF]

open access: gold, 2023
Kennaya Putri Aura Jannah   +2 more
openalex   +1 more source

Concepts in marine biotechnology and their applications for enhancing aquaculture productivity [PDF]

open access: yes, 1991
Application of biotechnology techniques to agriculture increased the quality and quantity of the final yield. Genetic engineering applied to the production of fish, molluscs and crustaceans although at the rudimentary stage offers promise.
James, P S B R, Ponniah, A G
core  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Sample preparation and data collection for serial block face scanning electron microscopy of mammalian cell monolayers.

open access: yesPLoS ONE
Volume electron microscopy encompasses a set of electron microscopy techniques that can be used to examine the ultrastructure of biological tissues and cells in three dimensions.
Noelle V Antao   +5 more
doaj   +1 more source

Self-Pluralising Culture Alignment for Large Language Models [PDF]

open access: yesarXiv
As large language models (LLMs) become increasingly accessible in many countries, it is essential to align them to serve pluralistic human values across cultures. However, pluralistic culture alignment in LLMs remain an open problem. In this paper, we propose CultureSPA, a Self-Pluralising Culture Alignment framework that allows LLMs to simultaneously ...
arxiv  

Towards systems tissue engineering: elucidating the dynamics, spatial coordination, and individual cells driving emergent behaviors [PDF]

open access: yesarXiv, 2019
Biomaterial systems have allowed for the in vitro production of complex, emergent tissue behaviors that were not possible with conventional 2D culture systems allowing for analysis of the normal development as well as disease processes. We propose that the path towards developing the design parameters for biomaterial systems lies with identifying the ...
arxiv  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

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