Results 11 to 20 of about 12,729,869 (376)

Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic Mechanisms

open access: yesACS Chemical Neuroscience, 2020
The recent outbreak of coronavirus infectious disease 2019 (COVID-19) has gripped the world with apprehension and has evoked a scare of epic proportion regarding its potential to spread and infect humans worldwide.
A. Baig   +3 more
semanticscholar   +1 more source

Computational fluid dynamic analysis of bioprinted self-supporting perfused tissue models [PDF]

open access: yes, 2020
Natural tissues are incorporated with vasculature, which is further integrated with a cardiovascular system responsible for driving perfusion of nutrient‐rich oxygenated blood through the vasculature to support cell metabolism within most cell‐dense ...
Bonewald, Lynda F.   +8 more
core   +1 more source

Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease

open access: yesFrontiers in Cardiovascular Medicine, 2020
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date several types of adipose tissue have been identified, namely white, brown, and beige, that reside in various specific anatomical locations throughout the body. The
A. Chait, Laura J. den Hartigh
semanticscholar   +1 more source

Advances in Exosome-Based Drug Delivery and Tumor Targeting: From Tissue Distribution to Intracellular Fate

open access: yesInternational Journal of Nanomedicine, 2020
Exosomes or small extracellular vesicles are considered a new generation of bioinspired-nanoscale drug delivery system (DDS). Endogenous exosomes function as signalosomes since they convey signals via ligands or adhesion molecules located on the exosomal
J. Shao, J. Zaro, Yuxian Shen
semanticscholar   +1 more source

Study on Absorption Mechanism and Tissue Distribution of Fucoidan

open access: yesMolecules, 2020
Fucoidan exhibits several pharmacological activities and is characterized by high safety and the absence of toxic side effects. However, the absorption of fucoidan is not well-characterized.
Xu Bai   +5 more
semanticscholar   +1 more source

Antiviral effects and tissue exposure of tetrandrine against SARS‐CoV‐2 infection and COVID‐19

open access: yesMedComm, 2023
Tetrandrine (TET) has been used to treat silicosis in China for decades. The aim of this study was to facilitate rational repurposing of TET against SARS‐CoV‐2 infection. In this study, we confirmed that TET exhibited antiviral potency against SARS‐CoV‐2
Jia Liu   +18 more
doaj   +1 more source

A Pyridazinone Compound for Effectively Treating Non-alcoholic Steatohepatitis by Targeting THRβ

open access: yesFrontiers in Chemistry, 2022
Developing effective therapies and medicines to conquer nonalcoholic steatohepatitis (NASH) is of great significance for public health and is faced with a major challenge.
Hao Cheng   +19 more
doaj   +1 more source

Effects of Huangqi Liuyi Decoction in the Treatment of Diabetic Nephropathy and Tissue Distribution Difference of its Six Active Constituents Between Normal and Diabetic Nephropathy Mouse Models

open access: yesFrontiers in Pharmacology, 2022
The purpose of this study was to investigate the effects of Huangqi Liuyi decoction extract (HQD) on diabetic nephropathy (DN), and the tissue distribution difference of six main active ingredients of HQD between normal and DN mouse models.
Qun Wang   +7 more
doaj   +1 more source

Effects of ultra-purified polymerized bovine hemoglobin on local tissue oxygen tension in striated skin muscle - An efficacy study in the hamster [PDF]

open access: yes, 2002
The development of hemoglobin-based oxygen carriers has been propagated for replacement of the oxygen carrying properties of red blood cells for almost one century.
Botzlar, Andreas   +2 more
core   +1 more source

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