Results 111 to 120 of about 6,837,049 (299)

Carbon based materials in conducting tissue engineering

Materials Research Express
Conducting materials based on carbon have been widely investigated in conducting tissue engineering applications due to their outstanding physical, chemical, thermal, and electric properties in recent years. Carbon based conductive materials can generate
Elif Sancar, Büşra Oktay, Esma Ahlatcıoğlu Özerol   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Tissue engineering. Part C: Methods.

Ten dele voortzetting van: Tissue engineering [ISSN 1076 ...
Tissue engineering and regenerative medicine international society
core  

Growth factors upregulate deposition and remodeling of ECM by endothelial cells cultured for tissue-engineering applications

, 2007
Appropriate matrix formation, turnover and remodeling in tissue-engineered small diameter vascular conduits are crucial for their long-term function. The interaction between cells and extra-cellular components is indispensable in determining cellular ...

core   +1 more source

Short-term stress preconditioning activates sympathetic innervation in the testes to mitigate testicular ischemia-reperfusion injury

Journal of Neuroinflammation
Testicular tissues are highly vulnerable to oxidative stress and external insults due to their unique physiological microenvironment; thus, developing protective interventions is critical.
Liyong Liu, Ruiming Xu, Heshe Li, Yuanchen Ma, Yue Shu, Hongjie Liang, Tao Wang, Jiang Hao, Weiqiang Li, Andy Peng Xiang, Mei Hua Jiang, Weijun Huang   +11 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Non-alcoholic beverages, unknown influence on cell proliferation – an [i]in vitro[/i] study

Annals of Agricultural and Environmental Medicine, 2014
Introduction and objective. The aim of the presented study was to check differences between ‘Diet’ and ‘non-Diet’ soft drinks on cell proliferation. Materials and methods.
Maciej Nowacki, Jan Adamowicz, Joanna Olkowska, Katarzyna Pietkun, Tomasz Kloskowski, Anna Bajek, Tomasz Drewa   +6 more
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Nanozyme-Engineered Hydrogels for Anti-Inflammation and Skin Regeneration

Nano-Micro Letters
Highlights Nanozyme-based approaches to produce therapeutic hydrogels. Enzymatic mechanisms and multifunctional roles of nanozyme-engineered hydrogels for skin therapy.
Amal George Kurian, Rajendra K. Singh, Varsha Sagar, Jung-Hwan Lee, Hae-Won Kim   +4 more
doaj   +1 more source