Results 1 to 10 of about 48,034 (155)
In vivo cartilage tissue engineering [PDF]
Journal of Orthopaedic Surgery and Research, 2018 Background Biologic treatment options for cartilage injuries require chondrocyte expansion using cell culture. Clinical application is accomplished in two surgical sessions and is expensive. If isolation of chondrocytes and stimulus for proliferation and
B. Gurer +4 more
doaj +4 more sources
Engineering cartilage tissue [PDF]
Advanced Drug Delivery Reviews, 2008 Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it is essential to develop approaches that deliver the appropriate cells, biomaterials, and signaling factors to the defect site.
Jason Burdick, Cindy Chung
exaly +3 more sources
Artificial Cells, Nanomedicine, and Biotechnology, 2020 Many traditional procedures, including surgical methods such as microfracture of subchondral bone and soft tissue transplantation, have been widely used to treat damaged cartilage. However, there is still no definitive cure for cartilage defects.
Azizeh Rahmani Del Bakhshayesh +5 more
doaj +3 more sources
Electrical Stimulation in Cartilage Tissue Engineering
Bioengineering, 2023 Electrical stimulation (ES) has been frequently used in different biomedical applications both in vitro and in vivo. Numerous studies have demonstrated positive effects of ES on cellular functions, including metabolism, proliferation, and differentiation.
Raminta Vaiciuleviciute +5 more
doaj +4 more sources
Tissue Engineering: An Alternative to Repair Cartilage
Tissue Engineering - Part B: Reviews, 2019 Herein we review the state-of-the-art in tissue engineering for repair of articular cartilage. First, we describe the molecular, cellular, and histologic structure and function of endogenous cartilage, focusing on chondrocytes, collagens, extracellular matrix, and proteoglycans.
Luis Javier Cruz +2 more
exaly +7 more sources
Designing functional hyaluronic acid-based hydrogels for cartilage tissue engineering
Materials Today Bio, 2022 Damage to cartilage tissues is often difficult to repair owing to chronic inflammation and a lack of bioactive factors. Therefore, developing bioactive materials, such as hydrogels acting as extracellular matrix mimics, that can inhibit the inflammatory ...
Min Wang, Zexing Deng, Yi Guo, Peng Xu
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Although there have been remarkable advances in cartilage tissue engineering, construction of irregularly shaped cartilage, including auricular, nasal, tracheal, and meniscus cartilages, remains challenging because of the difficulty in reproducing its ...
Hui Wang +12 more
doaj +1 more source
Cartilaginous Organoids: Advances, Applications, and Perspectives
Advanced NanoBiomed Research, 2023 Cartilage is a nonvascular and non‐neural, mesoderm‐derived tissue. Cartilage repair, especially articular cartilage repair and reconstruction, has always been a difficult problem in bone tissue engineering.
Yuhao Yu +4 more
doaj +1 more source
Function and Mechanism of RGD in Bone and Cartilage Tissue Engineering
Frontiers in Bioengineering and Biotechnology, 2021 Bone and cartilage injury is common, tissue engineered scaffolds are potential means to repair. Because most of the scaffold materials used in bone and cartilage tissue engineering are bio-inert, it is necessary to increase the cellular adhesion ability ...
Meng Yang +16 more
doaj +1 more source
Tissue engineering and cartilage [PDF]
Organogenesis, 2008 Human articular cartilage is an avascular structure, which, when injured, poses significant hurdles to repair strategies. Not only does the defect need to be repopulated with cells, but preferentially with hyaline-like cartilage.SUCCESSFUL TISSUE ENGINEERING RELIES ON FOUR SPECIFIC CRITERIA: cells, growth factors, scaffolds, and the mechanical ...
Michael W, Kessler, Daniel A, Grande
openaire +2 more sources