Strain stiffening universality in composite hydrogels and soft tissues [PDF]
Soft biological tissues exhibit a remarkable resilience to large mechanical loads, a property which is associated with the strain stiffening capability of the biopolymer networks that structurally support the tissues. Yet, recent studies have shown that composite systems such as tissues and blood clots exhibit mechanical properties that contradict ...
arxiv
Microscopic biophysical model of self-organization in tissue due to feedback between cell- and macroscopic-scale forces [PDF]
We develop a microscopic biophysical model for self-organization and reshaping of artificial tissue, that is co-driven by microscopic active forces between cells and extracellular matrix (ECM), and macroscopic forces that develop within the tissue, finding close agreement with experiment.
arxiv +1 more source
Tissue Engineering of Skin Regeneration and Hair Growth [PDF]
Many people suffering from skin disorders such as chronic wounds, non-healing ulcers, and diabetic ulcers need skin repair and regeneration. Aside from the diseases listed above, the industry needed a skin rejuvenation system and regeneration for cosmetic purposes.
arxiv
Readout of fluorescence functional signals through highly scattering tissue [PDF]
Fluorescence is a powerful mean to probe information processing in the mammalian brain. However, neuronal tissues are highly heterogeneous and thus opaque to light. A wide set of non-invasive or invasive techniques for scattered light rejection, optical sectioning or localized excitation, have been developed, but non-invasive optical recording of ...
arxiv +1 more source
Tumor microenvironment (Part I): Tissue integrity in a rat model of peripheral neural cancer [PDF]
ICAM-1 (intercellular adhesion molecule 1) and MPZ (myelin protein zero) are thought to be a factor in the integrity of nerve tissues. In this report, we attempted to trace the expression of ICAM-1, responsible for cell-to-cell adhesion, and of MPZ, the main constituent of myelin sheath, in malignant tissues of the sciatic nerve (SN) in inbred male ...
arxiv +1 more source
ScarGAN: Chained Generative Adversarial Networks to Simulate Pathological Tissue on Cardiovascular MR Scans [PDF]
Medical images with specific pathologies are scarce, but a large amount of data is usually required for a deep convolutional neural network (DCNN) to achieve good accuracy. We consider the problem of segmenting the left ventricular (LV) myocardium on late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) scans of which only some of ...
arxiv
Studying Therapy Effects and Disease Outcomes in Silico using Artificial Counterfactual Tissue Samples [PDF]
Understanding the interactions of different cell types inside the immune tumor microenvironment (iTME) is crucial for the development of immunotherapy treatments as well as for predicting their outcomes. Highly multiplexed tissue imaging (HMTI) technologies offer a tool which can capture cell properties of tissue samples by measuring expression of ...
arxiv
FACTORS OF RESISTANCE TO HETEROPLASTIC TISSUE-GRAFTING [PDF]
James B. Murphy
openalex +1 more source
Particle diffusion in extracellular hydrogels [PDF]
Hyaluronic acid is an abundant polyelectrolyte in the human body that forms extracellular hydrogels in connective tissues. It is essential for regulating tissue biomechanics and cell-cell communication, yet hyaluronan overexpression is associated with pathological situations such as cancer and multiple sclerosis.
arxiv
TISSUE PERMEABILITY AND THE SPREADING FACTORS IN INFECTION [PDF]
F. DuranâReynals
openalex +1 more source