Results 11 to 20 of about 17,692,743 (361)

Advances in Growth Factor Delivery for Bone Tissue Engineering

open access: yesInternational Journal of Molecular Sciences, 2021
Shortcomings related to the treatment of bone diseases and consequent tissue regeneration such as transplants have been addressed to some extent by tissue engineering and regenerative medicine. Tissue engineering has promoted structures that can simulate
É. R. Oliveira   +6 more
semanticscholar   +1 more source

Tissue Factor Deficiency

open access: yesDefinitions, 2020
coagulation by the partial or complete absence of tissue ...

semanticscholar   +1 more source

Vitamin D Inhibits IL-6 Pro-Atherothrombotic Effects in Human Endothelial Cells: A Potential Mechanism for Protection against COVID-19 Infection?

open access: yesJournal of Cardiovascular Development and Disease, 2022
Background: Thrombosis with cardiovascular involvement is a crucial complication in COVID-19 infection. COVID-19 infects the host by the angiotensin converting enzyme-2 receptor (ACE2r), which is expressed in endothelial cells too.
Giovanni Cimmino   +9 more
doaj   +1 more source

Thrombogenic and Inflammatory Reactions to Biomaterials in Medical Devices

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Blood-contacting medical devices of different biomaterials are often used to treat various cardiovascular diseases. Thrombus formation is a common cause of failure of cardiovascular devices.
Carlos A. Labarrere   +2 more
doaj   +1 more source

Tissue factor potentiates adherence of breast cancer cells to human umbilical vein endothelial cells under static and flow conditions

open access: yesCell Adhesion & Migration, 2021
Tissue factor (TF) has been extensively studied for tumor metastasis, but its role in mediating cancer cell adhesion to vasculature remains unknown. This study aimed to measure the ability of TF to mediate the adhesion of breast cancer cells to human ...
Yanling Jin   +9 more
doaj   +1 more source

Tissue factor controversies [PDF]

open access: yesThrombosis Research, 2012
Tissue factor plays a primary role in both hemorrhage control and thrombosis depending upon whether its presentation is extravascular or intravascular. The molecular architecture and function of the tissue factor molecule and its role in the activations of factor IX and factor X have been elegantly elucidated but controversies prevail with respect to ...
Kenneth G. Mann   +2 more
openaire   +3 more sources

The role of tissue factor in normal pregnancy and in the development of preeclampsia: A review

open access: yesBiomedical Papers, 2015
Background: Tissue factor (TF) is a key element for normal gestation, especially in the first trimester. TF levels are hence raised in pregnancy, producing an adaptive hypercoagulable state.
Jana Prochazkova   +3 more
doaj   +1 more source

Transforming growth factor–β in tissue fibrosis

open access: yesJournal of Experimental Medicine, 2020
TGF-β is a central mediator in the fibrotic response. This review discusses the role of TGF-β in tissue fibrosis, highlighting the mechanisms of TGF-β activation and signaling, the cellular targets of TGF-β actions, and the challenges of therapeutic ...
N. Frangogiannis
semanticscholar   +1 more source

Heparanase and Coagulation–New Insights

open access: yesRambam Maimonides Medical Journal, 2014
Heparanase, a β-D-endoglucuronidase abundant in platelets that was discovered 30 years ago, is an enzyme that cleaves heparan sulfate side chains on the cell surface and in the extracellular matrix. It was later recognized as being a pro-inflammatory and
Yona Nadir
doaj   +1 more source

Tissue factor as a potential coagulative/vascular marker in relapsing-remitting multiple sclerosis

open access: yesFrontiers in Immunology, 2023
ObjectivesRecent studies supported coagulation involvement in multiple sclerosis, an inflammatory-demyelinating and degenerative disease of the central nervous system. The main objectives of this observational study were to identify the most specific pro-
Tatiana Koudriavtseva   +21 more
doaj   +1 more source

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