Results 261 to 270 of about 3,940,286 (283)
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Thrombosis and Haemostasis, 1999
Cell Biology of Tissue Factor Transmembrane receptor tissue factor (TF) initiates the coagulation pathways by serving as the cofactor for coagulation factor VIIa.1 The extracellular domain of TF consists of two fibronectin-type III modules in the orientation of a typical class II cytokine receptor extracellular domain,2 confirming the earlier ...
W, Ruf, B M, Mueller
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Cell Biology of Tissue Factor Transmembrane receptor tissue factor (TF) initiates the coagulation pathways by serving as the cofactor for coagulation factor VIIa.1 The extracellular domain of TF consists of two fibronectin-type III modules in the orientation of a typical class II cytokine receptor extracellular domain,2 confirming the earlier ...
W, Ruf, B M, Mueller
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Best Practice & Research Clinical Haematology, 1999
Blood coagulation is initiated in response to vessel damage in order to preserve the integrity of the mammalian vascular system. The coagulation cascade can also be initiated by mediators of the inflammatory response, and fibrin deposition has been noted in a variety of pathological states.
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Blood coagulation is initiated in response to vessel damage in order to preserve the integrity of the mammalian vascular system. The coagulation cascade can also be initiated by mediators of the inflammatory response, and fibrin deposition has been noted in a variety of pathological states.
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Pathophysiology of Haemostasis and Thrombosis, 2007
Tissue factor (TF), the key regulator of haemostasis and angiogenesis, is also involved in the pathology of several diseases, including cardiovascular, inflammatory and neoplastic conditions. In the latter, TF is upregulated by cancer cells, as well as by certain host cells, and it is the interactions between these distinct pools of TF-expressing cells
Chloe, Milsom, Janusz, Rak
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Tissue factor (TF), the key regulator of haemostasis and angiogenesis, is also involved in the pathology of several diseases, including cardiovascular, inflammatory and neoplastic conditions. In the latter, TF is upregulated by cancer cells, as well as by certain host cells, and it is the interactions between these distinct pools of TF-expressing cells
Chloe, Milsom, Janusz, Rak
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Tissue factor in atherosclerosis
Atherosclerosis, 1999Thrombosis is a key feature of the initiation and progression of atherosclerosis and its clinical sequelae. Acute thrombosis can lead to arterial occlusion and consequently provoke myocardial infarction, unstable angina, stroke and sudden death. Acute thrombosis can also be a complication of arterial bypass surgery, balloon angioplasty, atherectomy, or
E. Tremoli +3 more
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Seminars in Thrombosis and Hemostasis, 2006
Tissue factor (TF) exhibits a distinct nonuniform tissue distribution. Thus, high levels are found in highly vascularized organs such as the lung, brain, and placenta; intermediate levels in the heart, kidney, intestine, testes, and uterus; and low levels in the spleen, thymus, and liver.
Bjarne, Østerud, Eirik, Bjørklid
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Tissue factor (TF) exhibits a distinct nonuniform tissue distribution. Thus, high levels are found in highly vascularized organs such as the lung, brain, and placenta; intermediate levels in the heart, kidney, intestine, testes, and uterus; and low levels in the spleen, thymus, and liver.
Bjarne, Østerud, Eirik, Bjørklid
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The international journal of biochemistry & cell biology, 1998
Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer. However, recent evidence has accumulated that tissue factor may have functions beyond controlling fibrin-dependent ...
P, Carmeliet, D, Collen
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Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer. However, recent evidence has accumulated that tissue factor may have functions beyond controlling fibrin-dependent ...
P, Carmeliet, D, Collen
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Tissue factor and cardiomyocytes
Thrombosis Research, 2012Tissue factor, the initiator of blood coagulation, plays a major role in the protection of several organs against bleeding. Cardiomyocytes and fibroblasts constitutively express tissue factor. Besides its role for maintain cardiac hemostasis TF has been suggested to have several other important functions in the cardiac muscle.
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Current Opinion in Hematology, 2008
Tissue factor is increasingly viewed as an integral part of the vicious circle that links the vascular system with cancer progression at multiple systemic, cellular and molecular levels.The emerging tenet in this area is that oncogenic events/pathways driving the malignant process also stimulate the expression of tissue factor by cancer cells and ...
Janusz, Rak, Chloe, Milsom, Joanne, Yu
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Tissue factor is increasingly viewed as an integral part of the vicious circle that links the vascular system with cancer progression at multiple systemic, cellular and molecular levels.The emerging tenet in this area is that oncogenic events/pathways driving the malignant process also stimulate the expression of tissue factor by cancer cells and ...
Janusz, Rak, Chloe, Milsom, Joanne, Yu
openaire +2 more sources