Results 261 to 270 of about 8,614,068 (306)

Cryo-EM structure of the tissue factor/factor VIIa complex with a factor X mimetic reveals a novel allosteric mechanism. [PDF]

open access: yesBlood
Sedzro JC   +11 more
europepmc   +1 more source

Associations of tissue factor and tissue factor pathway inhibitor with organ dysfunctions in septic shock. [PDF]

open access: yesSci Rep
Lehner GF   +9 more
europepmc   +1 more source
Some of the next articles are maybe not open access.

Related searches:

Tissue Factor Signaling

Thrombosis and Haemostasis, 1999
Cell Biology of Tissue Factor Transmembrane receptor tissue factor (TF) initiates the coagulation pathways by serving as the cofactor for coagulation factor VIIa.1 The extracellular domain of TF consists of two fibronectin-type III modules in the orientation of a typical class II cytokine receptor extracellular domain,2 confirming the earlier ...
W, Ruf, B M, Mueller
openaire   +2 more sources

Tissue Factor on the Loose

Seminars in Thrombosis and Hemostasis, 2000
The enzymatic complex of tissue factor (TF) and the blood coagulation factor VIIa is generally considered to be the initiator of coagulation. Coagulation that occurs at the site of luminal injury to an artery is, along with platelet deposition, the cause of arterial thrombosis, which is the leading cause of death in Western society.
P L, Giesen, Y, Nemerson
openaire   +2 more sources

Sources of Tissue Factor

Seminars in Thrombosis and Hemostasis, 2006
Tissue factor (TF) exhibits a distinct nonuniform tissue distribution. Thus, high levels are found in highly vascularized organs such as the lung, brain, and placenta; intermediate levels in the heart, kidney, intestine, testes, and uterus; and low levels in the spleen, thymus, and liver.
Bjarne, Østerud, Eirik, Bjørklid
openaire   +2 more sources

Tissue Factor pathway

Best Practice & Research Clinical Haematology, 1999
Blood coagulation is initiated in response to vessel damage in order to preserve the integrity of the mammalian vascular system. The coagulation cascade can also be initiated by mediators of the inflammatory response, and fibrin deposition has been noted in a variety of pathological states.
openaire   +7 more sources

Tissue factor in atherosclerosis

Atherosclerosis, 1999
Thrombosis is a key feature of the initiation and progression of atherosclerosis and its clinical sequelae. Acute thrombosis can lead to arterial occlusion and consequently provoke myocardial infarction, unstable angina, stroke and sudden death. Acute thrombosis can also be a complication of arterial bypass surgery, balloon angioplasty, atherectomy, or
E. Tremoli   +3 more
openaire   +2 more sources

Tissue Factor and Cancer

Pathophysiology of Haemostasis and Thrombosis, 2007
Tissue factor (TF), the key regulator of haemostasis and angiogenesis, is also involved in the pathology of several diseases, including cardiovascular, inflammatory and neoplastic conditions. In the latter, TF is upregulated by cancer cells, as well as by certain host cells, and it is the interactions between these distinct pools of TF-expressing cells
Chloe, Milsom, Janusz, Rak
openaire   +2 more sources

Tissue factor in cancer

Current Opinion in Hematology, 2008
Tissue factor is increasingly viewed as an integral part of the vicious circle that links the vascular system with cancer progression at multiple systemic, cellular and molecular levels.The emerging tenet in this area is that oncogenic events/pathways driving the malignant process also stimulate the expression of tissue factor by cancer cells and ...
Janusz, Rak, Chloe, Milsom, Joanne, Yu
openaire   +2 more sources

Home - About - Disclaimer - Privacy