Results 1 to 10 of about 599,590 (294)

Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation [PDF]

Redox Biology, 2023
Tissue factor pathway inhibitor (TFPI) is an important regulator of coagulation and a link between inflammation and thrombosis. Here we investigated whether endothelial cell-driven oxidative post-translational modifications could have an impact on TFPI ...
Janina Wittig, Maria-Kyriaki Drekolia, Anastasia Kyselova, Fredy Delgado Lagos, Magdalena L. Bochenek, Jiong Hu, Katrin Schäfer, Ingrid Fleming, Sofia-Iris Bibli   +8 more
doaj   +2 more sources

MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium [PDF]

Scientific Reports, 2022
A large portion of the genome is transcribed into non-coding RNA, which does not encode protein. Many long non-coding RNAs (lncRNAs) have been shown to be involved in important regulatory processes such as genomic imprinting and chromatin modification ...
Veerle Kremer, Diewertje I. Bink, Laura Stanicek, Eva van Ingen, Theresa Gimbel, Sarah Hilderink, Stefan Günther, Anne Yaël Nossent, Reinier A. Boon   +8 more
doaj   +2 more sources

Extracellular vesicle tissue factor and tissue factor pathway inhibitor are independent discriminators of sepsis-induced coagulopathy [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: Sepsis-induced disseminated intravascular coagulopathy (DIC) remains a challenging clinical entity associated with significant morbidity and mortality.
Anna K. Tobiasch, Georg F. Lehner, Clemens Feistritzer, Andreas Peer, Birgit Zassler, Viktoria M. Neumair, Sebastian J. Klein, Michael Joannidis   +7 more
doaj   +2 more sources

Associations of tissue factor and tissue factor pathway inhibitor with organ dysfunctions in septic shock [PDF]

Scientific Reports
Coagulopathy, microvascular alterations and concomitant organ dysfunctions are hallmarks of sepsis. Attempts to attenuate coagulation activation with an inhibitor of tissue factor (TF), i.e.
Georg Franz Lehner, Anna Katharina Tobiasch, Fabian Perschinka, Timo Mayerhöfer, Markus Waditzer, Viktoria Haller, Birgit Zassler, Sarah Maier, Hanno Ulmer, Michael Joannidis   +9 more
doaj   +2 more sources

Tissue factor pathway inhibitor upregulates CXCR7 expression and enhances CXCL12-mediated migration in chronic lymphocytic leukemia [PDF]

Scientific Reports, 2021
The infiltration of chronic lymphocytic leukemia (CLL) cells into lymphoid organs correlates with disease severity. CXCL12 is a key chemotactic factor for the trafficking of CLL.
Xue Yan Cui, Geir Erland Tjønnfjord, Sandip M. Kanse, Anders Erik Astrup Dahm, Nina Iversen, Christiane Filion Myklebust, Ling Sun, Zhong Xing Jiang, Thor Ueland, James J. Campbell, Mitchell Ho, Per Morten Sandset   +11 more
doaj   +2 more sources

Tissue factor pathway inhibitor 2 (TFPI2) is a potential serum biomarker for clear cell renal carcinoma [PDF]

Scientific Reports
Renal and ovarian clear cell carcinoma (CCC) are both characterized by a clear cytoplasm and exhibit similar genomic alterations and clinical characteristics. We hypothesized that both CCCs may share clinical biomarker. Tissue factor pathway inhibitor 2 (
Hiroki Ito, Ryosuke Jikuya, Shohei Myoba, Tomoyuki Tatenuma, Go Noguchi, Daiki Ueno, Yusuke Ito, Mitsuru Komeya, Kentaro Muraoka, Masahiro Yao, Hisashi Hasumi, Noboru Nakaigawa, Kazuhide Makiyama   +12 more
doaj   +2 more sources

Tissue factor pathway inhibitor‑2 is specifically expressed in ovarian clear cell carcinoma tissues in the nucleus, cytoplasm and extracellular matrix. [PDF]

Oncol Rep, 2021
Ota Y, Koizume S, Nakamura Y, Yoshihara M, Takahashi T, Sato S, Myoba S, Ohtake N, Kato H, Yokose T, Miyagi E, Miyagi Y.   +11 more
europepmc   +3 more sources

Tissue factor pathway inhibitor 2 as a serum biomarker for endometrial cancer: a single-center retrospective study [PDF]

BMC Cancer
Background Endometrial cancer is the most common gynecological malignancy; however, there is no useful blood diagnostic biomarker. This study aimed to determine the utility of tissue factor pathway inhibitor 2 (TFPI2), a biomarker of ovarian cancer, as a
Mari Uomoto, Yukihide Ota, Yukio Suzuki, Asuna Yumori, Hiroto Narimatsu, Shiro Koizume, Shinya Sato, Yoshiyasu Nakamura, Shohei Myoba, Norihisa Ohtake, Haruya Saji, Etsuko Miyagi, Yohei Miyagi   +12 more
doaj   +2 more sources

Preoperative serum tissue factor pathway inhibitor‑2 level as a prognostic marker for endometrial cancer. [PDF]

Oncol Lett, 2023
Kawaguchi R, Maehana T, Yamanaka S, Miyake R, Kawahara N, Iwai K, Yamada Y, Kimura F.   +7 more
europepmc   +3 more sources

Tissue Factor Pathway Inhibitor

Japanese Journal of Thrombosis and Hemostasis, 1991
Tatsuya HAYASHI, Koji SUZUKI
openaire   +3 more sources