Histology of the whole body of honey bees: tissue fixation and processing. [PDF]
J Vet Diagn Invest, 2023 Lussier J +2 more
europepmc +1 more source
COMPLEMENT FIXATION IN DISEASED TISSUES [PDF]
The Journal of Experimental Medicine, 1961 An immunohistologic complement fixation test has been used in an effort to detect immune complexes in sections of kidney from rats injected with rabbit anti-rat kidney serum and in sections of biopsied kidneys from four humans with membranous glomerulonephritis.
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Effect of tissue fixation on the optical properties of structural components assessed by non-linear microscopy imaging. [PDF]
Biomed Opt Express, 2023 Markus MA +3 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Endoscopic-Assisted Fibula Reduction With Full Percutaneous Fixation of Ankle Fracture Dislocation
Arthroscopy TechniquesAnkle fracture is one of the most commonly encountered fractures. Open reduction and internal fixation is the gold standard of treatment. However, minimally invasive fixation of ankle fracture is gaining popularity among foot and ankle surgeons as the ...
Chau Ming Hong, M.B.Ch.B., F.H.K.C.O.S., F.H.K.A.M. (Orthopaedic Surgery), F.R.C.S.Ed. (Orth.), M.R.C.S.Ed. +1 more
doaj +1 more source
Histological evaluation of PAXgene tissue fixation in Barrett's esophagus and esophageal adenocarcinoma diagnostics. [PDF]
Virchows Arch, 2023 Barroux M +18 more
europepmc +1 more source
Special symposium: fixation and tissue processing models [PDF]
Biotechnic & Histochemistry, 2009 Abstract Fixation and processing of tissue to paraffin blocks permit thin (4-5 microm) sections of tissues to be cut. Tissues and their subcellular components and surrounding stroma are visualized by cutting thin sections and staining them histochemically or immunohistochemically and viewing the sections using a bright field microscope. During the last
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FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source