Results 201 to 210 of about 87,602 (261)

Altered T cell immune profile and its prognostic implications in children with portal hypertension: A pilot study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Immune dysregulation in paediatric portal hypertension (PHT) is poorly understood. We aimed to characterise T cell phenotype and function and circulating immune mediators in children with PHT according to disease aetiology. Methods Forty‐four children with PHT (27 chronic liver disease [CLD]‐related and 17 portal vein thrombosis ...
Tengfei Si, Huihong Yu, Bethany Tucker, Fabiola Di Dato, Qing Shao, Xuan Luo, Cody Chan, Pauline Kane, Dylan Lewis, Eirini Kyrana, Yun Ma, Tassos Grammatikopoulos   +11 more
wiley   +1 more source

Findings Interpretation Concerns Regarding the Emulated Target Trial of SGLT2 Inhibitors vs GLP-1 Receptor Agonists in Psoriatic Arthritis [Letter]. [PDF]

Drug Des Devel Ther
Lymperopoulos A, Leiker MG.
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Late-Onset Preeclampsia Is Linked to Extensive Remodeling of the Placental Extracellular Matrix. [PDF]

Med Sci (Basel)
García-Montero C, Pekarek T, Fraile-Martinez Ó, Boaru DL, de Castro-Martinez P, García-González B, Fanega-Fernández M, Bravo C, De Leon-Luis JA, Diaz-Pedrero R, Lopez-Gonzalez L, Fernandez-Ibañez M, Castilla C, Barrena-Blázquez S, Bujan J, García-Honduvilla N, Alvarez-Mon M, Saez MA, Ortega MA.   +18 more
europepmc   +1 more source

Alterations in MicroRNA and Cytokine Expressions in Placental and Amniotic Tissues of COVID‐19 Affected Pregnant Women

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Since 2019, coronavirus disease 2019 (COVID‐19) has been associated with increased risks of preterm birth and placental complications. We prospectively investigated alterations in microRNAs (miRNAs) and cytokines in placental and amniotic tissues from pregnant women with and without COVID‐19 to evaluate the infection's impact on pregnancy ...
Wei‐Chun Chen, Shu‐Yu Hu, Chao‐Min Cheng, Ching‐Ju Shen   +3 more
wiley   +1 more source

Effects of P38 MAPK Pathway Inhibition on the Metabolism of Periodontal Ligament Fibroblasts During Inflammation. [PDF]

J Cell Mol Med
Qian C, Gu Y, Gao F, Xu Z, Li J, Liu S, He R, Zhong L, Wang J.   +8 more
europepmc   +1 more source

Effect of tipiracil hydrochloride, thymidine phosphorylase inhibitor, on the ischemia/reperfusion injury of brain tissue in rats. [PDF]

Sci Rep
Trocha M, Piasecki T, Nowotarska P, Sozański T, Merwid-Ląd A, Nowak B, Nowak M, Ciaputa R, Mazur G, Szeląg A, Gajecki D, Doroszko A.   +11 more
europepmc   +1 more source

HMGB1 Upregulates MMP-1-Mediated Mesothelial-Mesenchymal Transition and Promotes Pleural Fibrosis in Tuberculous Pleural Effusion. [PDF]

Int J Mol Sci
Chen WL, Lee KL, Chen MC, Hsiao SH, Chung CL.   +4 more
europepmc   +1 more source

Signaling Pathway-Biomarker Coupling for Precision Therapy in Rheumatoid Arthritis: Mechanistic Insights, Translational Bottlenecks, and Emerging Strategies. [PDF]

ACR Open Rheumatol
Meng S, Xing F, Luo Y, Li J, Ni Y, Zhang F, Xu H, Wang Y, Zhang W.   +8 more
europepmc   +1 more source