Results 261 to 270 of about 89,951 (308)

Association of TIMP2 Gene Variants With Development of Diabetic Retinopathy. [PDF]

In Vivo
Huang CT, Chien HW, Wang K, Su SC, Ting CH, Yang SF, Liao MY.   +6 more
europepmc   +1 more source

Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway. [PDF]

Mol Med Rep
Adam MS, Zhuang H, Ren X, Zhang Y, Zhou P.   +4 more
europepmc   +1 more source

<i>Fusobacterium nucleatum</i> promotes colorectal cancer metastasis by modulating the NF-κB-MMP-2/MMP-9 signaling pathway. [PDF]

Transl Cancer Res
Peng C, Liu X, He Q, Hu M, Tie G, Dong Z, Lu C, Shuang J.   +7 more
europepmc   +1 more source

Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium

Fertility and Sterility, 2002
To investigate expression of matrix metalloproteinase-2 (MMP-2), membranous type 1 matrix metalloproteinase (MT1-MMP), and tissue inhibitor of metalloproteinase-2 (TIMP-2) in ectopic and eutopic endometrium from women with and without endometriosis throughout the menstrual cycle.Molecular studies in human tissue.Reproductive immunology laboratory of a ...
Hye Won Chung, Ji Young Lee, Hye-Sung Moon   +2 more
exaly   +4 more sources

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The role of genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes in head and neck cancer

Oral Oncology, 2006
Matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) play an important role in several stages of cancer initiation and development. Single nucleotide polymorphisms identified in the promoters of MMP2 (-1306C-->T) and TIMP2 (-418G-->C) abolish the Sp1-binding site and thus may down-regulate expression of the genes.
Pornchai O-Charoenrat
exaly   +3 more sources

Matrix metalloproteinase‐2 regulates the expression of tissue inhibitor of matrix metalloproteinase‐2

Clinical and Experimental Pharmacology and Physiology, 2010
Summary1. Matrix metalloproteinases (MMP) are associated with the vascular remodelling seen in atherosclerosis and aneurysm. The activation and activity of MMP‐2 are regulated by the intrinsic tissue inhibitor of MMP‐2 (TIMP‐2). The aim of the present study was to examine whether, conversely, MMP‐2 can affect the gene and protein expression of TIMP‐2.2.
Kaoru, Kimura, Xian Wu, Cheng, Kae, Nakamura, Aiko, Inoue, Lina, Hu, Haizhen, Song, Kenji, Okumura, Akihisa, Iguchi, Toyoaki, Murohara, Masafumi, Kuzuya   +9 more
openaire   +2 more sources

Polymorphisms in the matrix metalloproteinase‐2 and tissue inhibitor of metalloproteinase‐2 and the risk of human adenomyosis

Environmental and Molecular Mutagenesis, 2008
AbstractThe matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) may contribute to the development of adenomyosis. The aim of the present study was to investigate whether three single nucleotide polymorphisms (SNPs) in the promoter regions of MMP‐2 (−1306C/T and −735C/T) and TIMP‐2 (‐418G/C) genes were related to the risk
Shan, Kang, Xiwa, Zhao, Huimin, Xing, Na, Wang, Rongmiao, Zhou, Shucheng, Chen, Wansheng, Li, Jian, Zhao, Yanan, Duan, Donglan, Sun, Yan, Li   +10 more
openaire   +2 more sources

Matrix Metalloproteinases 2 and 9 and Their Tissue Inhibitors in the Diagnostics of Medullary Thyroid Carcinoma

Applied Immunohistochemistry & Molecular Morphology, 2022
Medullary Thyroid Carcinoma (MTC) is a tumor of the neuroendocrine system. In recent years, the need to assess the MTC diagnostic-related parameters has emerged with the aim to elucidate the mechanisms involved in this pathology. The objective of this study was to evaluate the role of Matrix Metalloproteinases (MMPs) 2 and 9, their tissue inhibitors of
Héctor Vázquez-Lorente, Duško M. Dunđerović, Svetislav B. Tatić, Sanja Radojević-Škodrić, Cláudio M. Gomes, Ivan R. Paunović, Vesna Dragutinović   +6 more
openaire   +2 more sources