Results 111 to 120 of about 157,447 (201)

Matrix Metalloproteinase-9 and Inflammation in Different Types of Multiple Sclerosis [PDF]

, 2016
Different clinical courses of multiple sclerosis, heterogeneity of its clinical implications, different effect of immunomodulatory therapy for the same clinical forms implies various pathogenetic mechanisms of central nervous system damage at this ...
Chernenko, M. (Maksym), Nehreba, T. (Tatyana), Vasylovskyy, V. (Vitaliy), Voloshyna, N. (Nataliya), Vovk, V. (Viktoriya)   +4 more
core   +2 more sources

Prognostic value of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in bladder carcinoma.

Chinese medical journal, 2002
To detect the level of matrix metalloproteinase-2 (MMP-2) mRNA and the tissue inhibitor of metalloproteinase-2 (TIMP-2) mRNA in bladder transitional cell carcinoma (BTCC), and to estimate the prognosis for bladder tumor based on the quality and quantity of MMP-2 and TIMP-2 mRNA.Thirty-five samples of human BTCC and 15 normal fresh bladder tissues were ...
Kexin, Xu, Shukun, Hou, Zhijun, Du
openaire   +1 more source

Clinical significance of serum levels of matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor (TIMP-2) in gastric cancer

Folia Histochemica et Cytobiologica, 2011
Matrix metalloproteinase 2 (MMP-2) is able to degrade type IV collagen, and thus plays a key role in the migration of tumor cells. MMP-2 activity is inhibited by its tissue inhibitor (TIMP-2).
Maciej Szmitkowski, Bogusław Kędra, Mariusz Gryko, Marta Łukaszewicz-Zając, Barbara Mroczko   +4 more
doaj   +1 more source

JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells

Journal of Biomedical Science, 2011
Background Epidemiological studies demonstrate that the incidence and mortality rates of colorectal cancer in women are lower than in men. However, it is unknown if 17β-estradiol treatment is sufficient to inhibit prostaglandin E2 (PGE2)-induced cellular
Chen Wei-Kung, Chen Li-Mien, Kuo Wei-Wen, Lin Yueh-Min, Hu Wei-Syun, Hsu Hsi-Hsien, Hwang Jin-Ming, Tsai Fuu-Jen, Liu Chung-Jung, Huang Chih-Yang   +9 more
doaj   +1 more source

Perturbed CD81 in lung-cancer-derived extracellular vesicles modifies its function in cancer pathophysiology

Molecular Therapy: Oncology
Lung cancer (LC) remains a leading cause of cancer-related fatalities, necessitating an urgent need for potent treatment strategies. This study investigates the role of extracellular vesicle (EV) cargo: CD81 in lung cancer progression and its potential ...
Anjugam Paramanantham, Siddharth Das, Rahmat Asfiya, Yariswamy Manjunath, Gregory Goetz, Grace McCully, Hu Huang, Jussuf T. Kaifi, Akhil Srivastava   +8 more
doaj   +1 more source

Correlations between papillary thyroid cancer and peripheral blood levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2

Chinese Medical Journal, 2013
Background The relationship between the presence of metalloproteinases and thyroid cancer remains unknown, and many controversies still exist in this field. The objective of this study was to investigate the correlations between papillary thyroid cancer and peripheral blood levels of matrix metalloproteinase-2, matrix ...
Shao-Fei, Zhou, San-Yuan, Hu, Lei, Ma, Lei, Miao, Wei-Zheng, Mao   +4 more
openaire   +2 more sources

Hydroxysafflor Yellow A Suppresses MRC-5 Cell Activation Induced by TGF-β1 by Blocking TGF-β1 Binding to TβRII

Frontiers in Pharmacology, 2017
Hydroxysafflor yellow A (HSYA) is an active ingredient of Carthamus tinctorius L.. This study aimed to evaluate the effects of HSYA on transforming growth factor-β1 (TGF-β1)-induced changes in proliferation, migration, differentiation, and extracellular ...
Ruiyan Pan, Yadan Zhang, Meng Zheng, Baoxia Zang, Ming Jin   +4 more
doaj   +1 more source

[Corrigendum] Human papillomavirus E6‑regulated microRNA‑20b promotes invasion in cervical cancer by targeting tissue inhibitor of metalloproteinase 2. [PDF]

Mol Med Rep, 2023
Cheng Y, Geng L, Zhao L, Zuo P, Wang J.
europepmc   +1 more source

Expression of MMP-13 in Human Temporomandibular Joint Disc Derangement and Osteoarthritis [PDF]

, 2017
Objective: MMP-13 performs digestion of collagen, which is a primary component of the temporomandibular joint (TMJ) articular disc. This study evaluated the expression of MMP-13 in patients with anterior disc displacement with (ADDwR) and without ...
Almeida, Luis Eduardo, Azevedo, Marina, Camejo, Flavio, Doetzer, Andrea, Olandoski, Marcia, Perotto, Juliano Henrique   +5 more
core   +1 more source

A Clinicoimmunohistopathologic Study of Anetoderma: Is Protruding Type More Advanced in Stage Than Indented Type?

Journal of Immunology Research, 2016
Background. The clinical and histopathologic classification of anetoderma are not well characterized. Objective. We aimed to investigate the clinical and histopathologic characteristics of anetoderma and to correlate clinical phenotypes with ...
Jung Eun Kim, Ki Min Sohn, Young Jun Woo, Kwan Ho Jeong, Miri Kim, Jeong Deuk Lee, Jun Young Lee, Hyun Jeong Park, Gyong Moon Kim, Chul Jong Park, Dong Soo Yu, Hoon Kang   +11 more
doaj   +1 more source