Results 131 to 140 of about 174,221,971 (253)

Maternal Plasma Levels of MMP-2, MMP-3, MMP-9, TIMP-1, and TIMP-2 as Predictive Biomarkers of Preeclampsia

Clinical and Experimental Obstetrics & Gynecology
Background: Preeclampsia (PE), a severe pregnancy complication, is a major contributor to maternal and perinatal morbidity and mortality worldwide.
Thuy Thanh Nguyen, Ngoc Anh Le, Do Tung Dac, Thi Ngoc Dung Ngo, Son Hai Doan, Thi Ngoc Thao Nguyen   +5 more
doaj   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Evaluation of Effect of Propranolol on Serum Vascular Endothelial Growth Factor and Tissue Inhibitor of Metalloproteinase-2 Levels in Infantile Hemangioma. [PDF]

J Indian Assoc Pediatr Surg, 2020
Pandey A, Singh A, Ali W, Srivastava A, Gupta A, Kureel SN, Rawat J, Wakhlu A.   +7 more
europepmc   +1 more source

Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

Advanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen, Danni Yang, Songying Pi, Yuhan Liu, Hongbin Huang, Feile Ye, Yuhong Lin, Zhongzhen Su, Yongquan Huang   +8 more
wiley   +1 more source

Inhibitor regulation of tissue kallikrein activity in the synovial fluid of patients with rheumatoid athritis [PDF]

, 1994
Tissue kallikrein (TK) and 1-antitrypsin (AT)/TK complexes can be detected in SF from patients with RA if components of the fluids which interfere with the detection of TK are removed.
Bhoola, K. D., Elson, C. J., Dieppe, P. A., Worthy, K., Rahman, M. M., Fink, Edwin   +5 more
core  

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

Advanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu   +8 more
wiley   +1 more source

Identification of novel molecular scaffolds for the design of MMP-13 inhibitors through Virtual Screening Methods [PDF]

, 2010
Osteoarthritis (OA) is the leading cause of joint pain and disability in middle-aged and elderly patients. It is characterized by progressive loss of articular cartilage that eventually leads to denudation of the joint surface.
La Pietra, Valeria
core  

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

The Role Of Green Tea Against Polifenol Matrix Metalloproteinase-2 (MMP2), Tissue Inhibitor Matrix Metalloproteinase-1 (TIMP-1) In Early childhood Caries.

, 2016
-The Role Of Green Tea Against Polifenol Matrix Metalloproteinase-2 (MMP2), Tissue Inhibitor Matrix Metalloproteinase-1 (TIMP-1) In Early childhood ...
Baru Fajriani, Baru Fajriani
core   +1 more source

Urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor-binding protein 7 as biomarkers of patients with established acute kidney injury. [PDF]

Korean J Intern Med, 2020
Cho WY, Lim SY, Yang JH, Oh SW, Kim MG, Jo SK.   +5 more
europepmc   +1 more source