Results 1 to 10 of about 98,121 (165)

Relationship between Circulating Serpina3g, Matrix Metalloproteinase-9, and Tissue Inhibitor of Metalloproteinase-1 and -2 with Chronic Obstructive Pulmonary Disease Severity

open access: yesBiomolecules, 2019
Chronic obstructive pulmonary disease (COPD) is influenced by genetic and environmental factors. A protease-antiprotease imbalance has been suggested as a possible pathogenic mechanism for COPD.
Pelin Uysal, Hafize Uzun
doaj   +3 more sources

Secretory autophagy promotes Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 [PDF]

open access: yesJournal of Biomedical Science, 2022
Background Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 (TIMP1), an inflammatory cytokine, under serum-depleted conditions which leads to suppression of lung cancer cell metastasis has been reported.
Shan-Ying Wu   +8 more
doaj   +2 more sources

Tissue Inhibitor of Metalloproteinase-3 Ameliorates Diabetes-Induced Retinal Inflammation [PDF]

open access: yesFrontiers in Physiology, 2022
Purpose: Endogenous tissue inhibitor of matrix metalloproteinase-3 (TIMP-3) has powerful regulatory effects on inflammation and angiogenesis. In this study, we investigated the role of TIMP-3 in regulating inflammation in the diabetic retina.Methods ...
Ahmed M. Abu El-Asrar   +10 more
doaj   +2 more sources

Investigation of the relationship between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase with SARS CoV-2 infections

open access: yesJournal of Advanced Biotechnology and Experimental Therapeutics, 2023
SARS-CoV-2 stands for severe acute respiratory syndrome coronavirus 2 which is the causative agent of spreading coronavirus disease 2019 that is known as COVID-19 pandemic, the disease leads to severe acute respiratory illness. Matrix metalloproteinases-
May K. Ismael   +2 more
doaj   +1 more source

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases [PDF]

open access: yesCirculation Research, 2003
Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the extracellular matrix. These proteinases play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis, and in diseases such as atheroma, arthritis, cancer, and tissue ulceration.
Visse, R, Nagase, H
openaire   +2 more sources

The intestinal sutures insufficiency: factors of risk and prognostication, based on genetic investigations

open access: yesКлінічна хірургія, 2022
Objective. To improve the results of treatment in patients, suffering insufficiency of sutures of intestinal anastomoses, using analysis of rate in the genes polymorphous variants of the matrix metalloproteinase Type 2 (C-1306 →T) and the tissue ...
O. Yu. Usenko, Ya. Yu. Voitiv
doaj   +1 more source

Metalloproteinases and tissue inhibitors of metalloproteinases in exudative pleural effusions [PDF]

open access: yesEuropean Respiratory Journal, 2005
The aim of this study was to assess the expression of several metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in exudative pleural effusions, and their relationship with inflammatory and fibrinolytic mediators in parapneumonic effusions.The study included 51 parapneumonic effusions (30 empyema or complicated parapneumonic,
D, Iglesias   +9 more
openaire   +2 more sources

Salivary molecules of bone remodeling and tissue repair after head and neck radiotherapy

open access: yesBrazilian Oral Research, 2021
Head and neck radiotherapy causes quantitative and qualitative changes in saliva. The objective of this case-control study was to evaluate the salivary biomarkers associated with bone remodeling and tissue repair in patients submitted to radiotherapy for
Eduardo Morato de OLIVEIRA   +6 more
doaj   +1 more source

Tissue inhibitors of metalloproteinases [PDF]

open access: yesGenome Biology, 2011
Orchestration of the growth and remodeling of tissues and responses of cells to their extracellular environment is mediated by metalloproteinases of the Metzincin clan. This group of proteins comprises several families of endopeptidases in which a zinc atom is liganded at the catalytic site to three histidine residues and an invariant methionine ...
openaire   +2 more sources

Matrix metalloproteinases and their tissue inhibitors as novel markers in invasive pituitary adenomas – a review

open access: yesJournal of Education, Health and Sport, 2019
Introduction: Pituitary adenomas are generally benign central nervous system neoplasms with still increasing prevalence, especially in younger people.
Joanna Szydełko   +2 more
doaj   +3 more sources

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