Results 31 to 40 of about 158,026 (312)

Clinical Investigation of Matrix Metalloproteinases, Tissue Inhibitors of Matrix Metalloproteinases, and Matrix Metalloproteinase/Tissue Inhibitors of Matrix Metalloproteinase Complexes and Their Networks in Apical Periodontitis [PDF]

Journal of Endodontics, 2016
This clinical study investigated the levels of metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) and respective forms (MMP/TIMP complexes) in apical periodontitis to determine their networks in the development of clinical/radiographic features, thus quantifying the levels of endotoxins (lipopolysaccharides) present in primarily infected ...
Frederico C. Martinho, Flávia F.C. Teixeira, Flávia G.R. Cardoso, Nádia S. Ferreira, Gustavo G. Nascimento, Cláudio A.T. Carvalho, Márcia C. Valera   +6 more
openaire   +3 more sources

CCAAT/enhancer binding protein β expression is increased in the brain during HIV-1-infection and contributes to regulation of astrocyte tissue inhibitor of metalloproteinase-1 [PDF]

, 2011
Human immunodeficiency virus (HIV)-1-associated neurocognitive disorders (HAND) associated with infection and activation of mononuclear phagocytes (MP) in the brain, occur late in disease. Infected/activated MP initiate neuroinflammation activating glial
Abraham, Akira, Alberini, Albertini, Borjabad, Brambilla, Brambilla, Bugno, Cardinaux, Chaillan, Chen, Clark, Cortes-Canteli, Crocker, Dean, Dean, Dhar, Ejarque-Ortiz, Fassina, Faulkner, Ferrari, Ferrari, Gardner, Gardner, Gris, Heales, Herrmann, Hornebeck, Jaworski, Jourquin, La Fleur, Laird, Lindl, Liu, Lorenzl, Lorenzl, Lorenzl, Manthrope, Menard, Nadeau, Oberheim, Ould-yahoui, Pagenstecher, Panenka, Phillips, Rivera, Sandhir, Sears, Sofroniew, Sofroniew, Sterneck, Suryadevara, Yadav, Yong, Yukawa   +54 more
core   +1 more source

Pleiotropic functions of the tumor- and metastasis-suppressing Matrix Metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice [PDF]

, 2015
Matrix metalloproteinase-8 (MMP-8; neutrophil collagenase) is an important regulator of innate immunity which has onco-suppressive actions in numerous tumor ...
A Dufour, A Gutierrez-Fernandez, A Gutiérrez-Fernández, A Krüger, AM Tester, Ana Gutiérrez-Fernández, B Fingleton, B Fingleton, C López-Otín, C Soria-Valles, CM Overall, CT Guy, D Agarwal, Dylan R Edwards, E Dejonckheere, EI Deryugina, EM Bekes, EY Lin, EY Lin, G Christoffersson, G Dew, H Nozawa, J Decock, J Decock, J Decock, J Decock, J Schindelin, J Wyckoff, JE Maglione, JP Väyrynen, JP Witty, JT Korpi, JT Korpi, Julie Decock, K Almholt, L Sevenich, LH Palavalli, LJ McCawley, M Balbin, M Egeblad, M Hernández, M Lin, M Zhu, MM Gueders, N Fortelny, N Xu, P Li, P Lint Van, S Tazzyman, S Thirkettle, Sally Thirkettle, Stephen D Robinson, T Pellinen, T-Y Wu, V Knäuper, V Montel, W Wang, Wouter Hendrickx, Y Lang, Y-H Lin, Z Yang, Z-G Zhao, ZG Fridlender   +62 more
core   +3 more sources

Influence of diuretics with antialdosterone effect on the condition of extracellular matrix and early postinfarction remodeling of the left ventricle in patients with Q-wave myocardial infarction

Zaporožskij Medicinskij Žurnal, 2015
Objective. Aldosterone receptor blockade regulate activity of matrix metalloproteinase system, increase survival in postinfarction period. Methods and results.
S. M. Kyselov
doaj   +1 more source

Matrix metalloproteinases-9 and tissue inhibitor of matrix metalloproteinases-1 in sarcoidosis patients [PDF]

Arhiv za farmaciju, 2017
Matrix metaloproteinases (MMPs) and their specific inhibitors - tissue inhibitors of matrix metalloproteinases (TIMPs) play an important role in pulmonary extracellular matrix destruction. Sarcoidosis is an inflammatory disease affecting multiple organs.
Ivanišević Jasmina, Stefanović Aleksandra, Kotur-Stevuljević Jelena, Jelić-Ivanović Zorana, Spasić Slavica, Videnović-Ivanov Jelica, Mihailović-Vučinić Violeta   +6 more
doaj   +1 more source

Kinetics of urinary cell cycle arrest markers for acute kidney injury following exposure to potential renal insults [PDF]

, 2018
Objectives: Urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor binding protein 7 predict the development of acute kidney injury following renal insults of varied aetiology.
Aliaga, Bellomo, Bihorac, Bonventre, Charlton, Emlet, Goldstein, Gunnerson, Honore, Hoste, Hoste, Jia, Joannidis, Kane-Gill, Kashani, Kaufman, Kerr, Lewington, McDonald, Meersch, Mehta, Mehta, Murrary, Peng, Perazella, Uchino, Waring, Wu   +27 more
core   +1 more source

TL1A/DR3 axis involvement in the inflammatory cytokine network during pulmonary sarcoidosis [PDF]

, 2015
BACKGROUND: TNF-like ligand 1A (TL1A), a recently recognized member of the TNF superfamily, and its death domain receptor 3 (DR3), firstly identified for their relevant role in T lymphocyte homeostasis, are now well-known mediators of several immune ...
A. Cabrelle, A. Teramo, C Agostini, C Agostini, C Agostini, C Agostini, C Agostini, C Agostini, C. Agostini, F Meylan, F. Calabrese, F. Calzetti, F. Cinetto, G Bamias, G Bamias, G Bamias, G Mautino, G. Semenzato, GW Jones, J Müller-Quernheim, KA Oswald-Richter, KL Wallace, KS Lee, L Li, L Nissinen, M Facco, M Facco, M. A. Cassatella, M. Facco, MA Cassatella, MA Judson, MT Henry, N Kamada, N Kamada, N. Tamassia, R Polverosi, RE Vandenbroucke, S. Carraro, SK Bedoya, TH Schreiber, TS Migone, V. Martini, VY Taraban, X Sun, Y Aiba, YJ Kang   +45 more
core   +1 more source

IL-1β-Induced Matrix Metalloprotease-1 Promotes Mesenchymal Stem Cell Migration via PAR1 and G-Protein-Coupled Signaling Pathway

Stem Cells International, 2018
Mesenchymal stem cells (MSCs) are known for homing to sites of injury in response to signals of cellular damage. However, the mechanisms of how cytokines recruit stem cells to target tissue are still unclear.
Ming-Siou Chen, Cheng-Yu Lin, Yun-Hsuan Chiu, Chie-Pein Chen, Pei-Jiun Tsai, Hwai-Shi Wang   +5 more
doaj   +1 more source

Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]

, 2018
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila, Chernov, Andrei V, Dolkas, Jennifer, Hullugundi, Swathi K, Remacle, Albert G, Shubayev, Veronica I, Strongin, Alex Y   +6 more
core   +2 more sources

Designing TIMP (tissue inhibitor of metalloproteinases) variants that are selective metalloproteinase inhibitors

Biochemical Society Symposia, 2003
The tissue inhibitors of metalloproteinases (TIMPs) are endogenous inhibitors of the matrix metalloproteinases (MMPs), enzymes that play central roles in the degradation of extracellular matrix components. The balance between MMPs and TIMPs is important in the maintenance of tissues, and its disruption affects tissue homoeostasis.
Nagase, H, Brew, K
openaire   +3 more sources