Results 141 to 150 of about 122,684 (358)

Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging. [PDF]

eNeuro, 2023
Britton R, Wasley T, Harish R, Holz C, Hall J, Yee DC, Melton Witt J, Booth EA, Braithwaite S, Czirr E, Kerrisk Campbell M.   +10 more
europepmc   +1 more source

Regulation and Localization of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in the Mouse Ovary during Gonadotropin-Induced Ovulation [PDF]

, 1999
Anna-Carin Hägglund
openalex   +1 more source

The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice [PDF]

, 2007
Dissemination of metastatic cells probably occurs long before diagnosis of the primary tumor. Metastasis during early phases of carcinogenesis in high risk patients is therefore a potential prevention target.
Adriana Albini, Aggarwal BB, Aggarwal S, Airola K, Albini A, Albini A, Ammon HP, Andreas Nerlich, Bachmeier BE, Bachmeier BE, Bachmeier BE, Bachmeier BE, Bachmeier BE, Bachmeier BE, Bachmeier BE, Balduyck M, Banerji A, Beatrice Bachmeier, Benbow U, Benbow U, Bharti AC, Biswas DK, Cailleau R, Cailleau R, Chen H, Chen Z, Commandeur JN, Cristina Iancu, Divya CS, Erwin Schleicher, Garg A, Hahm ER, Hong JH, Hozumi A, Huang MT, Hunter KW, Ichiki K, Kawamori T, Kossakowska AE, Kuo ML, Li L, Limtrakul P, Manna SK, Marianne Jochum, Meade-Tollin LC, Mehta K, Menon LG, Menon LG, Michele Cilli, Mukaida N, Nagabhushan M, Nakshatri H, Netzker R, Noel A, Ohashi Y, Park AM, Park CH, Philip S, Raffaella Dell'Eva, Roberta Vené, Shao ZM, Stetler-Stevenson WG, Tetu B, Ulrich Pfeffer, Vincenti MP, Vincenti MP, Vincenti MP, Westermarck J, Wu JT, Yu G, Zhang RD   +70 more
core   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Metalloproteinases in Inflammatory Bowel Diseases

Journal of Inflammation Research, 2021
Martin Marônek,1,* Irene Marafini,2,* Roman Gardlík,1 René Link,3 Edoardo Troncone,2 Giovanni Monteleone2 1Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University in Bratislava, Bratislava, 81108, Slovakia ...
Marônek M, Marafini I, Gardlík R, Link R, Troncone E, Monteleone G   +5 more
doaj  

Impact of tissue inhibitor of metalloproteinases-3 genetic variants on clinicopathological characteristics of urothelial cell carcinoma. [PDF]

J Cancer, 2023
Weng WC, Hsieh MH, Chiou HL, Lee CY, Tang CH, Chang LC, Wang SS, Yang SF.   +7 more
europepmc   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

The role of tissue inhibitor of metalloproteinases in the aetiology of inguinal and incisional hernias. [PDF]

Int Wound J, 2022
Durukan U, Agcaoglu O, Ozoran E, Karahan SN, Ozata I, Duzkoylu Y, Pasaoglu E, Aren A.   +7 more
europepmc   +1 more source

Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros [PDF]

, 1999
Jonathan Barasch, Jun Yang, Jizeng Qiao, Paul Tempst, Hediye Erdjument‐Bromage, Winnie Leung, Juan Oliver   +6 more
openalex   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source