Patients with coronavirus disease-19 (COVID-19) are at high risk for thrombotic arterial and venous occlusions. However, bleeding complications have also been observed in some patients.
Yu Zuo +9 more
doaj +2 more sources
Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines [PDF]
Background Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants.
Paola Pontecorvi +8 more
doaj +3 more sources
Diagnostic Ultrasound Induced Inertial Cavitation To Non-Invasively Restore Coronary And Microvascular Flow In Acute Myocardial Infarction [PDF]
Ultrasound induced cavitation has been explored as a method of dissolving intravascular and microvascular thrombi in acute myocardial infarction. The purpose of this study was to determine the type of cavitation required for success, and whether longer ...
Everbach, E. Carr +11 more
core +28 more sources
Hyperperfusion Syndrome Following Tissue Plasminogen Activator Administration: A Case Report with Radiological Evidence [PDF]
Cerebral hyperperfusion syndrome is a rare complication that can occur following carotid artery revascularization procedures in patients with chronic carotid artery stenosis.
Nam Hee Koh +4 more
doaj +2 more sources
Incidence of Hemorrhagic Complications among Patients Treated with Thrombolytic in Erbil City, Iraq [PDF]
Background: Recombinant tissue-type plasminogen activator is an option of treatment for suspected occlusive vascular thrombi and its sequel (transmural myocardial infarction, pulmonary embolism, and ischemic stroke). The most important concern associated
Ahmed F. Hammad +2 more
doaj +1 more source
Histone deacetylase inhibitor treatment increases coronary t-PA release in a porcine ischemia model. [PDF]
BACKGROUND: The expression of the tissue plasminogen activator gene can be affected by histone deacetylation inhibition and thus appears to be under epigenetic control.
Kristina Svennerholm +6 more
doaj +1 more source
A prothrombotic coagulopathy is commonly found in critically ill COVID‐19 patients with acute respiratory distress syndrome (ARDS). A unique feature of COVID‐19 respiratory failure is a relatively preserved lung compliance and high Alveolar‐arterial ...
Janice Wang +8 more
semanticscholar +1 more source
Background: Patients with coronavirus disease 19 (COVID-19) are at high risk for thrombotic arterial and venous occlusions, while lung histopathology often reveals fibrin-based occlusion of small vessels in patients who succumb to the disease.
Y. Zuo +9 more
semanticscholar +1 more source
Peripheral embolization following thrombolytic therapy for acute ischemic stroke—a case report
Background Intravenous recombinant tissue plasminogen activator is the only golden approved medical therapy for acute ischemic stroke, guidelines for its injection relay on reducing or preventing associated hemorrhage as a side effect, yet hemorrhage is ...
Tamer Roushdy +5 more
doaj +1 more source
Intravenous tissue plasminogen activator in functional stroke mimics [PDF]
Magdalena M. Kowalska +2 more
doaj +2 more sources

