Results 251 to 260 of about 83,548 (314)

Alleviating Recombinant Tissue Plasminogen Activator-induced Hemorrhagic Transformation in Ischemic Stroke via Targeted Delivery of a Ferroptosis Inhibitor. [PDF]

Adv Sci (Weinh)
Geng YQ, Qiu LN, Cheng YQ, Li JJ, Ma YL, Zhao CC, Cai Y, Zhang XB, Chen J, Pan YC, Wang KR, Yao XH, Guo DS, Wu JL.   +13 more
europepmc   +1 more source

Differences in Acute Expression of Matrix Metalloproteinases-9, 3, and 2 Related to the Duration of Brain Ischemia and Tissue Plasminogen Activator Treatment in Experimental Stroke. [PDF]

Int J Mol Sci
Wang D, Saleem S, Sullivan RD, Zhao T, Reed GL.   +4 more
europepmc   +1 more source

Catheter-Directed Arterial Thrombolysis with a Low-Dose Recombinant Tissue Plasminogen Activator Regimen for Acute Lower Limb Ischemia-Results of the First Regional Registry of Acute Limb Ischemia in Romania. [PDF]

Life (Basel)
Barac S, Onofrei RR, Barbu O, Pantea S, Pleșoianu C, Gîndac C, Timar B, Rață AL.   +7 more
europepmc   +1 more source

The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity. [PDF]

Diabetologia
Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE.   +13 more
europepmc   +1 more source

Is Intravitreal Injection of Recombinant Tissue Plasminogen Activator Effective for the Treatment of Refractory Diabetic Macular Edema in Patients With Posterior Vitreous Detachment? [PDF]

Cureus
Berk Ergun Ş, Toklu Y, Arıkan Yorgun M, Mutlu Sönmez M, Arifoğlu HB, Çakmak HB.   +5 more
europepmc   +1 more source

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Tissue Activator of Plasminogen

Nature, 1964
SINCE Astrup and Permin1 reported that animal tissue cells contain an activator of plasminogen, various authors have confirmed their results, and comparisons of the activator content of different human2 and animal tissues3,4 have been published. Most authors have used whole tissue or aqueous tissue extracts and have estimated activity by the fibrin ...
Charles H. Lack, S. Yousuf Ali
openaire   +3 more sources

Tissue Plasminogen Activator

New England Journal of Medicine, 1988
TISSUE plasminogen activator (t-PA) is a naturally occurring protein that catalyzes the conversion of the inactive proenzyme plasminogen into the active serine protease plasmin.
John A. Oates, Alastair J.J. Wood, Joseph Loscalzo, Eugene Braunwald   +3 more
openaire   +3 more sources

Plasminogen activation by tissue plasminogen activator in the presence of platelets

Thrombosis Research, 1988
Platelets were found to provide a surface for activation of plasminogen by the tissue-type plasminogen activator (t-PA) at an optimum concentration and to potentiate the generation of plasmin by the amidolytic method, fibrin lysis time and fibrin plate method.
Katsumi Deguchi, Shigeru Shirakawa
openaire   +3 more sources

Activation of Bovine Plasminogen by the Plasminogen Activator in Animal Tissue

Thrombosis and Haemostasis, 1960
Summary1. The activation of bovine plasminogen by means of the plasminogen activator from pig heart tissue has been studied on heated fibrin and on casein.2. Small, but varying, amounts of activator can be extracted from crude activator powder during the experiment and interfere therefore with estimations on normal, plasminogen containing fibrin.3. The
Takeshi Abe, Tage Astrup
openaire   +3 more sources