Results 41 to 50 of about 4,698,204 (249)
Journal of Nanobiotechnology, 2021 Background The regeneration of periodontal bone defect remains a vital clinical challenge. To date, numerous biomaterials have been applied in this field. However, the immune response and vascularity in defect areas may be key factors that are overlooked
Tian Ding +4 more
doaj +1 more source
Advanced Functional Materials, 2020 The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to their secreted factors, including extracellular vesicles (EVs) and soluble factors.
Meadhbh Á. Brennan +2 more
semanticscholar +1 more source
Fabrication of Scaffolds for Bone-Tissue Regeneration
Materials, 2019 The present article describes the state of the art in the rapidly developing field of bone tissue engineering, where many disciplines, such as material science, mechanical engineering, clinical medicine and genetics, are interconnected.
Petra Chocholata, V. Kulda, V. Babuška
semanticscholar +1 more source
MicroRNAs Regulating Hippo-YAP Signaling in Liver Cancer
Biomedicines, 2021 Liver cancer is one of the most common cancers worldwide, and its prevalence and mortality rate are increasing due to the lack of biomarkers and effective treatments.
Na-Hyun Lee, So Jung Kim, Jeongeun Hyun
doaj +1 more source
Stem Cell Research & Therapy, 2020 Background Periodontal ligament stem cells (PDLSCs) have many applications in the field of cytotherapy, tissue engineering, and regenerative medicine.
Xiaoyu Li +6 more
doaj +1 more source
The Chemokine Receptor CXCR4 in Cell Proliferation and Tissue Regeneration
Frontiers in Immunology, 2020 The CXCR4 receptor upon binding its ligands triggers multiple signaling pathways that orchestrate cell migration, hematopoiesis and cell homing, and retention in the bone marrow.
M. Bianchi, R. Mezzapelle
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Advanced therapeutic scaffolds of biomimetic periosteum for functional bone regeneration
Journal of NanobiotechnologyTreating chronic bone injuries and defects remains a significant challenge in orthopedic medicine, impacting patient mobility, recovery time, and healthcare costs.
Archita Gupta +6 more
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FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
A high-glucose diet affects Achilles tendon healing in rats
Scientific Reports, 2017 Chronic and acute tendinopathies are difficult to treat and tendon healing is generally a very slow and incomplete process and our general understanding of tendon biology and regeneration lags behind that of muscle or bone.
Stefanie Korntner +10 more
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