Results 91 to 100 of about 17,677,818 (279)

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Metabolic Reprogramming and Longevity of Tissue-Resident Memory T Cells

Frontiers in Immunology, 2018
Tissue-resident memory T cells (TRM) persist in peripheral tissues for long periods of time in the absence of antigenic stimulation. Upon re-encounter with cognate antigen, TRM trigger an immediate immune response at the local tissue microenvironment and
Youdong Pan, Thomas S. Kupper
doaj   +1 more source

Tissue-resident memory T cells and their function in skin diseases. [PDF]

Chin Med J (Engl)
Abstract Tissue-resident memory T (TRM) cells are a recently defined subtype of non-recirculating memory T cells with longevity and protective functions in peripheral tissues. As an essential frontline defense against infections, TRM cells have been reported to robustly patrol the tissue microenvironment in malignancies ...
Chen X, Zheng Y, Man X, Li W.
europepmc   +4 more sources

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Spatial organization of tissue-resident memory T cells

Immunity
Tissue-resident memory T (TRM) cells durably reside in peripheral tissues, poised to deliver rapid local immune protection. TRM cells are found in most organs, and they are a core component of immunological memory, complementing circulating memory T cell populations.
Thomas N, Burn, Laura K, Mackay
openaire   +2 more sources

Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function

Frontiers in Immunology, 2018
Tissue-resident memory CD8+ T cells are an important first line of defense from infection in peripheral non-lymphoid tissues, such as the mucosal tissues of the respiratory, digestive, and urogenital tracts.
David J. Topham, David J. Topham, Emma C. Reilly   +2 more
doaj   +1 more source

Dataset for The role of airway tissue-resident memory T cells in severe asthma

Dataset containing all data generated and used for the PhD thesis 'The Role of Airway Tissue-Resident Memory T Cells in Severe Asthma' and the published journal article titled 'Cytotoxic CD4+ tissue-resident memory T cells are associated with
Vijayanand, Pandurangan, Herrera-de La Mata, Sara, Mistry, Heena, Ramirez suastegui, Ciro, Arshad, Hasan, Kurukulaaratchy, Ramesh, Seumois, Grégory   +6 more
core   +1 more source

Tissue-resident CD4+ T helper cells assist the development of protective respiratory B and CD8+ T cell memory responses

, 2021
Much remains unknown about the roles of CD4+ T helper cells in shaping localized memory B cell and CD8+ T cell immunity in the mucosal tissues. Here, we report that lung T helper cells provide local assistance for the optimal development of tissue ...
Son, Young Min, Wang, Zheng, Taylor, Justin J., Chen, Yao, Sun, Jie, Takahashi, Yoshimasa, Kaplan, Mark H., Gao, Xiaochen, Fu, Yang-Xin, Wu, Yue, Cheon, In Su, Li, Chaofan, Dent, Alexander L., Cui, Weiguo, Xiaochen Gao, Weiguo Cui, Mark H. Kaplan, Alexander L. Dent, Zheng Wang, Yoshimasa Takahashi, Yue Wu, Jie Sun, Yang-Xin Fu, In Su Cheon, Yao Chen, Young Min Son, Chaofan Li, Justin J. Taylor   +27 more
core   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

Advanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han, Shuvra Mondal, Sungkeun Han, Chan‐Hwi Eom, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +5 more
wiley   +1 more source

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

Advanced Functional Materials, EarlyView.
The physical realization of artificial neurons is a critical challenge for energy‐efficient neuromorphic computing. This review presents a comprehensive analysis of the evolution of artificial neuron implementations from conventional CMOS to emerging post‐CMOS technologies.
Kannan Udaya Mohanan, Hocheon Yoo, Benoît H. Lessard, Ioannis Kymissis, Chang‐Hyun Kim   +4 more
wiley   +1 more source