Results 31 to 40 of about 1,869 (165)

Scorpion venom increases acetylcholine release by prolonging the duration of somatic nerve action potentials [PDF]

, 2019
Scorpionism is frequently accompanied by a massive release of catecholamines and acetylcholine from peripheral nerves caused by neurotoxic peptides present in these venoms, which have high specificity and affinity for ion channels.
Antunes, Edson, Collaço, Rita de Cássia O., Dorce, Valquíria A.C., Hyslop, Stephen, Rowan, Edward G.   +4 more
core   +2 more sources

Model for Vaccine Design by Prediction of B‐Epitopes of IEDB Given Perturbations in Peptide Sequence, In Vivo Process, Experimental Techniques, and Source or Host Organisms

Journal of Immunology Research, Volume 2014, Issue 1, 2014., 2014
Perturbation methods add variation terms to a known experimental solution of one problem to approach a solution for a related problem without known exact solution. One problem of this type in immunology is the prediction of the possible action of epitope of one peptide after a perturbation or variation in the structure of a known peptide and/or other ...
Humberto González-Díaz, Lázaro G. Pérez-Montoto, Florencio M. Ubeira, Darren R. Flower   +3 more
wiley   +1 more source

Convulsive and Neurodegenerative Effects in Rats of Some Isolated Toxins from the Tityus bahiensis Scorpion Venom

Journal of Toxins, Volume 2013, Issue 1, 2013., 2013
Despite Tityus bahiensis being one of the most dangerous scorpions in Brazil, there are few studies about the effects of its venom, which acts mainly on the central nervous system. Previous studies demonstrated the convulsive ability of this venom.
Luciene Toshie Takeishi Ossanai, Geane Antiques Lourenço, Ivo Lebrun, Ana Leonor Abrahão Nencioni, Valquiria Abrão Coronado Dorce, Andreimar Martins Soares   +5 more
wiley   +1 more source

Tityus serrulatus Lutz & Mello 1922

, 2009
Tityus serrulatus Lutz & Mello, 1922 Tityus serrulatus serrulatus Lutz & Mello, 1922: 25. Holotype Ψ from Belo Horizonte, Minas Gerais, Brazil (lost). Neotype Ψ from Belo Horizonte, Minas Gerais, Brazil (IBSP–1165) (designated by Lourenço & Eickstedt, 1981); Lourenço & Cloudsley-Thompson, 1999: 154 –158; Fet et al, 2000: 260–261; Lourenço, 2001: 21 –25,
De, Claudio Augusto R., Candido, Denise M., Lucas, Sylvia Marlene, Brescovit, Antonio Domingos   +3 more
openaire   +1 more source

Scorpion Peptides: Potential Use for New Drug Development

Journal of Toxicology, Volume 2013, Issue 1, 2013., 2013
Several peptides contained in scorpion fluids showed diverse array of biological activities with high specificities to their targeted sites. Many investigations outlined their potent effects against microbes and showed their potential to modulate various biological mechanisms that are involved in immune, nervous, cardiovascular, and neoplastic diseases.
BenNasr Hmed, Hammami Turky Serria, Zeghal Khaled Mounir, Robert Tanguay   +3 more
wiley   +1 more source

Genomic organization of the KTX2 gene, encoding a `short' scorpion toxin active on K+ channels [PDF]

, 1997
A single intron of 87 bp, close to the region encoding the C-terminal part of the signal peptide, was found in the gene of the `short' scorpion toxin kaliotoxin 2 of Androctonus australis acting on various types of K+ channels.
Legros, Christian, Bougis, Pierre E, Martin-Eauclaire, Marie-France   +2 more
core   +1 more source

Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View

Journal of Toxicology, Volume 2012, Issue 1, 2012., 2012
Nervous system of Periplaneta americana cockroach is used in a wide range of pharmacological studies, including electrophysiological techniques. This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double‐oil‐gap technique on isolated giant axon, patch‐clamp on DUM ...
Maria Stankiewicz, Marcin Dąbrowski, Maria Elena de Lima, Yonghua Ji   +3 more
wiley   +1 more source

Scorpionism in Brazil in the years 2000 to 2012 [PDF]

, 2014
Background: Scorpionism is a serious public health problem in Brazil. Nationwide epidemiological analyses of scorpion stings are scarce. In this context, the present study aims to provide an epidemiological analysis of accidents involving scorpions in ...
Pinto Júnior, Vitor Laerte, Reckziegel, Guilherme Carneiro   +1 more
core   +5 more sources

Identification of an Antimicrobial Peptide from the Venom of the Trinidad Thick-Tailed Scorpion Tityus trinitatis with Potent Activity against ESKAPE Pathogens and Clostridioides difficile [PDF]

, 2023
Envenomation by the Trinidad thick-tailed scorpion Tityus trinitatis may result in fatal myocarditis and there is a high incidence of acute pancreatitis among survivors. Peptidomic analysis (reversed-phase HPLC followed by MALDI-TOF mass spectrometry and
Calvete, Juan, Conlon, JM, Coquet, Laurent, Cunning, Taylor, Jouenne, Thierry, Leprince, Jérôme, Mechkarska, Milena, Taggart, Megan, Tena-Garcés, Jordi, Ternan, Nigel G   +9 more
core   +1 more source

Immunomodulatory Effects of the Tityus serrulatus Venom on Murine Macrophage Functions in Vitro

Mediators of Inflammation, Volume 2005, Issue 1, Page 39-49, 2005., 2005
Tityus serrulatus scorpion venom (TSV) consists of a very complex mixture of molecules and demonstrates significant immunomodulatory activities capable of stimulating immune functions in vivo. The purpose of this study was to compare the crude TSV with fractionated toxins extracted from this venom in order to determine which toxin(s) presented ...
Vera L. Petricevich, Ivo Lebrun
wiley   +1 more source