Results 281 to 290 of about 156,491 (330)

Deciphering the clinical implication of an obesity-related gene signature as the novel biomarker for acute myocardial infarction diagnosis. [PDF]

Sci Rep
Dong W, Xue Z, Zhang M, Lu F, Ji S.
europepmc   +1 more source

Altered Inflammatory Signature in a C9ORF72 ‐ALS iPSC‐Derived Motor Neuron and Microglia Coculture Model

Glia, Volume 74, Issue 1, January 2026.
Established a C9ORF72 ALS microglia and motor neuron coculture model. Identified an altered inflammatory signature in C9ORF72 ALS microglia. Single‐cell RNA sequencing detected the removal of an LPS responsive microglia subpopulation. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder involving multiple cell types in ...
Yujing Gao, Jessica L. Brothwood, Harpreet Saini, Gregory A. O'Sullivan, Carla F. Bento, James M. McCarthy, Nicola G. Wallis, Elena Di Daniel, Brent Graham, Daniel M. Tams   +9 more
wiley   +1 more source

Commensal Peptoniphilus harei induce activation of monocytes via TLR2/CD14 signalling in whole blood. [PDF]

Med Microbiol Immunol
Schmidt T, Frick IM, Happonen L, Neumann A.   +3 more
europepmc   +1 more source

TLR2/4-mediated NF-κB pathway combined with the histone modification regulates β-defensins and interleukins expression by sodium phenyl butyrate in porcine intestinal epithelial cells

, 2018
Xiujing Dou, Junlan Han, Qiuyuan Ma, Baojing Cheng, Anshan Shan, Nan Gao, Yuan‐Han Yang   +6 more
openalex   +2 more sources

Granulocyte-derived extracellular vesicles activate monocytes and are associated with mortality in intensive care unit patients [PDF]

, 2018
Adelman, Avril, et al,, Schechtman, Kenneth B, Spinella, Philip C   +3 more
core   +1 more source

The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease

Journal of Clinical Laboratory Analysis, Volume 40, Issue 1, January 2026.
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei, Hamid Pajavand, Razieh Shahbazi, Marzieh Rezaei, Elahe Taki   +4 more
wiley   +1 more source

The effect of combination therapy on Bevacizumab, Carmustine, and Metformin chemotherapy drugs on the fluctuating performance expression of TLR2, TLR6, and IL-6 genes in the cell line of brain glioblastoma. [PDF]

Cancer Cell Int
Norollahi SE, Yousefi B, Yousefzadeh-Chabok S, Nejatifar F, Samadian M, Evazalipour M, Eftekhary M, Akhlaghi MF, Mirzajani E, Rashidy-Pour A, Samadani AA.   +10 more
europepmc   +1 more source

An Integrated Engineering Approach to Creating Health‐Modulating Postbiotics

Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Postbiotics have emerged as a promising alternative to live probiotics, offering comparable health benefits while overcoming challenges related to safety, stability, and shelf life. The review addresses current challenges in standardizing postbiotic definitions and production processes, and by outlining future research directions necessary to unlock ...
Michael Leonidas Chikindas, Diana E. Roopchand, Santosh Kumar Tiwari, Liubov S. Sichel, Mukund V. Karwe, Nitin Nitin, Vitor Luis Fagundes, Igor V. Popov, John R. Tagg, Xuanxuan Lu, Svetoslav Dimitrov Todorov   +10 more
wiley   +1 more source

Detection of Microbial Contamination in Nanomaterials Using LAL, rFC and Cell-Based Assays: Implications for Nanotoxicological Hazard Assessment. [PDF]

Nanomaterials (Basel)
Lei P, Zegeye FD, Alswady-Hoff M, Marcolungo C, Danielsen PH, Madsen AM, Wallin H, Vogel U, Zienolddiny-Narui S, Erdem JS.   +9 more
europepmc   +1 more source

Lymph Node‐Targeted Nanomaterials for Controlled Nano‐Immunotherapy

Small Structures, Volume 7, Issue 1, January 2026.
This study primarily investigates lymph node‐targeted immunotherapeutic strategies, focusing on the mechanisms of immune response regulation within lymph nodes. By targeting distinct immune signaling pathways, we systematically explore the development of nanodrug delivery systems specifically designed for lymph node targeting to achieve enhanced ...
Yitong Zhao, Mengjun Wang, Ming Ma, Yu Zhang, Haoan Wu   +4 more
wiley   +1 more source