Results 171 to 180 of about 237,895 (332)

Litsea salicifolia Roxb. bark ethanolic extract attenuates rheumatoid arthritis by inhibiting TLR4/NF-κB and activating SIRT1-Nrf2/HO-1 signaling axis: In-vitro and in-vivo evaluations

, 2022
Eswara Rao Puppala, Md. Abubakar, Veerabhadra Swamy, Sai Sudha Yalamarthi, Syamprasad NP, Aruna Prakash, Jagadeesh Kumar Gangasani, D. Chamundeswari, V.G.M. Naidu   +8 more
openalex   +1 more source

Selenomethionine Regulates the Arachidonic Acid Metabolism‐Ferroptosis‐Inflammation Axis to Ameliorate Colitis

Animal Research and One Health, EarlyView.
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian, Longzhu Zhou, Xiaohui Feng, Jialu Shen, Xiaoping Du, Qingyu Zhao, Yuchang Qin, Junmin Zhang, Chaohua Tang   +8 more
wiley   +1 more source

Palmitic acid enhances TLR4 expression and promotes resistin/TLR4 signalling [PDF]

Endocrine Abstracts, 2015
Hamza Amine, Yacir Benomar, Arieh Gertler, Mohammed Taouis   +3 more
openaire   +1 more source

Immunological Profiling suggests an Association between Treg dysfunction and Pain in Knee Osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Background Pain is the hallmark symptom of osteoarthritis (OA) and its biological drivers remain poorly understood. While the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular regulatory T cells (Tregs), is not well understood. Methods We performed omics profiling of peripheral blood from 46
Marie Binvignat, Johanna Dubois, Maria Marco Salvador, Paul Stys, Fabien Pitoiset, Alexandra Roux, Michèle Sastre, Signe Hassler, Roberta Lorenzon, Claire Ribet, Vanessa Mhanna, Hélène Vantomme, Leslie Adda, Pierre Barennes, Nicolas Coatnoan, Kenz Le Gouge, Caroline Aheng, Alice Courties, Lise Minssen, Atul J. Butte, Adrien Six, Michelle Rosenzwajg, Nicolas Tchitchek, Francis Berenbaum, David Klatzmann, Encarnita Mariotti‐Ferrandiz, Jérémie Sellam   +26 more
wiley   +1 more source

Genetic Relationship Between Chronic Otitis Media Infection And TLR4 Gene In AL-Qadisyah province, Iraq .

, 2023
Baneen Hissab, Najlaa Abdallah D. Al-Oqaili   +1 more
openalex   +2 more sources

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

Asthma and coagulation [PDF]

, 2013
Hammad, Hamida, Lambrecht, Bart
core   +1 more source

Calcium retinoate nanoparticle mediated microglial polarization to regulate inflammatory microenvironment for therapy of neuroinflammatory disease

BMEMat, EarlyView.
A nano‐drug based on retinoic acid and calcium is developed, which can be rapily endocytosed by microglia and decomposed into small molecule/ion storms in lysosomes. This nano‐drug regulates microglial phenotype switching from M1 to M2 while indirectly guiding neuronal differentiation of endogenous neural stem cells, thereby ameliorating ...
Shuo Zhang, Yuan Yao, Wenfeng Shao, Jiapei Shi, Benjie Wei, Chunhui Sun, Jingang Wang, Jiaming Shi, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Na Ren, Yuchun Tang, Wenjuan Zhou, Shuping Wang   +13 more
wiley   +1 more source

Functional toll-like receptor 4 links endotoxin sensing to platelet priming in feline platelets. [PDF]

Front Vet Sci
Li RHL, Shaverdian M, Chen C, Stuhlmann C, Stern JA, Nguyen N.   +5 more
europepmc   +1 more source

Shanxi Aged Vinegar Protects against Alcohol-Induced Liver Injury via Activating Nrf2-Mediated Antioxidant and Inhibiting TLR4-Induced Inflammatory Response [PDF]

, 2018
Ting Xia, Jin Zhang, Jiahui Yao, Bo Zhang, Wenhui Duan, Chaoya Zhao, Peng Du, Jia Song, Yu Zheng, Min Wang   +9 more
openalex   +1 more source