Results 101 to 110 of about 3,827 (168)

Regulation of TMEM16A altrenatice splincing

, 2012
TMEM16A/Anoctamin1 is a novel calcium-­‐activated chloride channel involved in neuronal and cardiac excitation, vascular tone, pain perception and olfactory and sensory signal transduction and GI tract motility. It is also associated to diverse type of cancer including breast cancer malignancy. Alternative splicing (AS) of exons 6b, 13 and 15 generates
openaire   +1 more source

The role and regulation of TMEM16A in the vascular system

, 2019
TMEM16A is a Ca2+-activated Cl- channel (CaCC) encoded by the TMEM16A gene, expressed in vascular smooth muscle cells (VSMCs). TMEM16A has a proposed role in depolarising the membrane potential (Vm) in response to activation of the Gq-protein coupled receptor (Gq-PCR) signalling cascade.
openaire   +1 more source

ANO1 (TMEM16A) Genetic Variants, Promoter Methylation, and Chloride Dysregulation in Pulmonary Hypertension. [PDF]

J Cardiovasc Dev Dis
Yaman İ, Korkmaz H, Akağaç AE, Kaymaz T, Önder R, Önalan EE.   +5 more
europepmc   +1 more source

Carrier-free procyanidin-ferric nanonetworks loading gefitinib to inhibit TMEM16A-EGFR mutual activation loop for photothermally enhanced breast cancer targeted therapy. [PDF]

Mater Today Bio
Li G, Cai C, Zhang N, Wang Z, Zhang M, Liu Q, Chen S, Shang Y, Zhao C, Ren S, An H.   +10 more
europepmc   +1 more source

Isolation and long-term culture of primary mouse cholangiocytes that retain biophysical properties and distinct Cl-conductances: An initial study. [PDF]

Physiol Rep
Li Q, Wang Y, Boggs K, Kresge C, Nejak-Bowen K.   +4 more
europepmc   +1 more source

TMEM16A in prostate cancer: mechanistic insights and therapeutic implications. [PDF]

Cancer Cell Int
He JW, Li PZ, Huang ZX.
europepmc   +1 more source

Research progress on TMEM proteins in cancer progression and chemoresistance (Review). [PDF]

Int J Mol Med
Shi J, Zheng D, Yao B, Liu Q, Xu H, Piao H.   +5 more
europepmc   +1 more source

Dihydrosanguinarine: A Review of Its Pharmacology, Structure-Activity Relationship, Toxicity, Pharmacokinetics, and Clinical Prospects. [PDF]

Int J Mol Sci
Yin X, Cao Y, Fang C, Zhang C, Yang J, Yu M, Cheng G, Yang L.   +7 more
europepmc   +1 more source

Significance of TMEM16A expression in colorectal carcinoma

World Chinese Journal of Digestology, 2012
Jun Yang, Ni Liu, An-Jing Kang, Shi-Ping Zhao, Xiao-Zhong Huang, Bao-Shan Su, Xiao-Li Chen, Zong-Fang Li   +7 more
openaire   +1 more source

[Transmembrane protein 16A--a new target for the treatment of airway inflammatory diseases]. [PDF]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
Luo Q, Xu N, Tan X.
europepmc   +1 more source