Results 101 to 110 of about 43,824 (207)
Oncology Reports, 2007 Recently, gene fusions between the androgen responsive gene TMPRSS2 and members of the ETS-family of DNA-binding transcription factor genes were found in prostate cancer. Recurrent fusions were identified between the 5'-noncoding region of TMPRSS2 and ERG, or less frequently ETV1 or ETV4, resulting in overexpression of normal or truncated ETS-proteins.
Marta, Winnes +3 more
openaire +3 more sources
Prognostic Histopathological and Molecular Markers on Prostate Cancer Needle-Biopsies: A Review [PDF]
, 2014 Prostate cancer is diverse in clinical presentation, histopathological tumor growth patterns, and survival. Therefore, individual assessment of a tumor's aggressive potential is crucial for clinical decision-making in men with prostate cancer.
Hoogland, A.M. (Marije) +2 more
core +3 more sources
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer. [PDF]
PLoS ONE, 2015 TMPRSS2-ERG junction oncogene is present in more than 50% of patients with prostate cancer and its expression is frequently associated with poor prognosis.
Giorgia Urbinati +6 more
doaj +1 more source
eJHaem, Volume 7, Issue 1, February 2026.ABSTRACT Introduction In Mexico, the 5‐year overall survival (OS) rate for pediatric acute lymphoblastic leukemia (ALL) ranges from 45% to 85%, markedly lower than the ∼90% reported in high‐income countries, where cytogenomic testing is essential for accurate risk stratification and therapeutic decision‐making.
Rosa María González Arreola +8 more
wiley +1 more source
Gene expression analysis of bovine embryonic disc, trophoblast and parietal hypoblast at the start of gastrulation [PDF]
, 2017 In cattle early gastrulation-stage embryos (Stage 5), four tissues can be discerned: (i) the top layer of the embryonic disc consisting of embryonic ectoderm (EmE); (ii) the bottom layer of the disc consisting of mesoderm, endoderm and visceral hypoblast
Berg, D +3 more
core +2 more sources
PSMA PET‐directed radiotherapy for prostate cancer: From precision planning to future innovations
VIEW, Volume 7, Issue 1, February 2026.Prostate‐specific membrane antigen (PSMA) positron emission tomography (PET) imaging enables highly sensitive detection of prostate cancer recurrence and precise lesion mapping. This review summarizes current evidence and emerging applications of PSMA PET in radiotherapy, including diagnostic staging, target delineation, adaptive planning, and outcome ...
Wenpeng Huang +7 more
wiley +1 more source
Cancer stem cells in prostate cancer: implications for targeted therapy [PDF]
, 2017 Prostate cancer (PCa) is the most frequently diagnosed cancer in men and the second most common cause of cancer-related mortality among men in the developed world.
Castelo-Branco, Pedro +5 more
core +1 more source
SARS‐CoV‐2 Chronic Intervillositis: Variations of Maternal Antiviral Response
American Journal of Reproductive Immunology, Volume 95, Issue 2, February 2026.ABSTRACT Problem Placental compromise is a determining factor in the outcome of pregnancies complicated by maternal SARS‐CoV‐2 infection. Chronic histiocytic intervillositis (CHI) is the initial response to SARS‐CoV‐2 infection, but the underlying mechanisms are poorly understood.
Daria Kozlova +8 more
wiley +1 more source
A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon.
PLoS ONE, 2016 Fusion between TMPRSS2 and ERG, placing ERG under the control of the TMPRSS2 promoter, is the most frequent genetic alteration in prostate cancer, present in 40-50% of cases.
Dong Gao +11 more
doaj +1 more source