Results 111 to 120 of about 43,824 (207)
Detection of prostate cancer-specific transcripts in extracellular vesicles isolated from post-DRE urine [PDF]
, 2017 Background: The measurement of gene expression in post-digital rectal examination (DRE) urine specimens provides a non-invasive method to determine a patient’s risk of prostate cancer.
Clark, Jeremy +9 more
core +1 more source
Humoral epitope dominance and immune imprinting by SARS‐CoV‐1 and SARS‐CoV‐2 vaccines
Immunology &Cell Biology, Volume 104, Issue 2, Page 150-167, February 2026.We investigated Modified Vaccinia Ankara (MVA) vaccine candidates expressing the SARS‐CoV‐1 or SARS‐CoV‐2 Spike, as a primary or booster immunization, for their ability to induce antibodies targeting different epitopes on the SARS‐CoV‐2 RBD and broad cross‐reactive or cross‐neutralizing responses in C57BL/6 and antibody humanized (Ig‐humanized) mice ...
Deborah L Burnett +17 more
wiley +1 more source
DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II [PDF]
, 2019 DNA double strand breaks (DSBs) are the most cytotoxic lesions of those occurring in the DNA and can lead to cell death or result in genome mutagenesis and chromosomal translocations.
Gómez Herreros, Fernando
core +2 more sources
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.The Goto‐Kakizaki rat, a non‐obese model of type 2 diabetes mellitus (T2DM), exhibits lymphoid organ remodeling, including baseline thymic involution and splenic white pulp reorganization. Following completion of a three‐dose SARS CoV‐2 antigen immunization protocol, anti‐Spike IgG levels were significantly increased despite these structural changes ...
Sara Araujo Pereira +11 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhiyong Zhang +5 more
wiley +1 more source
Addressing Sex and Gender Bias in COVID-19 Epidemiology in Bangladesh
Journal of Agriculture, Food and Environment, 2021 Sex and gender are recognized as a vital factor in the infectious disease epidemiology,and disease outcomes,and these two factors also appear to hold for severe acute respiratory syndrome (SARS-CoV-2)infection.
M. A. Islam
doaj +1 more source
lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs. [PDF]
, 2013 Although recent studies have indicated roles of long non-coding RNAs (lncRNAs) in physiological aspects of cell-type determination and tissue homeostasis, their potential involvement in regulated gene transcription programs remains rather poorly ...
Evans, Christopher P +11 more
core
Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids [PDF]
, 2019 Mutations in the gene encoding the type II transmembrane protease 3 (TMPRSS3) cause human hearing loss, although the underlying mechanisms that result in TMPRSS3-related hearing loss are still unclear.
Alex, Alpha L. +8 more
core +1 more source
Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy. [PDF]
, 2017 Androgen receptor (AR) signaling remains the major oncogenic pathway in prostate cancer (PCa). Androgen-deprivation therapy (ADT) is the principle treatment for locally advanced and metastatic disease.
Cucchiara, Vito +5 more
core +2 more sources
Genomic Alteration Burden in Advanced Prostate Cancer and Therapeutic Implications. [PDF]
, 2019 The increasing number of patients with sequenced prostate cancer genomes enables us to study not only individual oncogenic mutations, but also capture the global burden of genomic alterations.
Bose, Rohit, Ryan, Matthew J
core +1 more source