Results 41 to 50 of about 43,824 (207)
Impact TMPRSS2–ERG Molecular Subtype on Prostate Cancer Recurrence [PDF]
Life, 2021 Currently, seven molecular subtypes of prostate cancer (PCa) are known, the most common of which being the subtype characterized by the presence of the TMPRSS2–ERG fusion transcript. While there is a considerable amount of work devoted to the influence of this transcript on the prognosis of the disease, data on its role in the progression and prognosis
Anastasiya A. Kobelyatskaya +15 more
openaire +3 more sources
Frontiers in Genetics, 2020 Type 2 transmembrane serine protease (TMPRSS2) is a new member of the serine proteases, and studies have shown that TMPRSS2 plays a role in the occurrence of prostate malignancies and is closely related to the occurrence of the coronavirus disease 2019 ...
Lianxiang Luo +8 more
doaj +1 more source
Characterization of the Hemagglutinin Cleaving Transmembrane Serine Proteases Matriptase and TMPRSS2 [PDF]
, 2019 Influenza is one of the commonest infectious diseases affecting millions of people every year including 290,000 – 650,000 heavy casualties. Influenza viruses undergo constant genetic changes and every 10 – 50 years new influenza virus strains emerge that
Keils, Aline
core +1 more source
TMPRSS2 (transmembrane protease, serine 2) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on TMPRSS2 (transmembrane protease, serine 2), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire +2 more sources
Scientific Reports, 2022 The cell surface serine protease Transmembrane Protease 2 (TMPRSS2) is required to cleave the spike protein of SARS-CoV-2 for viral entry into cells. We determined whether negatively-charged heparin enhanced TMPRSS2 inhibition by alpha-1-antitrypsin (AAT)
Xiyuan Bai +13 more
doaj +1 more source
The use of equine influenza pseudotypes for serological screening [PDF]
, 2012 Standard assays used for influenza serology present certain practical issues, such as inter-laboratory variability, complex protocols and the necessity for handling certain virus strains in high biological containment facilities.
Böttcher-Friebertshäuser, Eva +5 more
core +4 more sources
Development of a multivariable risk model integrating urinary cell DNA methylation and cell-free RNA data for the detection of significant prostate cancer [PDF]
, 2020 Background: Prostate cancer exhibits severe clinical heterogeneity and there is a critical need for clinically implementable tools able to precisely and noninvasively identify patients that can either be safely removed from treatment pathways or those ...
Bapat, Bharati +11 more
core +1 more source
ETS-TMPRSS2 fusion gene products in prostate cancer [PDF]
Cancer Biology & Therapy, 2006 Genes playing a role in carcinogenesis have often been identified through analysis of recurrent chromosomal rearrangements. Although such rearrangements are well known in leukemias, lymphomas, and sarcomas, they have not been well characterized in carcinomas. In the October 28, 2005 issue of Science, a study by Tomlins et al.
Christoph M, Ahlers, William D, Figg
openaire +2 more sources
TMPRSS2 is a functional receptor for human coronavirus HKU1
Nature, 2023 Four endemic seasonal human coronaviruses causing common colds circulate worldwide: HKU1, 229E, NL63 and OC43 (ref. 1). After binding to cellular receptors, coronavirus spike proteins are primed for fusion by transmembrane serine protease 2 (TMPRSS2) or endosomal cathepsins2-9.
Saunders, Nell +28 more
openaire +2 more sources
Bromhexine is a potential drug for COVID-19; From hypothesis to clinical trials
Вопросы вирусологии, 2022 COVID-19 (novel coronavirus disease 2019), caused by the SARS-CoV-2 virus, has various clinical manifestations and several pathogenic pathways. Although several therapeutic options have been used to control COVID-19, none of these medications have been ...
S. Bahadoram +6 more
doaj +1 more source