Results 181 to 190 of about 621,434 (269)
ABSTRACT Background Canine atopic dermatitis (cAD) is a genetically, aetiologically, immunologically and clinically complex disease requiring both individualised immediate and long‐term management. Objectives These updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA) aim to substantially revise previous ...
Ralf S. Mueller +4 more
wiley +1 more source
Thomsen-Friedenreich antigen (T antigen) has been supposed to be a cancer-specific carbohydrate antigen. We have previously shown that one third of the Japanese population normally expressed T antigen in gastric surface epithelia and the other two thirds
Tsuji, Takao +4 more
core
Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activation. [PDF]
Liu Z +10 more
europepmc +1 more source
Abstract Background and Objectives Availability of new technologies has accelerated the pace of blood group discovery, with nine of 48 known systems being discovered in the past 5 years alone, and yet uncharacterized antigens remain. This study involved investigations of samples from a female patient presenting with a moderate strength pan‐reactive ...
Tosti J. Mankelow +7 more
wiley +1 more source
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to its asymptomatic progression, late‐stage diagnosis, and treatment resistance. Efforts in early detection have centered on identifying imaging features and liquid biopsy biomarkers capable of detecting PDAC and its high‐grade precursors before clinical symptoms ...
Christine Worthington +105 more
wiley +1 more source
Objective Initially described in 1976, X‐linked dystonia parkinsonism (XDP) is a neurodegenerative disease that can be characterized by the presentation of dystonia and parkinsonism symptoms. Although this disease bears some resemblance to other neurodegenerative diseases in terms of symptomatology, the pathological signature of XDP is still unclear ...
Adelie Y.S. Tan +19 more
wiley +1 more source
Association of Clonal Hematopoiesis With Incident, Late‐Onset, Seropositive Rheumatoid Arthritis
Objective Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, CH of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA) and whether ...
Kun Zhao +8 more
wiley +1 more source
CCNE1: A Cell Cycle Regulator That Influences Tumor Progression
ABSTRACTCyclin E1 (CCNE1), a pivotal member of the cyclin family, governs the G1/S phase transition of the cell cycle by binding to and activating cyclin‐dependent kinase 2 (CDK2), thereby initiating DNA replication and driving S‐phase entry. In a broad spectrum of human malignancies—including breast, ovarian, gastric, and non‐small cell lung cancers ...
Liang Yan +6 more
wiley +1 more source
Abstract Background Ciltacabtagene autoleucel (cilta‐cel), an anti–B‐cell maturation antigen (BCMA) chimeric antigen receptor T‐cell (CAR‐T) therapy, is approved for relapsed/refractory multiple myeloma (RRMM). Methods Using the Center for International Blood and Marrow Transplant Research registry, this study evaluated outcomes of frail patients ...
Hira Mian +31 more
wiley +1 more source
Incorporation of Tn Antigen Mimetics into the MUC1
Carmen Breton +4 more
openaire +2 more sources

