Results 81 to 90 of about 583,823 (157)
, 2023 The aim of this study is to elucidate the molecular background of SARS-CoV-2 (COVID-19) pathogenesis, focusing on complex N- and O-glycozylation pathways and the interaction of human ABO(H) blood grouping enzymes with virus binding to cell surfaces and ...
Peter Arend (560469)
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Towards the Synthesis of a C-glycoside Serine Tn Antigen [PDF]
Sustainable IndustryTowards the Synthesis of a C-glycoside Serine Tn Antigen Thomson Ly, Advait Desai, Iraj Sadraei, John F. Trant Many biological processes including bacterial and viral infections (notably HIV and the flu), immunogenic responses, and ...
Ly, Thomson
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, 2023 The pathogenesis of SARS-CoV-2 disease may be characterised by a complex of genetically undefined N- and O-glycosylations, while O-GalNAc glycans and O-linked sialoglycans have been identified as essential viral receptors.
Peter Arend (560469)
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Simple mucins (T, sialosyl-T, Tn and sialosyl-Tn) are not diagnostic for malignant breast lesions
, 1994 Immunohistochemical study of the distribution of carbohydrate core-structures on O-linked glycoproteins (T, sialosyl-T, Tn and sialosyl-Tn) was performed using specific monoclonal antibodies on 148 primary breast lesions, including 10 normal breast ...
Bryne, M. +8 more
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Immunohistochemical study of Tn, sialosyl-Tn and T antigens in human meningiomas.
European journal of histochemistry : EJH, 1998 Since an aberrant glycosylation associated with abnormal expression of cell surface carbohydrates has been described in many human tumours, we have investigated the expression of simple mucintype carbohydrate antigens (Tn, sialosyl-Tn and T) in 30 formalin-fixed paraffin-embedded surgical specimens of primary meningiomas, subdivided according to the ...
GIUFFRE', Giuseppe +3 more
openaire +2 more sources
Transplant nephrectomy - A single-center experience
Saudi Journal of Kidney Diseases and Transplantation, 2015 Transplant nephrectomy (TN) is associated with significant morbidity and mortality and influences the outcome of subsequent renal transplantation. The aim of this study was to identify the reasons for TN in a single transplant center in the United ...
Arun Ariyarathenam +2 more
doaj +1 more source
SYNTHETIC VACCINES .1. SYNTHESIS OF MULTIVALENT TN ANTIGEN CLUSTER-LYSYLLYSINE CONJUGATES
, 1990 SYNTHETIC VACCINES .1.
T TOYOKUNI (21031199) +2 more
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Phage Display Reveals VLRB-Mediated Recognition of Minimal Tumor Glycan Antigen Sialyl-Tn
Current Issues in Molecular BiologySialyl-Tn (sTn) is a tumor-associated carbohydrate antigen (TACA) abundantly expressed by various types of carcinomas. While conventional antibody-based platforms have traditionally been used for the detection and targeting of sTn, alternative binding ...
Mark Rickard N. Angelia +8 more
doaj +1 more source
The crystal structure of a plant lectin in complex with the Tn antigen.
, 2003 International audienceThe structure of the tetrameric Vicia villosa isolectin B4 (VVLB4) in complex with a cancer antigen, the Tn glycopeptide (GalNAc-O-Ser), was determined at 2.7 A resolution.
Bay, Sylvie +11 more
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Aim: Fluorescence detection of breast and prostate cancer cells expressing Tn-antigen, a tumor marker, with Vicia villosa lectin (VVL)-labeled nanoparticles. Materials & methods: Breast and prostate cancer cells engineered to express high levels of Tn-
Kimani, Martha Wamaitha +6 more
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