Results 211 to 220 of about 621,791 (286)

Piper nigrum Has an Antitumor Effect Through Regulation of the Phosphatidylinositol 3‐Kinase Signaling Pathway in a Murine Model of Acute Myeloid Leukemia

Phytotherapy Research, Volume 40, Issue 10, Page 5988-6004, October 2026.
Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo, Paola Lasso, Claudia Urueña, Susana Fiorentino   +3 more
wiley   +1 more source

Structural Basis of a High-Affinity Antibody Binding to Glycoprotein with Glycocalyx Decay. [PDF]

JACS Au
Bin Han Y, Niu J, Pan D, Feng C, Song K, Meng B, Zhu S, Behren S, Westerlind U, Zhang Y, Liu H, Xu L, Zhou D.   +12 more
europepmc   +1 more source

Tn Antigen-MUC1-32mer Antibody [PDF]

, 2020
openaire   +1 more source

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection

Journal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun, Muhammed Duman, Jesús L. Romalde, Nihed Ajmi, Gorkem Tasci, Cuneyt Ozakin, Nazmiye Ulku Tuzemen, Bekir Akça, Sebahattin Ergün, Sevdan Yılmaz, Izzet Burcin Saticioglu   +10 more
wiley   +1 more source

From Glycocode to Precision Oncology: Therapeutic Strategies Targeting Aberrant O-GalNAc Glycosylation in Cancer. [PDF]

Chem Rev
Aasted MKM, Jaroentomeechai T, Dabelsteen S, Joshi H, Stowell SR, Wandall HH.   +5 more
europepmc   +1 more source

Understanding the Immune Response Changes to Clinical Interventions for Epstein–Barr Virus Infection Prior to Lymphoma Development in Children After Organ Transplants (UNEARTH)

Pediatric Transplantation, Volume 30, Issue 10, October 2026.
The T cell and Natural Killer cell immune responses in primary EBV infection in children or during progression to PTLD are not well characterized. By performing detailed prospective immunological phenotyping through the first year after 278 pediatric organ transplants, we will unearth pathways that may inform EBV oncogenesis progression.
Vikas R. Dharnidharka, Claire Bocchini, Swati Choudhry, Elizabeth Moulton, Lujain Jaza, Joseph Dumayas, Camila Macedo, Elizabeth Zaragoza, Maryam Mysorewala, Michelle Becker‐Hapak, Mark Foster, Mansi Agarwal, Charles W. Goss, Kenneth B. Schechtman, Kate Nolt, Juan Diego Ramirez, Eileen Rios‐Abdallah, Raja Dandamudi, Michael Green, Kristine M. Wylie, Todd A. Fehniger, Diana Metes, Lara Danziger‐Isakov   +22 more
wiley   +1 more source

Chemoimmunotherapy‐associated CD20 (MS4A1) resistance mutations in Waldenström macroglobulinemia: Epitope disruption independent of expression with implications for CD20‐directed cellular therapies

HemaSphere, Volume 10, Issue 10, October 2026.
Alberto Guijosa, Nickolas Tsakmaklis, Sirano Dhe‐Paganon, Filip Garbicz, Ruben Carrasco, John Hatcher, Andres Ramirez‐Gamero, Dominic Pizzarella, Amanda Kofides, Shirong Liu, Hao Sun, Xia Liu, María L. Guerrera, Andrew R. Branagan, Gottfried von Keudell, Shayna R. Sarosiek, Jorge J. Castillo, Zachary R. Hunter, Steven P. Treon   +18 more
wiley   +1 more source

Pathological Evolution of Fibrosis in IgG4‐Related Ophthalmic Disease: A Retrospective Study of 100 Cases

Pathology International, Volume 76, Issue 10, October 2026.
IgG4‐related ophthalmic disease comprises four histologic patterns representing progressive fibrosis and sclerosis. Fibrosis is associated with CD163‐positive M2 macrophages and increased TGFB1 expression in lymphocyte‐rich areas, suggesting roles for these components in disease progression.
Natsuki Taniguchi, Akira Satou, Yasuharu Sato, Taishi Takahara, Yasuhiro Takahashi, Toshinobu Kubota, Akari Iwakoshi, Toyonori Tsuzuki   +7 more
wiley   +1 more source

Molecular Engineering Boosts Photon‐Activated Immunotherapy for Prostate Cancer Through Concurrent Pyroptosis and cGAS‐STING Pathway Activation

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
The engineered DTSe‐based photosensitizer, DZTSe, emerges as an avant‐garde molecular entity, which can distribute to both the endoplasmic reticulum and mitochondria to concurrently trigger pyroptosis and activate the cGAS‐STING pathway. This dual‐action strategy effectively reprograms the tumor microenvironment, enabling potent eradication of primary ...
Cheng Zhang, Xiaolan Yin, Jeongyeon Hong, Qixian Chen, Weijie Chi, Jingyun Wang, Juyoung Yoon, Haidong Li   +7 more
wiley   +2 more sources