Results 231 to 240 of about 81,953 (280)

Expression of the Tn antigen in myelodysplasia, lymphoma, and leukemia

open access: yesTransfusion, 1992
Expression of the normally cryptic blood group antigen Tn has occasionally been reported in hematologic disease, but the true frequency of this change is not known. A mouse monoclonal antibody (FBT3) and immunohistochemistry were used to examine expression of the Tn antigen.
D J, Roxby   +3 more
openaire   +3 more sources

Detection of Tn, sialyn-Tn and T antigens in HNPCC

open access: yes, 1996
The simple mucin-type carbohydrate antigens Tn, sialosyl-Tn, T and the 'cryptic' sialylated variant of the last represent the mucin core oligosaccharide structures that are produced in the initial steps of the mucin biosynthetic pathway. Utilizing monoclonal antibodies anti-Tn antigen (HB-Tn1), anti-sialosyl-Tn antigen (HB-STn1), anti-T antigen (HB-T1)
G. GIUFFRÈ   +4 more
openaire   +2 more sources

Tn and Sialyl‐Tn antigens in canine gastric tissues

Veterinary and Comparative Oncology, 2020
AbstractMalignant transformation is often associated with abnormal protein glycosylation expressed, amongst others, by the accumulation of simple mucin‐type carbohydrates namely Tn and Sialyl‐Tn (STn) antigens. These are usually limited in normal tissues and their increased expression has been associated with cancer progression and poor prognosis. This
Ana R. Flores   +7 more
openaire   +2 more sources

Expression of Tn and Sialyl-Tn Antigens in Tumor Tissues of the Ovary

American Journal of Clinical Pathology, 1991
The expression of sialyl-Tn and Tn antigens in various benign, borderline, and malignant ovarian tumors was examined immunohistochemically using newly developed antibodies specific for sialyl-Tn and Tn antigens. Sialyl-Tn antigen was detected in only one benign tumor, a mucinous adenoma that showed faint cytoplasmic staining in a few cells.
M, Inoue   +3 more
openaire   +2 more sources

Expression of Tn, sialosyl Tn, and T antigens in human pancreas

Gastroenterology, 1991
Carbohydrate antigens representing some of the initial steps in mucin O-linked glycosylation were examined in specimens of normal pancreas, chronic pancreatitis, and pancreatic adenocarcinoma. Tn antigen, recognized by Vicia villosa lectin, was expressed by all specimens of normal pancreas (acinar cells) and pancreatic cancers and all but one case of ...
S, Itzkowitz   +5 more
openaire   +2 more sources

Coexpression of cancer-associated carbohydrate antigens, Tn and sialyl Tn

Glycoconjugate Journal, 1994
The expression of cancer-associated antigens, Tn and sialyl Tn, was examined using monoclonal antibodies, MLS 128 and MLS 102, recognizing these two antigens, respectively. A cell lysate from a human carcinoma cell line, LS 180 cells, was analysed by Western blotting using these two antibodies.
H, Nakada   +3 more
openaire   +2 more sources

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