Results 141 to 150 of about 1,383,229 (318)

TNF-α mRNA and protein expression outcome after two-challenge intervention: IRAK3 knockout group versus IRAK3 wildtype group.

, 2022
Mice underwent CLP; at 24h (ST) after CLP mice were inoculated with P. aeruginosa, and at 6h (IT) after second challenge TNF-α mRNA expression was measured, and at 24h (LT) for protein expression measured [36].
Ilona Turek (7224899), Terri Meehan-Andrews (6409574), Trang H. Nguyen (12090814), Helen R. Irving (9160614), Anita Zacharias (5052908)   +4 more
core   +1 more source

Role of TNF α, IL-6 and CXCL10 in Dengue disease severity

Iranian Journal of Microbiology, 2018
Background and Objectives: Dengue virus infections (Dengue) have become increasingly common in Pakistan and can result in case fatalities if not managed appropriately. Patients with Dengue virus infection may be asymptomatic or present with Dengue fever (
Kiran Iqbal Masood, Bushra Jamil, Maryam Rahim, Muniba Islam, Muhammad Farhan, Zahra Hasan   +5 more
doaj  

TNFα Induces DNA and Histone Hypomethylation and Pulmonary Artery Smooth Muscle Cell Proliferation Partly via Excessive Superoxide Formation

Antioxidants
Objective: The level of tumor necrosis factor-α (TNF-α) is upregulated during the development of pulmonary vascular remodeling and pulmonary hypertension. A hallmark of pulmonary arterial (PA) remodeling is the excessive proliferation of PA smooth muscle
Patrick Crosswhite, Zhongjie Sun
doaj   +1 more source

KORELASI KADAR CRP, TNF-α DAN BONE MINERAL DENSITY DENGAN CARBOXYTERMINAL CROSSLINKED TELOPEPTIDE TYPE I OF COLLAGEN DI PENDERITA ARTRITIS REUMATOID

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018
Rheumatoid Arthritis (RA) is a systemic autoimmune disease accompanied by decreasing bone mass density and ultimately leads toosteoporosis. The cause of decreased bone mass density is still unknown, but the inflammation has been suspected as an important factor.The correlation between the severity of inflammation with the decrease in bone mass density ...
Kusworini Handono, BP Putra Suryana, Sulistyorini Sulistyorini   +2 more
openaire   +2 more sources

TNF-α activates autophagy in A7r5 cells through an-IKKα dependent pathway.

, 2018
(A) Western blot analysis of Beclin1, p62, LC3-II and GAPDH in A7r5 cells stimulated with 0, 1, 10 and 100 ng/mL of TNF-α (n = 4; *pB) Western blot analysis of Beclin1, p62, LC3-II and GAPDH in A7r5 cells incubated with TNF-α (100 ng/mL) at 0, 3, 16, 24 ...
Nicole Cancino-Arenas (5210993), Jaime A. Riquelme (2967201), Constanza Nuñez-Soto (5210996), Fernanda Sanhueza-Olivares (5211002), David Mondaca-Ruff (5211005), Alejandra San Martín (484118), Ignacio Norambuena-Soto (5211011), Marina García-Miguel (5210999), Pablo E. Morales (5211008), Mario Chiong (2179764)   +9 more
core   +1 more source

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

Arthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J. T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source

Circulating TNF-α levels in rheumatoid arthritis: a systematic review and meta-analysis and comparison to TNF-α levels in sepsis

Therapeutic Advances in Infectious Disease
Background: Tumor necrosis factor-alpha (TNF-α) is implicated in the pathogenesis of autoimmune conditions and sepsis. Although anti-TNF-α therapies have demonstrated clinical efficacy in rheumatoid arthritis (RA), there is no established evidence for ...
Sias Scherger, Andrés F. Henao-Martinez, Carlos Franco-Paredes, Binh T. Ngo, Alyssa Grimshaw, Ranjit Sah, Sangam Shah, Stefan Sillau, Alfonso G. Bastias, Michaele Francesco Corbisiero, Hannah M. Kyllo, Jordan Stellern, Leland Shapiro   +12 more
doaj   +1 more source

Forward and Reverse Signaling Mediated by Transmembrane Tumor Necrosis Factor-Alpha and TNF Receptor 2: Potential Roles in an Immunosuppressive Tumor Microenvironment

Frontiers in Immunology, 2017
Tumor necrosis factor-alpha (TNF-α) is a pleiotropic inflammatory cytokine produced mainly by activated macrophages, lymphocytes and other cell types. Two distinct forms of TNF-α have been identified: soluble TNF-α (sTNF-α) and transmembrane TNF-α (mTNF ...
Yang Qu, Yang Qu, Yang Qu, Gang Zhao, Gang Zhao, Gang Zhao, Hui Li, Hui Li, Hui Li   +8 more
doaj   +1 more source

TNF-α-dependent loss of monolayer resistance in HDMEC does not depend on SFK activity.

, 2016
A, Three days after cells were seeded at confluence on 8W10E ECIS electrodes, complete growth media was replaced by EBM-2 containing 0.3% FBS and incubated for another 16 hours. Then, cells were treated with different amounts of TNF-α (as shown). TEER at
Nina Martino (3108468), Hiba Alsaffar (119795), Anthony M. Lowery (358495), Peter A. Vincent (3108471), Alejandro P. Adam (55143)   +4 more
core   +1 more source

Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study

Arthritis Care &Research, EarlyView.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij, Ilja Tchetverikov, Marc R. Kok, Marijn Vis, Yvonne Goekoop‐Ruiterman, Jessica Bijsterbosch, Paul Baudoin, Reinhard Bos, Jos H. van der Kaap, Petra Kok, Lindy‐Anne Korswagen, Jolanda J. Luime   +11 more
wiley   +1 more source