Results 141 to 150 of about 3,516,666 (358)

Tumor nekrózis faktor-alfa (TNF-α) szerepe

, 2015
A TNF-α egy gyulladást keltő citokin, amelynek kettő formája ismert, egy szolubilis és egy membrán kötött. Részt vesznek a fertőzés és a daganatok elleni védekezésben, a sejtek túlélésének szabályozásában, illetve a homeosztázis fenntartásában is ...
Nemes, Olívia
core  

TNF-α profile over time post-injection.

, 2019
(A) Extracellular and (B) intracellular concentrations (pg/mg of total protein) of TNF-α are represented over time p.i.: 0h (for vehicle-injected mice), 1h, 5h, 10h, 1 day, 2 days, 5 days, and 8 days.
Joaquim Martí-Clúa (6786698), Sandra Villegas (566431), Gisela Esquerda-Canals (4329706)   +2 more
core   +1 more source

The Development and Preclinical Assessment of Ovine Anti-TNF-α Polyclonal Antibodies for the Oral Treatment of Inflammatory Bowel Disease

, 2022
   Tumour Necrosis Factor-alpha (TNF-α) is one of the main drivers of inflammatory bowel disease (IBD). Regulating the actions of this pro-inflammatory cytokine through selective antagonism using an anti-TNF-α monoclonal antibody (mAb) provides effective
Owen Rees Griffiths (13040982)
core   +1 more source

Pengaruh Ekstrak Metanol Biji Mahoni terhadap Peningkatan Kadar Insulin, Penurunan Ekspresi TNF-αdan Perbaikan Jaringan Pankreas Tikus Diabetes

Jurnal Kedokteran Brawijaya, 2013
Diabetes mellitus(DM) merupakan penyakit gangguan metabolisme yang ditandai dengan meningkatnya kadar glukosa darah  (hiperglikemia)  akibat  gangguan  sekresi  insulin  dan  atau  meningkatnya  resistensi  insulin.  T erapi  ekstrak  metanol  biji mahoni (Swetenia  mahagoni Jacq)  merupakan  salah  satu  pengobatan  alternatif  ...
Nany Suryani, Tinny Endang H, Aulanni'am Aulanni'am   +2 more
openaire   +2 more sources

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

TNF-α expression in peribronchovascular areas and bronchiolar epithelial cells.

, 2019
The numbers of TNF-α+ cells in peribronchovascular areas (A) and the TNF gene expression levels in bronchiolar epithelial cells (B) obtained for the Control groups after 1 (n = 10 and 5, respectively), 3 (n = 6 and 5, respectively), and 6 (n = 7 and 4 ...
Rildo Aparecido Volpini (602014), Elia Garcia Caldini (3139689), Ana Paula Pereira Velosa (3139671), Natália Gomes Gonçalves (6195602), Milton de Arruda Martins (6195614), Thais Mauad (84910), Chin Jia Lin (6195605), Mariangela Macchione (6195617), Juliana Tiyaki Ito (6195593), Juliana Dias Lourenço (6195599), Iolanda de Fátima Lopes Calvo Tibério (6195611), Gilles Landman (2137852), Daniela Aparecida de Brito Cervilha (6195596), Walcy Paganelli Rosolia Teodoro (6195608), Fernanda Degobbi Tenorio Quirino dos Santos Lopes (6195620)   +14 more
core   +1 more source

Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva

Advanced NanoBiomed Research
Tumor necrosis factor‐α (TNF‐α) has emerged as a critical biomarker for insulin resistance and diabetic complications, offering an alternative avenue for diabetes management beyond conventional glucose monitoring.
Mingjie Yang, Ying Zhi Cheong, Chenglong Xu, Sanje Mahasivam, Xudong Cai, Vipul Bansal, Sharath Sriram, Ganganath Perera, Madhu Bhaskaran   +8 more
doaj   +1 more source

A complex epigenetic switching is critical for TNF-α upregulation in prefrontal cortex of suicide subjects

American Journal of Psychiatry, 2018
OBJECTIVE Pro-inflammatory cytokines have recently received considerable attention for their roles in suicidal behavior; however, how the expression of cytokine genes is regulated is not clearly known.
Qingzhong Wang, B. Roy, G. Turecki, R. Shelton, Yogesh K. Dwivedi   +4 more
semanticscholar   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

IL-6 and TNF-α promote metastasis of lung cancer by inducing epithelial-mesenchymal transition

Oncology Letters, 2017
The characteristics of cancer cells, such as invasiveness, are affected by the tumor microenvironment. Studies have shown that interleukin (IL)-6 and tumor necrosis factor (TNF)-α regulate the proliferation of lung cancer.
G. Shang, Lun-Xu Liu, Yiyin Qin
semanticscholar   +1 more source