Results 121 to 130 of about 1,383,229 (318)

Electric foot-shock stress drives TNF-alpha production in the liver of IL-6-deficient mice

, 2004
Objectives: Accumulating evidence has shown that interleukin-6 (IL-6) has pleiotropic effects on a variety of biological functions, including its antiapoptotic potential during liver injury.
Chida, Y, Motomura, Y, Kubo, C, Sudo, N
core  

TNF-α profile over time post-injection.

, 2019
(A) Extracellular and (B) intracellular concentrations (pg/mg of total protein) of TNF-α are represented over time p.i.: 0h (for vehicle-injected mice), 1h, 5h, 10h, 1 day, 2 days, 5 days, and 8 days.
Joaquim Martí-Clúa (6786698), Sandra Villegas (566431), Gisela Esquerda-Canals (4329706)   +2 more
core   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

TNF-α enhances Th9 cell differentiation and antitumor immunity via TNFR2-dependent pathways

Journal for ImmunoTherapy of Cancer, 2019
Tumor specific Th9 cells are potential effector cells for adoptive therapy of human cancers. TNF family members OX40L, TL1A and GITRL have been shown to promote the induction of Th9 cells and antitumor immunity.
Yuxue Jiang, Jintong Chen, Enguang Bi, Yinghua Zhao, Tianxue Qin, Yiming Wang, Alison Wang, Sujun Gao, Qing Yi, Siqing Wang   +9 more
doaj   +1 more source

PENGARUH LATIHAN BEBAN PADA LANSIA TERHADAP KADAR TNF-α

Jurnal e-Biomedik, 2015
Abstract: In elderly, the biological function of the systems in human body will decrease. Physical exercise is a systematical and programmed exercise to increase the body function and skills. Overtraining will influence the inflammatory response marked by the release of proinflammatory cytokines inter alia TNF-α.
Kilapong, Russell B. J. D., Supit, Siantan, Rampengan, J. J. V.   +2 more
openaire   +3 more sources

High Dose (5mg) Daily Folic Acid Supplement in Healthy Brazilian Volunteers Increases Mononuclear TNF-α Expression and Reduces NK Cell Number and Activity

Blood, 2015
Abstract Background In Brazil, wheat and corn flour is fortified with 150 µg of folic acid (FA), the synthetic form of folate. Individuals with increased cell duplication, including pregnant women and patients with hemolytic anemia need increased amounts of folate.
Juliano Bertinato, Clovis Paniz, Maylla Rodrigues Lucena, Patrícia Mendonça da Silva Amorim, Guilherme Wataru Gomes, Maria Stella Figueiredo, Ralph Green, Elvira Maria Guerra Shinohara   +7 more
openaire   +1 more source

Schematic diagram showing the possible mechanism of anti-TNF-α therapy in polycystic ovary syndrome (PCOS).

, 2019
Persistent exposure to androgen promoted the secretion of TNF-α and other inflammatory factors. TNF-αsignificantly upregulated CYP17A1 and downregulated CYP19A1, the key enzymes involved in the synthesis and conversion of androgens, leading to the ...
Xie Yidong (6807866), Xu Wenming (652821), Zuo Tao (6807875), Zhang Xueguang (6807869), Qin Lang (2902367), Wu Sixian (6807872)   +5 more
core   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Efek Ekstrak Propolis terhadap Ekspresi TNF-α, Apoptosis dan Nekrosis Jaringan Otak Tikus Model Traumatic Brain Injury (TBI)

Jurnal Kedokteran Brawijaya, 2016
Ekstrak propolis merupakan produk lebah dengan berbagai kandungan aktif yang memiliki efek antioksidan, antiinflamasi, proteksi DNA, neuroprotektan dan immunomodulator. Propolis mampu menurunkan reaksi inflamasi melalui hambatan terhadap aktivitas TNF-α dan NF-κB, mampu menurunkan Bax dan caspase-3, dan meningkatkan Bcl-2, yang berperan pada jalur ...
Ashalia Chandra Dewi, Mulyohadi Ali, Hari Purnomo   +2 more
openaire   +2 more sources

Estudo de polimorfismos genéticos do HLA (classes I e II) e do TNF-α em doentes com sarcoidose

Revista Portuguesa de Pneumologia, 2008
Resumo: Introdução: A susceptibilidade genética na ocorrência da sarcoidose é sugerida por alguns factores, nomeadamente pela observação de casos de agregação familiar e a associação da raça a diferentes tipos de incidência e gravidade da doença.
António Morais, Helena Alves, Bruno Lima, Luís Delgado, Ricardo Gonçalves, Sandra Tafulo   +5 more
openaire   +2 more sources