Results 131 to 140 of about 1,383,229 (318)

Tumor nekrózis faktor-alfa (TNF-α) szerepe

, 2015
A TNF-α egy gyulladást keltő citokin, amelynek kettő formája ismert, egy szolubilis és egy membrán kötött. Részt vesznek a fertőzés és a daganatok elleni védekezésben, a sejtek túlélésének szabályozásában, illetve a homeosztázis fenntartásában is ...
Nemes, Olívia
core  

TNF-α expression in peribronchovascular areas and bronchiolar epithelial cells.

, 2019
The numbers of TNF-α+ cells in peribronchovascular areas (A) and the TNF gene expression levels in bronchiolar epithelial cells (B) obtained for the Control groups after 1 (n = 10 and 5, respectively), 3 (n = 6 and 5, respectively), and 6 (n = 7 and 4 ...
Rildo Aparecido Volpini (602014), Elia Garcia Caldini (3139689), Ana Paula Pereira Velosa (3139671), Natália Gomes Gonçalves (6195602), Milton de Arruda Martins (6195614), Thais Mauad (84910), Chin Jia Lin (6195605), Mariangela Macchione (6195617), Juliana Tiyaki Ito (6195593), Juliana Dias Lourenço (6195599), Iolanda de Fátima Lopes Calvo Tibério (6195611), Gilles Landman (2137852), Daniela Aparecida de Brito Cervilha (6195596), Walcy Paganelli Rosolia Teodoro (6195608), Fernanda Degobbi Tenorio Quirino dos Santos Lopes (6195620)   +14 more
core   +1 more source

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang, Shuang Liu, Jiale Wang, Kaiyang Xue, Shenwei Li, Zhongheng Du   +5 more
wiley   +1 more source

Quantitative comparison of the neutralizing capacity, immunogenicity and cross-reactivity of anti-TNF-α biologicals and an Infliximab-biosimilar.

PLoS ONE, 2018
IntroductionTNF-α-neutralizing antibodies, such as infliximab (IFX) and adalimumab (ADA), are effective in the treatment of inflammatory bowel diseases (IBD), but they are expensive and become ineffective when patients develop anti-IFX or anti-ADA ...
D J Buurman, T Blokzijl, E A M Festen, B T Pham, K N Faber, E Brouwer, G Dijkstra   +6 more
doaj   +1 more source

TNF-α is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinomaResearch in context

EBioMedicine, 2019
Background: The role of tumor necrosis factor alpha (TNF-α) in targeted therapy for hepatocellular carcinoma (HCC) remains largely unknown. The current study aimed to clarify the mechanistic effects of targeting TNF-α to overcome sorafenib resistance in ...
Wenliang Tan, Xuan Luo, Wenda Li, Jinyi Zhong, Jun Cao, Sicong Zhu, Xianqing Chen, Rui Zhou, Changzhen Shang, Yajin Chen   +9 more
doaj   +1 more source

The effect of duration of wound skin tissue on MDA, TNF-α, IL-6, Caspase 3, VEGF levels, and granulation tissue thickness in the white rat (Rattus novergicus)

Bali Medical Journal, 2020
Introduction: Wound is the result of physical trauma that severs skin continuities. The damage typically causes an inflammatory reaction marked by increase ROS and tissue inflammation. However, this process is still needed to be further investigated. Therefore, this study aimed to evaluate plasma MDA, IL-6, TNF-α, Caspase-3 and VEGF levels, and the ...
Amru Sungkar, Danar Widyatmoko, Kristanto Yuli Yarso, Brian Wasita   +3 more
openaire   +1 more source

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett, Syeda Amrah Hashmi, Amaan Qureshi, Heather Spader, Shayan Moosa, Ifrah Zawar   +5 more
wiley   +1 more source

Photomicrographs of prostate sections immunostained with anti-caspase 3, anti-TNF-α, and anti-PCNA antibodies (Magnification × 400).

, 2023
(a-c) the control group and (d-f) DIA group showing negative cytoplasmic caspase 3 and TNF-α reactions and minimal nuclear PCNA expression, respectively. (g-i) BPH group showing mild cytoplasmic caspase 3, strong TNF-α reactions, and intense nuclear PCNA
Dina S. Hussein (17364412), A. S. Sadek (17364397), Heba Abdelrazak Abdelfattah (17364406), Saeedah Musaed Almutairi (7869272), Mohamed M. A. Elshaer (17364409), Mai A. M. Almoatasem (17364418), Rabab Ahmed Rasheed (12536918), R. T. Khattab (17364400), Fatma Alzahraa A. Elkhamisy (17364403), Azza Saleh Embaby (17364415)   +9 more
core   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Ekstrak Metanol Daun Kelor Menurunkan Kadar TNF-α dan IL-6 Serum, serta MDA Kolon Tikus yang Diinduksi DMBA

Jurnal Kedokteran Brawijaya, 2016
Ekstrak daun kelor (Moringa oleifera) dapat berfungsi sebagai anti oksidan, anti radang, dan anti kanker.TNF-α dan IL-6 merupakan sitokin proinflamasi yang berperan penting pada patogenesis kanker, sedangkan pada jaringan kanker sering ditemukan peningkatan kadar MDA.
Tinny Endang H, Dian Sukma H
openaire   +1 more source