Results 151 to 160 of about 3,516,666 (358)

Estudo de polimorfismos genéticos do HLA (classes I e II) e do TNF-α em doentes com sarcoidose

Revista Portuguesa de Pneumologia, 2008
Resumo: Introdução: A susceptibilidade genética na ocorrência da sarcoidose é sugerida por alguns factores, nomeadamente pela observação de casos de agregação familiar e a associação da raça a diferentes tipos de incidência e gravidade da doença.
António Morais, Helena Alves, Bruno Lima, Luís Delgado, Ricardo Gonçalves, Sandra Tafulo   +5 more
openaire   +2 more sources

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

Arthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J. T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source

TNF-α KO mice do not show microglial deramification or tinnitus after noise exposure.

, 2019
A. Example images of microglia stained with IBA1 antibody in TNF-α KO mice with (Noise_5d, 5 days after noise exposure) or without noise exposure (Control). Inserts show enlarged images of microglial morphology. B.
Hao Luo (454719), Genevieve Patterson (6852536), Sungchil Yang (613899), Tatiana A. Yatskievych (2620807), Emily Jean Leptich (6852539), Savannah L. Shoemaker (6852542), Alexander K. Zinsmaier (6852533), Li. S. Zhang (6852530), Edward Pace (457986), Weihua Wang (196992), Robert Gibboni (6852545), Shaowen Bao (260952), Jinsheng Zhang (457987)   +12 more
core   +1 more source

Microarray analysis in the presence/absence of anti-TNF-α Ab.

, 2023
IFN-α/β/γR knockout (KO) mice (8–10 weeks old) were infected intraperitoneally with 2 × 106 focus-forming units (FFU) of DENV-3 P12/08. Mice were injected with an anti-TNF-α Ab (n = 3) or control normal IgG (n = 4) on Days 1 and 2 p.i., and survival was ...
Mohamad Al Kadi (11987393), Masayuki Shimojima (241787), Shuetsu Fukushi (542663), Yasusi Ami (17357710), Tadaki Suzuki (251922), Tomoki Yoshikawa (367816), Hideki Ebihara (18294), Masayuki Saijo (324701), Supranee Phanthanawiboon (2159206), Yusuke Sakai (437974), Noriyo Nagata (389752), Daisuke Kamimura (435268), Masaaki Murakami (2677831), Takeshi Kurosu (538717), Daisuke Okuzaki (482418)   +14 more
core   +1 more source

TNF-α -308 A allele is associated with an increased risk of distant metastasis in rectal cancer patients from Southwestern China.

PLoS ONE, 2017
Tumor necrosis factor-α (TNF-α), an important factor in systematic inflammation, is reportedly involved in several cancer types. The TNF-α -308 G>A (rs1800629) polymorphism in the promoter region influences TNF-α production. The association between TNF-α
Zhen Li, Shu-An Li, Ya Sun, Yu Liu, Wen-Liang Li, Li Yang, Yong Duan, Jingyu Li, Hao Guo, Tian-Ning Zou, Yunlong Li, Kun-Hua Wang   +11 more
doaj   +1 more source

Insulin attenuates TNFα-induced hemopexin mRNA: An anti-inflammatory action of insulin in rat H4IIE hepatoma cells

Biochemistry and Biophysics Reports, 2017
Proinflammatory cytokines, including TNF-α and IL-6, can contribute to insulin resistance. Conversely, insulin has some actions that can be considered anti-inflammatory.
J. Lee Franklin, William L. Bennett, Joseph L. Messina   +2 more
doaj   +1 more source

MicroRNA-145 attenuates TNF-α-driven cartilage matrix degradation in osteoarthritis via direct suppression of MKK4

Cell Death and Disease, 2017
Cartilage dyshomeostasis contributes to osteoarthritis (OA) pathogenesis, and tumor necrosis factor (TNF)-α has critical role in this process by driving inflammatory cascades and cartilage degradation.
G. Hu, Xiao-Ying Zhao, Chuan-Dong Wang, Yi-Yun Geng, Jing-Yu Zhao, Jiajia Xu, Bin Zuo, Chen Zhao, Cheng-Long Wang, Xiao-Ling Zhang   +9 more
semanticscholar   +1 more source

Ekstrak Metanol Daun Kelor Menurunkan Kadar TNF-α dan IL-6 Serum, serta MDA Kolon Tikus yang Diinduksi DMBA

Jurnal Kedokteran Brawijaya, 2016
Ekstrak daun kelor (Moringa oleifera) dapat berfungsi sebagai anti oksidan, anti radang, dan anti kanker.TNF-α dan IL-6 merupakan sitokin proinflamasi yang berperan penting pada patogenesis kanker, sedangkan pada jaringan kanker sering ditemukan peningkatan kadar MDA.
Tinny Endang H, Dian Sukma H
openaire   +1 more source

High Dose (5mg) Daily Folic Acid Supplement in Healthy Brazilian Volunteers Increases Mononuclear TNF-α Expression and Reduces NK Cell Number and Activity

Blood, 2015
Abstract Background In Brazil, wheat and corn flour is fortified with 150 µg of folic acid (FA), the synthetic form of folate. Individuals with increased cell duplication, including pregnant women and patients with hemolytic anemia need increased amounts of folate.
Juliano Bertinato, Clovis Paniz, Maylla Rodrigues Lucena, Patrícia Mendonça da Silva Amorim, Guilherme Wataru Gomes, Maria Stella Figueiredo, Ralph Green, Elvira Maria Guerra Shinohara   +7 more
openaire   +1 more source

The effect of duration of wound skin tissue on MDA, TNF-α, IL-6, Caspase 3, VEGF levels, and granulation tissue thickness in the white rat (Rattus novergicus)

Bali Medical Journal, 2020
Introduction: Wound is the result of physical trauma that severs skin continuities. The damage typically causes an inflammatory reaction marked by increase ROS and tissue inflammation. However, this process is still needed to be further investigated. Therefore, this study aimed to evaluate plasma MDA, IL-6, TNF-α, Caspase-3 and VEGF levels, and the ...
Amru Sungkar, Danar Widyatmoko, Kristanto Yuli Yarso, Brian Wasita   +3 more
openaire   +1 more source