Results 161 to 170 of about 46,256 (200)
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Anti-trinitrophenyl (TNP) antibody detection by neutralization of TNP-coliphage T4
Immunochemistry, 1969Abstract Anti-trinitrophenyl antibodies are detected by the specific neutralization of bacteriophage T4 haptenated with the picryl radical (TNP). TNP-phage neutralization by anti-TNP is compared to neutralization by anti-phage. Anti-TNP neutralized haptenated phage by two separable first order processes.
P, Barber, M B, Rittenberg
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A Comparative Insight on the Newly Emerging Rifamycins: Rifametane, Rifalazil, TNP-2092 and TNP-2198
Current Medicinal Chemistry, 2022Abstract:Rifamycins are considered a milestone for tuberculosis (TB) treatment because of their proficient sterilizing ability. Currently, available TB treatments are complicated and need a long duration, which ultimately leads to failure of patient compliance.
Adila Nazli +4 more
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TNP-LPS induces an IgG anti-TNP immune response in mice
Cellular Immunology, 1979Abstract The trinitrophenylated derivatives of lipopolysaccharide (TNP-LPS) elicit a specific anti-TNP, thymus-independent immune response in mice. After a single injection of antigen, anti-TNP antibodies of IgM and IgG isotypes are detected at the cellular and at the humoral levels, in athymic nude mice as well as in conventional (C57B1/6 × DBA/2)F ...
Humbert, J, Motta, I, Truffa, bachi P
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Journal of Immunological Methods, 1976
Peroxidase (PO), alkaline phosphatase, and glucose oxidase, as well as Fab anti-PO, were coupled with varying molar ratios of trinitrophenyl (TNP) hapten. These reagents were evaluated for their ability to detect anti-TNP antibodies in the lymph node cells of Balb/c mice immunized with heavily-substituted TNP45 alkaline phosphate, which gave rise only ...
D E, Stage, S, Avrameas
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Peroxidase (PO), alkaline phosphatase, and glucose oxidase, as well as Fab anti-PO, were coupled with varying molar ratios of trinitrophenyl (TNP) hapten. These reagents were evaluated for their ability to detect anti-TNP antibodies in the lymph node cells of Balb/c mice immunized with heavily-substituted TNP45 alkaline phosphate, which gave rise only ...
D E, Stage, S, Avrameas
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TNP-470 inhibits intraabdominal adhesion formation
Journal of Pediatric Surgery, 2000Angiogenesis plays an integral role in wound healing and tissue remodeling. The authors hypothesized that inhibition of angiogenesis would reduce intraabdominal adhesion formation.In 98 C57BL6/J mice, a 2-cm midline laparotomy was performed and a 5 mm2 SILASTIC (Dow Corning, Midland, MI) patch fixed to the right side of the peritoneum.
S C, Chiang +4 more
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2,4,6‐Trinitrophenyl (TNP) responsiveness of anti‐TNP (Sp6) transgenic mice
European Journal of Immunology, 1991AbstractTransgenic mouse models have demonstrated clonal deletion as well as clonal anergy of monospecific, high‐avidity autoreactive B cell. The function and fate of naturally activated B cells, many of them displaying degenerate specificity including autoreactivity, are still a matter of debate. The question was pursued in Sp6‐transgenic mice. Sp6, a
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TNP-enzyme conjugates for the detection of anti-TNP antibody producing cells in vivo
Journal of Immunological Methods, 1984After injection of TNP-KLH in mice and TNP-BGG-PEN in rabbits, anti-TNP antibody-forming cells were observed in the spleen. When cryostat sections of the stimulated spleen were incubated with TNP-HRP conjugate, and then treated for HRP cytochemistry, the cytoplasm of anti-TNP-forming cells was stained red.
E, Claassen, N, Van Rooijen
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The Journal of Immunology, 1975
Abstract The trinitrophenyl hapten (TNP) has been covalently conjugated to bacterial lipopolysaccharides (LPS) to give TNP-LPS. The site of attachment has been suggested to be in the core polysaccharide and lipid A region of the molecule and approximately 2.4 hapten molecules are bound per monomer LPS molecule.
Jacobs, D M, Morrison, D C
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Abstract The trinitrophenyl hapten (TNP) has been covalently conjugated to bacterial lipopolysaccharides (LPS) to give TNP-LPS. The site of attachment has been suggested to be in the core polysaccharide and lipid A region of the molecule and approximately 2.4 hapten molecules are bound per monomer LPS molecule.
Jacobs, D M, Morrison, D C
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The Journal of Immunology, 1985
Abstract A most effective method for the induction of hapten-specific allergic contact sensitivity (CS) is via epicutaneous application of the hapten. Another effective method is by the administration of haptenated epidermal cells (EC) subcutaneously. The latter method induces more intense and longer lasting CS than does the subcutaneous
S, Shimada, S I, Katz
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Abstract A most effective method for the induction of hapten-specific allergic contact sensitivity (CS) is via epicutaneous application of the hapten. Another effective method is by the administration of haptenated epidermal cells (EC) subcutaneously. The latter method induces more intense and longer lasting CS than does the subcutaneous
S, Shimada, S I, Katz
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