Results 191 to 200 of about 53,707 (250)

Anti-trinitrophenyl (TNP) antibody detection by neutralization of TNP-coliphage T4

Immunochemistry, 1969
Abstract Anti-trinitrophenyl antibodies are detected by the specific neutralization of bacteriophage T4 haptenated with the picryl radical (TNP). TNP-phage neutralization by anti-TNP is compared to neutralization by anti-phage. Anti-TNP neutralized haptenated phage by two separable first order processes.
P, Barber, M B, Rittenberg
openaire   +3 more sources

A Comparative Insight on the Newly Emerging Rifamycins: Rifametane, Rifalazil, TNP-2092 and TNP-2198

Current Medicinal Chemistry, 2022
Abstract:Rifamycins are considered a milestone for tuberculosis (TB) treatment because of their proficient sterilizing ability. Currently, available TB treatments are complicated and need a long duration, which ultimately leads to failure of patient compliance.
Adila Nazli, David L. He, Huacheng Xu, Zhi-Peng Wang, Yun He   +4 more
openaire   +2 more sources

Two 2D multiresponsive luminescence coordination polymers for selective sensing of Fe3+, CrVI anions and TNP in aqueous medium

CrysteEngComm, 2019
Zn(ii)/Cd(ii)-based 2D coordination polymers have been synthesized as luminescence sensors for the selective and reversible sensing of Fe3+, CrO42−, Cr2O72− and TNP in water.
Ai-Mei Zhou, Han Wei, Wei Gao, Jie‐Ping Liu, Xiumei Zhang   +4 more
semanticscholar   +1 more source

Pyrazinyl-functionalized Zr(iv)-MOF for ultrasensitive detection of tyrosine/TNP and efficient CO2/N2 separation

Journal of Materials Chemistry C, 2019
A pyrazinyl-functionalized Zr(iv)-MOF shows ultrasensitive fluorescence sensing of Tyr/TNP and efficient CO2/N2 separation.
Jin-Min Liu, Jin-Xin Hou, Jie Liu, Xu Jing, Li-jun Li, Jian-Long Du   +5 more
semanticscholar   +1 more source

TNP-LPS induces an IgG anti-TNP immune response in mice

Cellular Immunology, 1979
Abstract The trinitrophenylated derivatives of lipopolysaccharide (TNP-LPS) elicit a specific anti-TNP, thymus-independent immune response in mice. After a single injection of antigen, anti-TNP antibodies of IgM and IgG isotypes are detected at the cellular and at the humoral levels, in athymic nude mice as well as in conventional (C57B1/6 × DBA/2)F ...
Humbert, J, Motta, I, Truffa, bachi P
openaire   +2 more sources

Detection of anti-TNP antibody-forming cells (AFC) with TNP-enzyme and TNP-Fab anti-enzyme conjugates

Journal of Immunological Methods, 1976
Peroxidase (PO), alkaline phosphatase, and glucose oxidase, as well as Fab anti-PO, were coupled with varying molar ratios of trinitrophenyl (TNP) hapten. These reagents were evaluated for their ability to detect anti-TNP antibodies in the lymph node cells of Balb/c mice immunized with heavily-substituted TNP45 alkaline phosphate, which gave rise only ...
D E, Stage, S, Avrameas
openaire   +2 more sources

Evaluation of a Dual-Acting Antibacterial Agent, TNP-2092, on Gut Microbiota and Potential Application in the Treatment of Gastrointestinal and Liver Disorders.

ACS Infectious Diseases, 2019
TNP-2092 is a unique multi-targeting drug conjugate with extremely low propensity for development of resistance. The in vitro activity of TNP-2092 against a panel of urease-producing bacteria was similar to that of rifaximin, a locally acting antibiotic ...
Ying Yuan, Xiaomei Wang, Xiangyi Xu, Yu Liu, Cancan Li, Meng Yang, Yiqing Yang, Zhenkun Ma   +7 more
semanticscholar   +1 more source

TNP-470 inhibits intraabdominal adhesion formation

Journal of Pediatric Surgery, 2000
Angiogenesis plays an integral role in wound healing and tissue remodeling. The authors hypothesized that inhibition of angiogenesis would reduce intraabdominal adhesion formation.In 98 C57BL6/J mice, a 2-cm midline laparotomy was performed and a 5 mm2 SILASTIC (Dow Corning, Midland, MI) patch fixed to the right side of the peritoneum.
S C, Chiang, C H, Cheng, K S, Moulton, J M, Kasznica, S L, Moulton   +4 more
openaire   +2 more sources

2,4,6‐Trinitrophenyl (TNP) responsiveness of anti‐TNP (Sp6) transgenic mice

European Journal of Immunology, 1991
AbstractTransgenic mouse models have demonstrated clonal deletion as well as clonal anergy of monospecific, high‐avidity autoreactive B cell. The function and fate of naturally activated B cells, many of them displaying degenerate specificity including autoreactivity, are still a matter of debate. The question was pursued in Sp6‐transgenic mice. Sp6, a
openaire   +2 more sources

TNP-enzyme conjugates for the detection of anti-TNP antibody producing cells in vivo

Journal of Immunological Methods, 1984
After injection of TNP-KLH in mice and TNP-BGG-PEN in rabbits, anti-TNP antibody-forming cells were observed in the spleen. When cryostat sections of the stimulated spleen were incubated with TNP-HRP conjugate, and then treated for HRP cytochemistry, the cytoplasm of anti-TNP-forming cells was stained red.
E, Claassen, N, Van Rooijen
openaire   +2 more sources