Results 11 to 20 of about 1,312 (166)
Bufalin Inhibits Cytokine Storm by Regulating TLR4/TLR3 Signaling Pathway [PDF]
Immunity, Inflammation and DiseaseBackground Bufalin is one main component of the dried venom from Bufo gargarizans Cantor, which has anti‐tumor, cardiotonic, anti‐inflammatory and other physiological activities.
Xixi Liu +11 more
doaj +3 more sources
A New Indole Alkaloid from the Toad Venom of Bufo bufo gargarizans [PDF]
Molecules, 2016 A new indole alkaloid named bufobutarginine (1), along with three known bufotenines, namely, serotonin (2), bufotenidine (3), and bufotenine (4), were isolated from the water extract of toad venom.
Ying-Hui Dai +6 more
doaj +2 more sources
Identification of anti-tumor components from toad venom. [PDF]
Oncol Lett, 2017 Secretion of granular glands from the skin of amphibians is a fascinating resource of active substances, particularly for cancer therapy in clinical practice of Traditional Chinese Medicine. A variety of anti-tumor peptides have been isolated from different toads and frogs; however, no anti-tumor peptides are reported in toad venom of Bufo gargarizans.
Gao F +6 more
europepmc +4 more sources
Chemical Profile and Multicomponent Quantitative Analysis for the Quality Evaluation of Toad Venom from Different Origins [PDF]
Molecules, 2019 Toad venom (Chansu), a traditional Chinese medicine (TCM), has been widely used for treating various cancer. However, it is considerably difficult to evaluate the quality of Chansu due to its complex chemical compositions.
Yueting Cao +3 more
doaj +2 more sources
Isolation, Identification and Chemical Modification of Bufadienolides from Bufo melanostictus Schneider and Their Cytotoxic Activities against Prostate Cancer Cells [PDF]
MoleculesThe traditional Chinese medicine toad venom (Venenum bufonis) has been extensively used to treat various diseases, including cancers, in China and other Southeast Asian countries.
Qingmei Ye +4 more
doaj +2 more sources
3α-Hydroxybufadienolides in Bufo gallbladders: structural insights and biotransformation [PDF]
Natural Products and BioprospectingBufadienolides, naturally occurring steroids primarily found in toads, have garnered attention for their pharmacological properties and ecological significance.
Li-Jun Ruan +2 more
doaj +2 more sources
Cellular and molecular mechanisms of arenobufagin in cancer therapy: a systematic review [PDF]
Discover OncologyThe search for effective and safe therapeutic options is the goal of clinical treatment for cancer patients. In recent years, natural products have received increasing attention in order to develop new drugs with good antitumor effects and fewer side ...
Si-Jun Wang +5 more
doaj +2 more sources
Toxins, 2021 Animal venoms, widespread throughout the world, are complex mixtures, the composition of which depends on the venom-producing species. The objective of this study was to contribute to the development of animal venom-based medicines by investigating the ...
Soo-Hyun Sung +5 more
doaj +1 more source
Toxins, 2021 Snakes of the genera Pseudocerastes and Eristicophis (Viperidae: Viperinae) are known as the desert vipers due to their association with the arid environments of the Middle East.
Bianca op den Brouw +14 more
doaj +1 more source
Case Reports in Ophthalmological Medicine, 2020 The common toad produces venom (bufotoxin) that is produced in the parotid gland of the toad as well as in the skin. This toxic compound is a potent inhibitor of Na+/K+-ATPase activity. Physiological effects of bufotoxin are similar to those of digitalis
Renato Pejic +2 more
doaj +1 more source